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The purpose of this study was to assess surgical results of internal limiting
membrane (ILM) maculorrhexis in macular hole surgery. This study is a part of
continuing prospective clinical trial of our team of researchers. Thirteen eyes
of 13 patients with idiopathic macular hole underwent vitrectomy with the
removal of posterior cortical vitreous, peeling of the macular ILM, and
intraocular gas tamponade, followed by postoperative face-down positioning. The
excised specimens were evaluated with transmission electron microscopy. Complete
closure of the hole was observed in all 13 eyes (100% anatomic success rate).
Visual improvement of 2 or more lines on ETDRS visual acuity chart was achieved
in 11 (85%) of the 13 eyes. Six (54.5%) eyes attained visual acuity of 20/50 or
better. Electron microscopy showed ILM in the removed specimens. ILM
maculorrhexis is a promising new surgical approach to close idiopathic macular
holes but requires further investigation and long-term evaluation.