Korean J Intern Med.  1997 Jan;12(1):96-99.

A case of idiopathic thyrotropin (TSH) deficiency

• Ichida T
• Kajita Y

Abstract

The first case of idiopathic thyrotropin (TSH) deficiency in an old woman with thyroid functioning adenoma was reported. She got subtotal thyroidectomy before about four years of her admission to our hospital because of fatigability, puffy face and leg edema. At time, she had low TSH and free T4 levels despite replacement therapy with desiccated thyroid. No response of only serum TSH after administration of combined stimulant containing TRH and repeated TRH suggested the failure of TSH secretion. CT MRI did not show any abnormality. These results indicated that her hypothyroidism was due to acquired idiopathic TSH deficiency.

MeSH Terms

Adenoma/surgery
Adenoma/diagnosis
Adenoma/complications*
Aged
Diagnosis, Differential
Female
Follow-Up Studies
Human
Hypothyroidism/physiopathology
Hypothyroidism/etiology*
Hypothyroidism/diagnosis
Thyroid Function Tests
Thyroid Neoplasms/surgery
Thyroid Neoplasms/diagnosis
Thyroid Neoplasms/complications*
Thyrotropin/deficiency*