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Spontaneous Rupture of Uterine Vessels during 3rd Trimester of Pregnancy

Kim TY, Kim YH, Kim JW, Kim AM, Yang YM, Yoon HK, Park SY, Park SJ, Bang HY

A 37-year-old pregnant woman, para 3, was transferred to our hospital at 30 weeks of gestational age with severe acute abdomen. Ultrasonography of the abdomen confirmed that body fluid around...
Recurrent parvovirus B19 infection-associated pure red cell aplasia in a kidney transplant patient

Gang S, Park S, Min Si, Hong J, Chang YH, Ha J, Yang J

Posttransplant anemia is a common complication after kidney transplantation. Parvovirus B19 (PVB19) infection can induce pure red cell aplasia (PRCA) in immunosuppressed transplant patients. We herein report a case of...
Next-generation sequencing analysis of exosomal microRNAs: Fusobacterium nucleatum regulates the expression profiling of exosomal microRNAs in human colorectal cancer cells

Yu MR, Kim HJ, Kang JW, Kim YH, Park HR

Colon cancer is one of the most common malignant tumors, but there are still a few validated biomarkers of colon cancer. Exosome-mediated microRNAs (miRNAs) have been recognized as potential biomarkers...
Full-mouth rehabilitation in a Stevens-Johnson syndrome patient with severely worn dentition and abnormal root development

Park YH, Ryu R, Ahn SG, Kim KA, Seo JM

Stevens-Johnson syndrome (SJS) is a cytotoxic immune disorder that causes serious damage to the skin and mucous membranes. SJS is a rare disorder that is triggered by particular medications or...
Clinical Features of Eyes with Polypoidal Choroidal Vasculopathy and No Recurrence Over One Year

Park JH, Lee K, Park YH

Purpose: We here describe the clinical features of eyes with polypoidal choroidal vasculopathy (PCV) that exhibited good visual acuity (VA) over one year without additional treatment. Methods: Patients newly diagnosed with...
Intracranial Metaplastic Meningioma : Clinical and Radiological Characteristics of 11 Cases

Kim T, Kim JW, Ji SY, Kang H, Kim KM, Kim YH, Park CK, Choi SH, Park SH

Objective : Metaplastic meningioma is an extremely rare subtype of World Health Organization (WHO) grade I meningioma. It has distinctive histological subtypes according to its own mesenchymal components. Owing to...
What Is the Ideal Entry Point for Transforaminal Endoscopic Lumbar Discectomy?

Lee JU, Park KJ, Choi MK, Lee YH, Kim DH, Kim KH

Objective : The method of approach during transforaminal endoscopic lumbar discectomy (TELD) has been the subject of repeated study. However, the ideal entry point during TELD has not been studied...
Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway

Hwangbo H, Kim SY, Lee H, Park SH, Hong SH, Park C, Kim GY, Leem SH, Hyun JW, Cheong J, Choi YH

The thioredoxin (Trx) system plays critical roles in regulating intracellular redox levels and defending organisms against oxidative stress. Recent studies indicated that Trx reductase (TrxR) was overexpressed in various types...
Mediation effect of herpes zoster derived by statin use on cardiovascular disease risk

Kim SH, Yun SC, Khang YH, Kim MC, Kwon SU, Park GM, Cho YR, Lee KM, Kim MH

Background/Aims: Although statins are widely used to reduce the risk of cardiovascular disease (CVD) including stroke and myocardial infarction (MI), it is reported that statin use increases the incidence of...
Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies

Hong J, Park HK, Park S, Lee A, Lee YH, Shin DY, Koh Y, Choi JY, Yoon SS, Choi Y, Kim I

Background/Aims: A link between oral cavity infections and chemotherapy-induced oral mucositis (CIOM) in patients with hematological malignancies (HMs) undergoing intensive chemotherapy (IC) or hematopoietic stem cell transplantation (HSCT) has been...
Development of a novel reverse transcription PCR and its application to field sample testing for feline calicivirus prevalence in healthy stray cats in Korea

Kim SJ, Park YH, Park KT

Background: Feline calicivirus (FCV) is a major and highly infectious pathogen in cats worldwide. However, there have been limited studies about the status of FCV infections in Korea. Objectives: To investigate...
Efficacy of dual progesterone administration (intramuscular and vaginal) for luteal support in fresh day 3 or day 4 embryo transfer cycles

Nho EJ, Hong YH, Park JH, Kim SK, Lee JR, Jee BC, Kim SH

Objective The aim of this study was to compare in vitro fertilization outcomes between fresh day 3 or day 4 embryo transfer cycles with dual progesterone (P) administration (intramuscular and...
High fat diet accelerates and exacerbates microgliosis and neuronal damage/death in the somatosensory cortex after transient forebrain ischemia in gerbils

Seo WJ, Ahn JH, Lee TK, Kim B, Lee JC, Park JH, Yoo YH, Shin MC, Cho JH, Won MH, Park Y

Obesity has been known as an independent risk factor for stroke. Effects of high-fat diet (HFD)-induced obesity on neuronal damage in the somatosensory cortex of animal models of cerebral ischemia...
Blood Transfusion for Elderly Patients with Hip Fracture: a Nationwide Cohort Study

Jang SY, Cha YH, Yoo JI, Oh T, Kim JT, Park CH, Choy WS, Ha YC, Koo KH

Background: This nationwide study aimed to investigate the blood transfusion status of elderly hip fracture patients and to examine the effect of packed red blood cell transfusion on all-cause mortality. Methods:...
Beneficial Effect of Chloroquine and Amodiaquine on Type 1 Diabetic Tubulopathy by Attenuating Mitochondrial Nox4 and Endoplasmic Reticulum Stress

Kang JM, Lee HS, Kim J, Yang DH, Jeong HY, Lee YH, Kim DJ, Park SH, Sung M, Kim J, An HJ, Lee SH, Lee SY

Background: Oxidative stress induced by chronic hyperglycemia is recognized as a significant mechanistic contributor to the development of diabetic kidney disease (DKD). Nonphagocytic nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) is...
A Complex Cortical Malformation Caused by a Mutation in the Tubulin-Encoding TUBB3 Gene

Lee YH, Park NH

Tubulinopathy commonly refers to complex congenital and non-progressive brain malformations caused by mutations in the tubulin genes. Among tubulin-encoding genes, TUBB3 has rarely been reported as a cause of complex...
Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice

Lee D, Park YH, Lee JE, Kim HS, Min KY, Jo MG, Kim HS, Choi WS, Kim YM

Mast cells (MCs) are systemically distributed and secrete several allergic mediators such as histamine and leukotrienes to cause type I hypersensitivity. Dasatinib is a type of anti-cancer agent and it...
Assessment of Hand Motor Function in a Non-human Primate Model of Ischemic Stroke

Won J, Yi KS, Choi CH, Jeon CY, Seo J, Kim K, Yeo HG, Park J, Kim YG, Jin YB, Koo BS, Lim KS, Lee S, Kim KJ, Choi WS, Park SH, Kim YH, Huh JW, Lee SR, Cha SH, Lee Y

  • KMID: 2506534
  • Exp Neurobiol.
  • 2020 Aug;29(4):300-313.
  • doi: 10.5607/en20023
Ischemic stroke results from arterial occlusion and can cause irreversible brain injury. A non-human primate (NHP) model of ischemic stroke was previously developed to investigate its pathophysiology and for efficacy...
Suicidal Risk in Depressed Patients with the Treatment by Antipsychotics and Antidepressant Compared to Antidepressant Monotherapy: A Pilot Study Using Psychiatric Common Data Model

Ha JH, Lee E, Lee D, Cho YH, Lee H, Park B, Son SJ

Objectives This study examined the effects of reducing suicide attempts when taking antipsychotics in combination with antidepressants in depressive patients. Methods Using a common data model of electronic medical records at...
What is the Role of Coordinators in the Secondary Fracture Prevention Program?

Cha YH, Ha YC, Park KS, Yoo JI

Background: The purpose of this study is to search for reports on the clinical effectiveness of FLS being implemented worldwide through the systematic review, analyze the roles of coordinators in...

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