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Surgical Interventions and Clinical Outcomes of Patients with Trisomy 18: a Single Center Experience

Oh MY, Lee BS, Cha T, Jeong J, Jung E, Kim EAR, Kim KS, Lee BH, Yoo HW

Objective: The purpose of this study was to investigate the impact of surgical interventions on the survival rate of the trisomy 18 and to provide the clinical information of the...
Preliminary study for the development of a visiting oral health care intervention program for the elderly based on community healthcare

Jang JH, Cho JW, Kim YJ, Ki JY, Jo KS, Kim JR, Park JE, Kim DH

Objectives: We evaluated the level of oral health status and oral health behavior in the elderly prior to their participation in a visiting oral health care intervention program as part...
Prevalence of Gastrointestinal and Cardiovascular Risk in Patients with Degenerative Lumbar Spinal Disease

Yang JH, Lee BH, Eum KS, Suk KS, Park JO, Kim HS, Lee HM, Moon SH

Background: Limited information is available about the proportion of patients with degenerative lumbar spinal disease (DLSD) who have gastrointestinal (GI) and cardiovascular (CV) risk factors. Many DLSD patients are prescribed...
“Suicide CARE” (Standardized Suicide Prevention Program for Gatekeeper Intervention in Korea): An Update

Park SC, Na KS, Kwon SJ, Kim M, Kim HJ, Baik M, Seol J, An EJ, Lee SM, Lee EJ, Lim M, Cho SJ, Kim GH, Kim N, Jeon HJ, Paik JW, Oh KS, Lee HY

Objective In 2011, “Suicide CARE” (Standardized Suicide Prevention Program for Gatekeeper Intervention in Korea) was originally developed for the early detection of warning signs of suicide completion, since there is...
Intraoperative blood loss and surgical time according to the direction of maxillary movement

Kim HS, Son JH, Chung JH, Kim KS, Choi J, Yang JY

Background Excessive bleeding is one of the most severe complications of orthognathic surgery (OGS). This study investigated the associations of intraoperative blood loss and surgical time with the direction of...
The Impact of COVID-19 on the Conduct of Clinical Trials for Medical Products in Korea

Jeon J, Kim H, Yu KS

Background: The number of clinical trials conducted in Korea continues to increase and an increasing proportion focus on severe and rare incurable diseases. After the start of the severe acute...
Drug use evaluation of opioid analgesics in pain management among patients with hematopoietic stem cell transplantation

Oh HJ, Hong SY, Jeong YM, Choi KS, Lee E, Lee E, Kim YJ, Bang SM

Background Hematopoietic stem cell transplantation (HSCT) patients usually experience mucositis, musculoskeletal pain associated with high-dose chemotherapy, radiation, post-HSCT infection, or graft-versus-host disease. Pain management is important for the patients’ quality of...
Influence of three BALB/c substrain backgrounds on the skin tumor induction efficacy to DMBA and TPA cotreatment

Kang MJ, Gong JE, Kim JE, Choi HJ, Bae SJ, Seo MS, Kim KS, Jung YS, Cho JY, Lim Y, Hwang DY

Differences in responsiveness of BALB/c substrains have been investigated in various fields, including diabetes induction, corpus callosum deficiency, virus-induced demyelinating disease, aggressive behavior and osteonecrosis. However, induction efficacy of skin...
Impact of gender on chronic obstructive pulmonary disease outcomes: a propensity scorematched analysis of a prospective cohort study

Cho J, Lee CH, Kim DK, Hwang HG, Kim YI, Choi HS, Park JW, Yoo KH, Jung KS, Lee SD

Background/Aims: Despite increasing awareness of the burden of chronic obstructive pulmonary disease (COPD) in women, knowledge regarding gender differences in COPD outcomes is limited. Therefore, we aimed to evaluate whether...
Proton pump inhibitor use is associated with hip fracture development: a nationwide populationbased cohort study

Min YW, Lee YC, Kim K, Ryu S, Hong KS, Jeon H, Kim YS, Park JH, Son HJ, Rhee PL

Background/Aims: Effect of proton pump inhibitor (PPI) use on the risk of hip fracture is controversial. This study aimed to clarify the association between PPI use and hip fracture risk using a...
Comparative analysis of restraint stress-induced depressive-like phenotypes in C57BL/6N mice derived from three different sources

Hwang DJ, Kwon KC, Hwang DY, Seo MS, Kim KS, Jung YS, Cho JY

C57BL/6NKorl mice are a novel mouse stock recently developed by the National Institute of Food and Drug Safety Evaluation in Korea. Extensive research into the nature of C57BL/6NKorl mice is...
Role of potassium channels in female reproductive system

Kim JM, Song KS, Xu B, Wang T

Potassium channels are widely expressed in most types of cells in living organisms and regulate the functions of a variety of organs, including kidneys, neurons, cardiovascular organs, and pancreas among...
Efficacy of additional tunica vaginalis flap coverage for protecting against urethrocutaneous fistulas in tubularized incised plate urethroplasty: A prospective, randomized controlled trial

Han JH, Song SH, Lee JS, Park S, Kim SJ, Kim KS

Purpose: We compared the protective effect of additional tunica vaginalis flap coverage combined with a dartos flap against urethrocutaneous fistulas in tubularized incised plate (TIP) urethroplasty in a randomized controlled...
Early Hydroxychloroquine Administration for Rapid Severe Acute Respiratory Syndrome Coronavirus 2 Eradication

Hong KS, Jang JG, Hur J, Lee JH, Kim HN, Lee W, Ahn JH

There are no proven therapeutics for Coronavirus disease 2019 (COVID-19) pneumonia outbreak. We observed and analyzed the clinical efficacy of the most used hydroxychloroquine (HCQ) for 30 days. In this study,...
Assessment of Hand Motor Function in a Non-human Primate Model of Ischemic Stroke

Won J, Yi KS, Choi CH, Jeon CY, Seo J, Kim K, Yeo HG, Park J, Kim YG, Jin YB, Koo BS, Lim KS, Lee S, Kim KJ, Choi WS, Park SH, Kim YH, Huh JW, Lee SR, Cha SH, Lee Y

  • KMID: 2506534
  • Exp Neurobiol.
  • 2020 Aug;29(4):300-313.
  • doi: 10.5607/en20023
Ischemic stroke results from arterial occlusion and can cause irreversible brain injury. A non-human primate (NHP) model of ischemic stroke was previously developed to investigate its pathophysiology and for efficacy...
Small Bowel Perforation Associated With Gastrointestinal Graft-Versus-Host Disease and Cytomegalovirus Enteritis in a Patient With Leukemia: A Case Report With Literature Review

Song KS, Kim MJ, Lim HK, Hong YH, Park SS, Hong CW, Park SC, Sohn DK, Han KS, Oh JH

Gastrointestinal graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation. Concomitant cytomegalovirus (CMV) enteritis worsens the prognosis of this condition. We report a case of small bowel...
Association between body temperature measured at the emergency department with prognosis in septic shock patients

Choi JH, Park YS, Chung SP, Shin TG, Kim WY, Choi SH, Jo YH, Kang GH, Shin J, Lim TH, Han KS, Suh GJ, Korean Shock Society (KoSS) Investigators

  • KMID: 2506061
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):346-354.
Objective: Prior studies have explored the relationship between initial body temperature (BT) and mortality in patients with sepsis in the emergency department (ED). However, there has been no study on...
Updates of Nursing Practice Guideline for Oral Care

Cho YA, Lee SH, Kim KS, Im HM, Kim TH, Choi MY, Seo HJ, Park HS, Wang KH, Kim CH, Choi HK

Purpose: This study aimed to update the previously published nursing practice guideline for oral care. Methods:The guideline were updated according to the manuals developed by National Institute for Health and...
Adjuvanticity of Processed Aloe vera gel for Influenza Vaccination in Mice

Song EJ, Españo E, Nam JH, Kim J, Shim KS, Shin E, Park YI, Lee CK, Kim JK

The effectiveness of current influenza vaccines is considered suboptimal, and 1 way to improve the vaccines is using adjuvants. However, the current pool of adjuvants used in influenza vaccination is...
Response to Inhaled Nitric Oxide and Clinical Outcome in Very Low Birth Weight Infants with Early Pulmonary Hypertension

Cho JY, Lee BS, Oh MY, Cha T, Jeong J, Jung E, Kim AR, Kim KS

Purpose: To determine the efficacy of inhaled nitric oxide (iNO) in very low birth weight (VLBW) infants with early pulmonary hypertension (PH). Methods: We reviewed the medical records of 22 preterm...

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