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Elevated serum interleukin 15 (IL-15) in Behcet's disease

Park KS, Min SY, Cho ML, Yoon CH, Kim YJ, Park JS, Choi JJ, Kim WU, Min DJ, Hong YS, Min JK, Park SH, Cho CS, Kim HY

  • KMID: 1598559
  • J Korean Rheum Assoc.
  • 2002 Jun;9(2):117-123.
OBJECTIVE: To evaluate clinical significance of interleukin 15 (IL-15) in patients with Behcet's disease (BD). METHODS: Serum samples were obtained from 31 patients with BD and 29 healthy controls. BD patients...
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Corrigendum: Targeting Interleukin-17 and Th17 in Immune Inflammatory Diseases

Cho ML

This erratum is being published to correct of author name.
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Expression of Programmed Death Ligand-1 (PD-L1) on B Cells Regulates IL-17 Production of Activated CD4+ T Cells

Woo YJ, Cho ML, Min JK, Ju JH, Ju S, Park SH, Kim HY

No abstract available.
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Effects of Hydroxychloroquine on the Metabolism of Fas ligand of T cells

Min JK, Lee HJ, Lee WS, Park SH, Min SY, Cho ML, Cho CS, Kim HY

  • KMID: 2202458
  • J Korean Rheum Assoc.
  • 2000 Jun;7(2):127-139.
OBJECTIVE: Hydroxychloroquine (HCQ) is a drug that has been used to treat autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. However, the specific mechanism for its pharmacologic...
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Inhibition of Vascular Endothelial Growth Factor Expression in Cultured Rheumatoid Synoviocytes by Nonsteroidal Anti-inflammatory Drugs

Kim YJ, Park JS, Choi JJ, Cho ML, Min SY, Kim WU, Park SH, Cho CS, Kim HY

  • KMID: 1587210
  • J Korean Rheum Assoc.
  • 2001 Dec;8(4):253-261.
OBJECTIVE: Vascular endothelial growth factor (VEGF),a potent angiogenic, permeability-enhancing cytokine plays an important role in chronic inflammatory process of rheumatoid arthritis (RA).Nonsteroidal anti-inflammatory drugs (NSAIDs)are the most widely used drugs...
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Urinary Excretion of Rantes is Elevated in Lupus Nephritis

Yoon CH, Park KS, Choi JJ, Cho ML, Min SY, Kim WU, Min DJ, Min JK, Hong YS, Park SH, Cho CS, Kim HY

  • KMID: 1598555
  • J Korean Rheum Assoc.
  • 2002 Jun;9(2):97-105.
OBJECTIVE: Infiltrating T cells and monocytes have been implicated in the pathogenesis of lupus nephritis (LN). Chemokines may play a key role in the recruitment of these cells. We investigated...
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Measurement of Interleukin-33 (IL-33) and IL-33 Receptors (sST2 and ST2L) in Patients with Rheumatoid Arthritis

Hong YS, Moon SJ, Joo YB, Jeon CH, Cho ML, Ju JH, Oh HJ, Heo YJ, Park SH, Kim HY, Min JK

The interleukin-33 (IL-33)/ST2 pathway has emerged as an intercellular signaling system that participates in antigen-allergen response, autoimmunity and fibrosis. It has been suggested that IL-33/ST2 signaling has been involved in...
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Inhibition of RIPK3 Pathway Attenuates Intestinal Inflammation and Cell Death of Inflammatory Bowel Disease and Suppresses Necroptosis in Peripheral Mononuclear Cells of Ulcerative Colitis Patients

Lee SH, Kwon Jy, Moon J, Choi J, Jhun J, Jung K, Cho KH, Darlami O, Lee HH, Jung ES, Shin DY, Lee BI, Cho ML

Receptor-interacting serine/threonine-protein kinase (RIPK) 3 is a member of the TNF receptor-I signaling complex and mediates necroptosis, an inflammatory cell death. Ulcerative colitis (UC) is an excessive inflammatory disease caused...
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Hyperimmunoglobulin E-recurrent infection syndrome in a patient with juvenile dermatomyositis

Min JK, Cho ML, Kim SC, Lee YS, Lee SH, Park SH, Hong YS, Cho CS, Kim HY

  • KMID: 759092
  • Korean J Intern Med.
  • 1999 Jan;14(1):95-98.
A 13-year-old girl presented with multiple skin abscesses. She was diagnosed as having juvenile dermatomyositis (DM) at the age of 7 years. She had suffered from recurrent skin...
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Mitochondrial Transplantation Ameliorates the Development and Progression of Osteoarthritis

Lee AR, Woo JS, Lee SY, Na HS, Cho KH, Lee YS, Lee JS, Kim SA, Park SH, Kim SJ, Cho ML

Osteoarthritis (OA) is a common degenerative joint disease characterized by breakdown of joint cartilage. Mitochondrial dysfunction of the chondrocyte is a risk factor for OA progression. We examined the therapeutic...
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Clinical significance of Th17 cells in kidney transplantation

Chung BH, Yang CW, Cho ML

Transplantation research has focused on cytotoxic T-cell and plasma cell/B-cell-targeted strategies, but little attention has been paid to the role of T helper 17 (Th17) cells in allograft dysfunction. However,...
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IL-4 Induces CD4+CD25+ Regulatory T Cells from CD4+CD25- T Cells in Peripheral Blood

Heo SB, Cho ML, Park MK, Min SY, Joo JH, Park KS, Cho YK, Yoon CH, Park SH, Kim HY

  • KMID: 2334824
  • J Korean Rheum Assoc.
  • 2005 Dec;12(4):263-277.
OBJECTIVE: The CD4+CD25+ regulatory T cells (Treg) can be induced by TGFbeta and IL-10 in the periphery, and understanding the biological function of cytokine-induced Treg is critically important for the...
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Reciprocal Activation of Fibroblast-like Synoviocyte and Type II Collagen-reactive T cell in Rheumatoid Arthritis

Yoon CH, Park MK, Cho ML, Ko HJ, Park KS, Kim WU, Min JK, Lee SH, Hong YS, Park SH, Cho CS, Kim HY

  • KMID: 2202351
  • J Korean Rheum Assoc.
  • 2004 Mar;11(1):25-36.
OBJECTIVE: To investigate the interaction between type II collagen (CII)-reactive T cell and fibroblast-like synoviocyte in rheumatoid arthritis (RA). METHODS: Peripheral blood T cells from RA patients were cultured with...
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Immunological pathogenesis of inflammatory bowel disease

Lee SH, Kwon JE, Cho ML

Inflammatory bowel disease (IBD) is a chronic inflammatory state of the gastrointestinal tract and can be classified into 2 main clinical phenomena: Crohn's disease (CD) and ulcerative colitis (UC). The...
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Why Should We Consider Potential Roles of Oral Bacteria in the Pathogenesis of Sjögren Syndrome?

Chang SH, Park SH, Cho ML, Choi Y

Sjögren syndrome (SS) is a chronic autoimmune disorder that primarily targets the salivary and lacrimal glands. The pathology of these exocrine glands is characterized by periductal focal lymphocytic infiltrates, and...
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T cell Proliferative Response to Type II collagen is related to Inflammatory Process and Joint Damage in Rheumatoid Arthritis

Choi JJ, Kim WU, Cho ML, Lee MS, Seo YI, Min DJ, Park SH, Cho CS, Kim HY

  • KMID: 1598558
  • J Korean Rheum Assoc.
  • 2002 Jun;9(2):106-116.
OBJECTIVE: To investigate the role of T cell responses to type II collagen (CII) in disease progression in rheumatoid arthritis (RA). METHODS: T cell proliferative responses to bovine CII by peripheral...
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1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis

Kim H, Baek S, Hong SM, Lee J, Jung SM, Lee J, Cho ML, Kwok SK, Park SH

BACKGROUND: Immune cells express the vitamin (vit) D receptor, and vit D is a potent immune-modulator. A negative correlation between serum vit D levels and rheumatoid arthritis (RA) disease activity...
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Vitamin D Attenuates Pain and Cartilage Destruction in OA Animals via Enhancing Autophagic Flux and Attenuating Inflammatory Cell Death

Jhun J, Woo JS, Kwon JY, Na HS, Cho KH, Kim SA, Kim SJ, Moon SJ, Park SH, Cho ML

Osteoarthritis (OA) is the most common form of arthritis associated with ageing. Vitamin D has diverse biological effect on bone and cartilage, and observational studies have suggested it potential benefit...
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Generation and maintenance of type II collagen-specific T-cell line expressing conserved TCR-CDR3 motifs among patients with rheumatoid arthritis Author

Kim SH, Cho ML, Youn JH, Park SH, Hwang SY, Kim HY, Cho CS

BACKGROUND: To determine the molecular structure of type II collagen-specific T-cell receptors associated with rheumatoid arthritis (RA). METHODS: We generated CII-specific T-cell lines of 8 RA patient s by prolonged in...
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Immune Regulatory Function of Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase in Orally Tolerance to Type II Collagen-induced Animal Model

Park MJ, Min SY, Park KS, Cho ML, Cho YG, Min JK, Yoon CH, Park SH, Kim HY

BACKGROUND: Immune regulatory dendritic cells (DCs) play an important role in maintaining self-tolerance. Recent evidences demonstrate that DCs expressing indoleamine 2,3-dioxygenase (IDO), which is involved in tryptophan catabolism, play an...
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