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Spurious Thyroid Function Test Results due to Biotin Interference: a Report of Three Cases and a Literature Review

Park JY, Choi W, Yoon JH, Kang HC

Biotin (vitamin B7) is a water-soluble vitamin used as a co-enzyme for carboxylases essential for human metabolism. The high affinity to streptavidin makes biotin an important substance in immunoassays. Excessive...
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Additional Value of Integrated 18 F-FDG PET/MRI for Evaluating Biliary Tract Cancer: Comparison with Contrast-Enhanced CT

Yoo J, Lee JM, Yoon JH, Joo I, Lee DH

Objective: To evaluate the value of 18 F-fluorodeoxyglucose PET/MRI added to contrast-enhanced CT (CECT) in initial staging, assessment of resectability, and postoperative follow-up of biliary tract cancer. Materials and Methods: This...
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A Patient With Late-onset Limb-girdle Muscular Dystrophy Type 2B Mimicking Dermatomyositis: A Case Report and Review

Kim MJ, Oh YJ, Hong YH, Park SH, Oh JS, Kim MJ, Chae JH, Shin K

Limb-Girdle Muscular Dystrophy 2B (LGMD2B) presents with proximal and/or distal muscle weakness and markedly high creatine kinase level. It is caused by the loss of dysferlin due to mutations in...
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Combined Effects of Depression and Chronic Disease on the Risk of Mortality: The Korean Longitudinal Study of Aging (2006-2016)

Kim H, Kim SH, Cho YJ

Background: The prevalence of depression is much higher in people with chronic disease than in the general population. Depression exacerbates existing physical conditions, resulting in a higher-than-expected death rate from...
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Differences in mandibular condyle and glenoid fossa morphology in relation to vertical and sagittal skeletal patterns: A cone-beam computed tomography study

Noh KJ, Baik HS, Han SS, Jang W, Choi YJ

Objective: This study aimed to evaluate the following null hypothesis: there are no differences in the morphology of the temporomandibular joint (TMJ) structures in relation to vertical and sagittal cephalometric...
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Role of Contrast-Enhanced Ultrasound as a Second-Line Diagnostic Modality in Noninvasive Diagnostic Algorithms for Hepatocellular Carcinoma

Kang HJ, Lee JM, Yoon JH, Han JK

Objective: To investigate the diagnostic performance of contrast-enhanced ultrasound (CEUS) and its role as a second-line imaging modality after gadoxetate-enhanced MRI (Gd-EOB-MRI) in the diagnosis of hepatocellular carcinoma (HCC) among...
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Burnout as a Mediator in the Relationship between Work-Life Balance and Empathy in Healthcare Professionals

Seo HY, Lee DW, Nam S, Cho Sj, Yoon JY, Hong YC, Lee N

Objective This cross-sectional study aimed to 1) explore the relationships among work-life balance (WLB), burnout, and empathy and 2) investigate the roles of the subtypes of burnout relating to WLB...
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Prognostic Value of Tumor Regression Grade on MR in Rectal Cancer: A Large-Scale, Single-Center Experience

Yoen H, Park HE, Kim SH, Yoon JH, Hur BY, Bae JS, Kim JH, Oh HJ, Han JK

Objective: To determine the prognostic value of MRI-based tumor regression grading (mrTRG) in rectal cancer compared withpathological tumor regression grading (pTRG), and to assess the effect of diffusion-weighted imaging (DWI)...
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The clinical meaning of pre- and post-ablation thyroglobulin levels at first radioiodine therapy in patients with papillary thyroid cancer

Kim HK, Yoon JH, Cho JS, Kwon SY, Yoo SW, Kang HC

Background/Aims: This study was conducted to identify prognostic factors in patients with papillary thyroid cancer (PTC) at the time of first radioactive iodine (RAI) therapy, and to evaluate the clinical...
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Effects of Functions of Daily Living, Depression, and Anxiety on Catastrophizing Pain among Patients Undergoing Lumbar Spinal Surgery

Yoon JE, Cho OH

Purpose: The aim of this study was to investigate the influence of daily life functions, anxiety, and depression on pain catastrophizing among patients undergoing lumbar spinal surgery. Methods: This study...
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Deep Learning Algorithm for Automated Segmentationand Volume Measurement of the Liver and Spleen UsingPortal Venous Phase Computed Tomography Images

Ahn Y, Yoon JS, Lee SS, Suk HI, Son JH, Sung YS, Lee Y, Kang BK, Kim HS

Objective: Measurement of the liver and spleen volumes has clinical implications. Although computed tomography (CT)volumetry is considered to be the most reliable noninvasive method for liver and spleen volume measurement,...
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Effects of soft tissue grafting prior to orthodontic treatment on preventing gingival recession in dogs

Song YW, Jung H, Han SY, Paeng KW, Kim MJ, Cha JK, Choi YJ, Jung UW

Purpose: This study was conducted to assess the efficacy of prophylactic gingival grafting in the mandibular anterior labial area for preventing orthodontically induced gingival recession. Methods: Eight mongrel dogs received gingival...
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Comparison of point and 2-dimensional shear wave elastography for the evaluation of liver fibrosis

Lee SM, Kim MJ, Yoon JH, Hong W, Ha HI, Lee K, Choe JY, Lee JW, Yoon SY, Han J

Purpose: This study aimed to assess the technical performance of ElastQ Imaging compared with ElastPQ and to investigate the correlation between liver stiffness (LS) values obtained using these two techniques. Methods:...
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ERK Regulates NeuroD1-mediated Neurite Outgrowth via Proteasomal Degradation

Lee Ty, Cho IS, Bashyal N, Naya FJ, Tsai MJ, Yoon JS, Choi JM, Park CH, Kim SS, Suh-Kim H

  • KMID: 2503980
  • Exp Neurobiol.
  • 2020 Jun;29(3):189-206.
  • doi: 10.5607/en20021
Neurogenic differentiation 1 (NeuroD1) is a class B basic helix-loop-helix (bHLH) transcription factor and regulates differentiation and survival of neuronal and endocrine cells by means of several protein kinases, including...
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Prognostic impact of hepatitis B or C on intrahepatic cholangiocarcinoma

Seo JW, Kwan BS, Cheon YK, Lee TY, Shim CS, Kwon SY, Choe WH, Yoo BC, Yoon JM, Lee JH

Background/Aims: Intrahepatic cholangiocarcinoma (ICC) is the second-most common primary liver malignancy, arising from the peripheral intrahepatic bile duct epithelium. Hepatitis B virus (HBV) or hepatitis C virus (HCV) may be...
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Identification of Free-Living Amoebas in Tap Water of Buildings with Storage Tanks in Korea

Lee DI, Park SH, Baek JH, Yoon JW, Jin SI, Han KE, Yu HS

Free-living amoebas (FLAs) can cause severe disease in humans and animals when they become infected. However, there are no accurate survey reports on the prevalence of FLAs in Korea. In...
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Macular Microvasculature in High Myopia without Pathologic Changes: An Optical Coherence Tomography Angiography Study

Min CH, Al-Qattan HM, Lee JY, Kim JG, Yoon YH, Kim YJ

Purpose To investigate macular microvasculature changes using optical coherence tomography angiography (OCTA) and analyze their correlation with the structural parameters in highly myopic eyes. Methods We measured the area of the foveal avascular...
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Reproducibility of ultrasound attenuation imaging for the noninvasive evaluation of hepatic steatosis

Yoo J, Lee JM, Joo I, Lee DH, Yoon JH, Kang HJ, Ahn SJ

Purpose: The purpose of this study was to evaluate the intra-observer reproducibility of ultrasound attenuation imaging (ATI) for the noninvasive assessment of hepatic steatosis in patients with suspected hepatic steatosis...
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Neurogenin-1 Overexpression Increases the Therapeutic Effects of Mesenchymal Stem Cells through Enhanced Engraftment in an Ischemic Rat Brain

Kim GH, Subash M, Yoon JS, Jo D, Han J, Hong JM, Kim SS, Kim HS

Background and Objectives: Stem cell therapy is a promising strategy for treating neurological diseases but its effectiveness is influenced by the route of administration and the characteristics of the stem...
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Mutation of ten-eleven translocation-2 is associated with increased risk of autoimmune disease in patients with myelodysplastic syndrome

Oh YJ, Shin DY, Hwang SM, Kim SM, Im K, Park HS, Kim JA, Song YW, Márquez A, Martín J, Lee DS, Park JK

Background/Aims: Myelodysplastic syndrome (MDS) is caused by genetic and epigenetic alteration of hematopoietic precursors and immune dysregulation. Approximately 20% of patients with MDS develop an autoimmune disease (AID). Here, we...
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