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Diagnostic Performance of Serum Asialo α1 -Acid Glycoprotein Levels to Predict Liver Cirrhosis

Lim DH, Kim M, Jun DW, Kwak MJ, Yoon JH, Lee KN, Lee HL, Lee OY, Yoon BC, Choi HS, Kang BK

Background/Aims: To date, studies on various noninvasive techniques have been suggested to evaluate the degree of liver fibrosis. We aimed to investigate the diagnostic performance of se-rum asialo α1-acid glycoprotein...
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Recurrent Coronary Artery Vasospasm in a Patient with Hepatocellular Carcinoma Treated with Sorafenib: a Case Report and Literature Review

Lim DH, Yoon JH, Jun DW, Lee OY, Yoon BC, Lee HR, Kim KS, Choi HS

Tyrosine kinase inhibitors are widely used as targeted treatments for various malignancies. Sorafenib is an orally active tyrosine kinase inhibitor that blocks the signaling pathways of several growth factors. Its...
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Effect of DA-9701, a Novel Prokinetic Agent, on Post-operative Ileus in Rats

Lee SP, Lee OY, Lee KN, Lee HL, Choi HS, Yoon BC, Jun DW

  • KMID: 2367462
  • J Neurogastroenterol Motil.
  • 2017 Jan;23(1):109-116.
  • doi: 10.5056/jnm16003
BACKGROUND/AIMS: Post-operative ileus (POI) is a common complication of abdominal surgery. DA-9701, an extract of Pharbitis Semen and Corydalis Tuber, is a new prokinetic agent that also alleviates visceral pain....
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MUC Expression in Gallbladder Epithelial Tissues in Cholesterol-Associated Gallbladder Disease

Yoo KS, Choi HS, Jun DW, Lee HL, Lee OY, Yoon BC, Lee KG, Paik SS, Kim YS, Lee J

BACKGROUND/AIMS: Gallstone pathogenesis is linked to mucin hypersecretion and bacterial infection. Several mucin genes have been identified in gallbladder epithelial cells (GBECs). We investigated MUC expression in cholesterol-associated gallbladder disease...
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The Effect of DA-6034 on Intestinal Permeability in an Indomethacin-Induced Small Intestinal Injury Model

Kwak DS, Lee OY, Lee KN, Jun DW, Lee HL, Yoon BC, Choi HS

BACKGROUND/AIMS: DA-6034 has anti-inflammatory activities and exhibits cytoprotective effects in acute gastric injury models. However, explanations for the protective effects of DA-6034 on intestinal permeability are limited. This study sought...
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A Rare Cause of Acute Upper Abdominal Pain: Diverticulitis of the 3rd Portion of the Duodenum

Ahn YW, Lee KN, Doo EY, Yoo KD, Kim YT, Lee KW, Lee OY, Yoon BC

Duodenal diverticulitis is a rare cause of upper abdominal pain and is usually not considered when evaluating patients with acute upper abdominal pain. Furthermore, the duodenum is located near the...
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Low-dose steroid-induced tumor lysis syndrome in a hepatocellular carcinoma patient

Kim JO, Jun DW, Tae HJ, Lee KN, Lee HL, Lee OY, Choi HS, Yoon BC, Hahm JS

Tumor lysis syndrome is rare in hepatocellular carcinoma (HCC), but it has been reported more frequently recently in response to treatments such as transcatheter arterial chemoembolization (TACE), radiofrequency thermal ablation...
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Prevalence of Gastric Subepithelial Tumors in Korea: A Single Center Experience

Lee JH, Lee HL, Ahn YW, Lee KN, Jun DW, Lee OY, Han DS, Yoon BC, Choi HS

BACKGROUND/AIMS: The incidental finding of gastrointestinal subepithelial tumors (SETs) is increasing with national cancer screening endoscopy. In a Swedish population, screening endoscopy found a prevalence of SETs of 0.36%. However,...
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Effects of DA-9701, a Novel Prokinetic Agent, on Phosphorylated Extracellular Signal-Regulated Kinase Expression in the Dorsal Root Ganglion and Spinal Cord Induced by Colorectal Distension in Rats

Lee SP, Lee KN, Lee OY, Lee HL, Jun DW, Yoon BC, Choi HS, Hwang SJ, Lee SE

  • KMID: 1774540
  • Gut Liver.
  • 2014 Mar;8(2):140-147.
BACKGROUND/AIMS: DA-9701, a standardized extract of Pharbitis Semen and Corydalis Tuber, is a new prokinetic agent that exhibits an analgesic effect on the abdomen. We investigated whether DA-9701 affects visceral...
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Visceral Fat as a Useful Parameter in the Differential Diagnosis of Crohn's Disease and Intestinal Tuberculosis

Ko JK, Lee HL, Kim JO, Song SY, Lee KN, Jun DW, Lee OY, Han DS, Yoon BC, Choi HS, Hahm JS, Kim SY

BACKGROUND/AIMS: Because of the similarities in the clinical presentations of Crohn's disease (CD) and intestinal tuberculosis (ITB), differential diagnosis is critical. Mesenteric adipose tissue hypertrophy and creeping fat are characteristic...
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Endoscopic Treatment of a Symptomatic Ileal Lipoma with Recurrent Ileocolic Intussusceptions by Using Cap-Assisted Colonoscopy

Lee ES, Lee KN, Choi KS, Lee HL, Jun DW, Lee OY, Yoon BC, Choi HS

  • KMID: 2425266
  • Clin Endosc.
  • 2013 Jul;46(4):414-417.
A 73-year-old woman presented with intermittent abdominal pain and weight loss of 15 kg for 2 years. Colonoscopy revealed an erythematous polypoid tumor with a long and wide stalk in...
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Association between Symptoms of Irritable Bowel Syndrome and Methane and Hydrogen on Lactulose Breath Test

Lee KN, Lee OY, Koh DH, Sohn W, Lee SP, Jun DW, Lee HL, Yoon BC, Choi HS, Hahm JS

Whether hydrogen and methane gas produced during lactulose breath test (LBT) are associated with symptoms of irritable bowel syndrome (IBS) is not determined. We aimed to investigate whether hydrogen and...
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Lipoic Acid Prevents the Changes of Intracellular Lipid Partitioning by Free Fatty Acid

Kim DC, Jun DW, Jang EC, Kim SH, Kim EK, Lee SP, Lee KN, Lee HL, Lee OY, Yoon BC, Choi HS

  • KMID: 2135074
  • Gut Liver.
  • 2013 Mar;7(2):221-227.
BACKGROUND/AIMS: It is suggested that the hepatic lipid composition is more important than lipid quantity in the pathogenesis of non-alcoholic steatohepatitis. We examined whether lipoic acid (LA) could alter intrahepatic...
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The Relationship Between Existence of Typical Symptoms and Psychological Factors in Patients With Erosive Esophagitis

Lee SP, Lee KN, Lee OY, Lee HL, Choi HS, Yoon BC, Jun DW, Sohn W, Cho SC

  • KMID: 2325925
  • J Neurogastroenterol Motil.
  • 2012 Jul;18(3):284-290.
BACKGROUND/AIMS: In Asian countries including Korea, the prevalence of gastroesophageal reflux disease (GERD) is on the rise and its clinical impact has been emphasized. The purpose of this study was...
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A Case of Natural Killer Like T Cell Lymphoma Misdiagnosed as Behcet's Enteritis of the Terminal Ileum

Joo YW, Koh DH, Lee KN, Lee HL, Jun DW, Yoon BC, Choi HS, Lee OY

Primary natural killer (NK) cell like T cell lymphoma of the terminal ileum is extremely rare. It most frequently occurs in the nasal or paranasal areas and less frequently in...
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Augmenting Effect of DA-9601 on Ghrelin in an Acute Gastric Injury Model

Baek YH, Lee KN, Jun DW, Yoon BC, Kim JM, Oh TY, Lee OY

  • KMID: 2167274
  • Gut Liver.
  • 2011 Mar;5(1):52-56.
BACKGROUND/AIMS: Acute gastric injury by alcohol or indomethacin has been reported to be prevented by DA-9601, an extract of the herb Artemisia asiatica. Ghrelin, an endogenously produced gastrointestinal peptide hormone,...
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Correlation between Complicated Diverticulitis and Visceral Fat

Jeong JH, Lee HL, Kim JO, Tae HJ, Jung SH, Lee KN, Jun DW, Lee OY, Yoon BC, Choi HS, Hahm JS, Song SY

The aim of this study was to examine the relationship of complications related to diverticulitis and visceral obesity. The study was based on a retrospective case note review conducted at...
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Differences in Clinical Characteristics between Patients with Non-Erosive Reflux Disease and Erosive Esophagitis in Korea

Ha NR, Lee HL, Lee OY, Yoon BC, Choi HS, Hahm JS, Ahn YH, Koh DH

Gastroesophageal reflux disease (GERD) is caused by abnormal reflux of gastric contents into the esophagus. GERD can be divided into two groups, erosive esophagitis and non-erosive reflux disease (NERD). The...
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The Effect of Forward and Backward Treadmill walking Training on Muscular Strength of Lower Extremities before and after Exhausting Exercise

Ryu HY, Yoon BC, Park SK, Park HC, Yoon SJ

  • KMID: 2288623
  • Korean J Sports Med.
  • 2010 Jun;28(1):37-43.
The purpose of this study was to investigate the physiological effects of forward and backward walking training on lower extremity muscle strength before and after exhausting exercise. Fourteen healthy male...
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The Differences in Prevalence and Sociodemographic Characteristics of Irritable Bowel Syndrome According to Rome II and Rome III

Park DW, Lee OY, Shim SG, Jun DW, Lee KN, Kim HY, Lee HL, Yoon BC, Choi HS

  • KMID: 2326141
  • J Neurogastroenterol Motil.
  • 2010 Apr;16(2):186-193.
BACKGROUND/AIMS: Irritable bowel syndrome (IBS) is one of the most frequently observed disorders by primary care and practitioners. The aim of this study was to estimate the prevalence of IBS...
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