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Effect of bosentan on the production of proinflammatory cytokines in a rat model of emphysema

Gamze K, Mehmet HM, Deveci F, Turgut T, ilhan F, Ozercan I

  • KMID: 1090964
  • Exp Mol Med.
  • 2007 Oct;39(5):614-620.
Endothelin (ET) receptor antagonists have been developed to produce a reduction of ET related effects in various diseases, as well as in animal models of airway inflammation. We aimed to...
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The effects of low dose leukotriene receptor antagonist therapy on airway remodeling and cysteinyl leukotriene expression in a mouse asthma model

Muz MH, Deveci F, Bulut Y, Ilhan N, Yekeler H, Turgut T

  • KMID: 1111403
  • Exp Mol Med.
  • 2006 Apr;38(2):109-118.
Airway structural changes that occur in patients with asthma in response to persistent inflammation are termed airway remodeling. The cysteinyl leukotrienes (LTC4, D4 and E4) are known to play important...
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