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Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers

Song JY, Cheong HJ, Kim SR, Lee SE, Kim SH, Noh JY, Yoon YK, Choi WS, Park DW, Sohn JW, Kim WJ, Kim MJ

Hospital-based surveillance for adverse events was conducted on healthcare workers after they received the first dose of coronavirus disease 2019 (COVID-19) vaccine. Among the two new platform vaccines (messenger RNA-...
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Impact of Grilling Meat or Fish at Home on Peak Expiratory Flow Rate in Adults With Asthma

Lee H, Chung SJ, Park JS, Kim S, Park DW, Sohn JW, Kim SH, Park CS, Yoon HJ

Grilling, a common cooking method worldwide, can produce more toxic gases than other cooking methods. However, the impact of frequently grilling meat or fish at home on airflow limitation in...
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Korean Registry for Improving Sepsis Survival (KISS): Protocol for a Multicenter Cohort of Adult Patients with Sepsis or Septic Shock

Kim JH, Ku NS, Kim YJ, Kim HB, Seok H, Lee DG, Lee JS, Jeong SJ, Choi JH, Sohn JW, Kim MJ, Park DW

Sepsis is one of the significant causes of morbidity and mortality. The burden caused by sepsis has continued to increase in recent years in the Korea, highlighting the urgent need...
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Trend of Olfactory and Gustatory Dysfunction in COVID-19 Patients in a Quarantine Facility

Seo MY, Seok H, Hwang SJ, Choi HK, Jeon JH, Sohn JW, Park DW, Lee SH, Choi WS

Background: Olfactory and gustatory dysfunction has been reported as characteristic symptoms of coronavirus disease 2019 (COVID-19). This study evaluated olfactory and gustatory dysfunction in mild COVID-19 patients using validated assessment...
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Significance of Decreasing Rate of HIV and HBV Co-infection in a Nationwide Korean HIV/AIDS Cohort

Kim Y, Kim SW, Kwon KT, Chang HH, Jun Y, Sohn JW, Park DW, Song JY, Choi JY, Kim HY, Kim JM, Choi BY, Choi Y, Kee MK, Yoo MS, Lee JG

From December 2006 to December 2016, 1093 human immunodeficiency virus (HIV) individuals < 70 years enrolled in Korea human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) cohort were analyzed to investigate...
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Characteristics of Klebsiella pneumoniae Isolates from Stool Samples of Patients with Liver Abscess Caused by Hypervirulent K. pneumoniae

Kim JH, Jeong Y, Lee CK, Kim SB, Yoon YK, Sohn JW, Kim MJ

BACKGROUND: Hypervirulent Klebsiella pneumoniae (hvKP) has been the most significant pathogen for liver abscesses in East Asia including the Republic of Korea (ROK). Although gastrointestinal colonization of K. pneumoniae may...
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A Computational Modeling Reveals That Strength of Inhibitory Input, E/I Balance, and Distance of Excitatory Input Modulate Thalamocortical Bursting Properties

Park S, Sohn JW, Cho J, Huh Y

The thalamus is a brain structure known to modulate sensory information before relaying to the cortex. The unique ability of a thalamocortical (TC) neuron to switch between the high frequency...
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Implantable Neural Probes for Brain-Machine Interfaces – Current Developments and Future Prospects

Choi JR, Kim SM, Ryu RH, Kim SP, Sohn JW

A Brain-Machine interface (BMI) allows for direct communication between the brain and machines. Neural probes for recording neural signals are among the essential components of a BMI system. In this...
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Safety and Efficacy of Ziagen (Abacavir Sulfate) in HIV-Infected Korean Patients

Ann H, Kim KH, Choi HY, Chang HH, Han SH, Kim KH, Lee JS, Kim YS, Park KH, Kim YK, Sohn JW, Yun NR, Lee CS, Choi YW, Lee YS, Kim SW

BACKGROUND: Abacavir is a widely-used nucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus (HIV) infection. Mandatory postmarketing surveillance was conducted in Korea to monitor the safety and...
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Infective Endocarditis Presenting as Endogenous Endophthalmitis Secondary to Streptococcus agalactiae in a Healthy Adult: Case Report and Literature Review

Sim YR, Lee YJ, Park SW, Kim SH, Choi JH, Choi JY, Kim MJ, Sohn JW, Ahn J, Yoon YK

Endogenous endophthalmitis secondary to group B Streptococcus (GBS) is extremely rare, particularly in healthy adults. However, the visual prognosis is poor. We report the first South Korean case of GBS...
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Genetic polymorphisms of interleukin-10 and transforming growth factor-β1 and antituberculosis drugs-induced liver injury

Jung S, Kim SH, Sohn JW, Yoon HJ, Shin DH, Jee YK, Kim SH

PURPOSE: Drug-induced liver injury is one of the serious adverse reactions resulting in severe morbidity and discontinuation of medications. Previously, IL-10 gene polymorphism has been reported to be associated with...
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Immunogenicity and Safety of a Live Attenuated Zoster Vaccine (ZOSTAVAX(TM)) in Korean Adults

Choi WS, Choi JH, Choi JY, Eom JS, Kim SI, Pai H, Peck KR, Sohn JW, Cheong HJ

A live attenuated zoster vaccine (ZOSTAVAX(TM), Merck & Co., Inc.) was approved by the Korea Ministry of Food and Drug Safety in 2009. However, the immunogenicity and safety of the...
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Successful Immunoglobulin Treatment in Severe Cryptogenic Organizing Pneumonia Caused by Dermatomyositis

Lee DH, Yeo JH, Kim YI, Gim SJ, Sohn JW, Yhi JY

In connective tissue diseases, autoantibodies cause pulmonary interstitial inflammation and fibrosis, and patients require treatment with an immunosuppressive agent such as a steroid. Dermatomyositis is an incurable, uncommon form of...
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Intrathoracic Desmoid Tumor Presenting as Multiple Lung Nodules 13 Years after Previous Resection of Abdominal Wall Desmoid Tumor

Koo GW, Chung SJ, Kwak JH, Oh CK, Park DW, Kwak HJ, Moon JY, Kim SH, Sohn JW, Yoon HJ, Shin DH, Park SS, Oh YH, Pyo JY, Kim TH

Desmoid tumors are rare soft tissue tumors considered to have locally infiltrative features without distant metastasis until now. Although they are most commonly intraabdominal, very few cases have extra-abdominal locations....
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Clinical Significance of Aberrant Wnt7a Promoter Methylation in Human Non-Small Cell Lung Cancer in Koreans

Kim TH, Moon JY, Kim SH, Paik SS, Yoon HJ, Shin DH, Park SS, Sohn JW

The Wnt signaling pathway has regulatory roles in cell proliferation, differentiation, and polarity. Aberrant Wnt pathway regulation can lead to abnormal cell proliferation and cancer, and loss of Wnt7a expression...
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The Wnt/beta-catenin signaling pathway regulates the development of airway remodeling in patients with asthma

Kwak HJ, Park DW, Seo JY, Moon JY, Kim TH, Sohn JW, Shin DH, Yoon HJ, Park SS, Kim SH

Airway remodeling is a key characteristic of chronic asthma, particularly in patients with a fixed airflow limitation. The mechanisms underlying airway remodeling are poorly understood, and no therapeutic option is...
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A Case of Influenza Associated Fulminant Myocarditis Successfully Treated with Intravenous Peramivir

Baik SH, Jeong HS, Kim SJ, Yoon YK, Sohn JW, Kim MJ

We report the case of a patient with fulminant myocarditis caused by influenza A virus, who presented with acute-onset heart failure and cardiogenic shock and was treated successfully with single...
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Bilious Pleural Infection via Pleurobiliary Fistula Following Percutaneous Transhepatic Gallbladder Drainage

Lee HY, Lee JY, Kim YI, Chang KS, Yhi JY, Moon JY, Kim SH, Kim TH, Sohn JW, Shin DH, Yoon HJ, Park DW

A pleurobiliary fistula is an abnormal communication between the biliary system and the pleural space. It has rarely been reported after percutaneous transhepatic gallbladder drainage (PTGBD). Here, we report the...
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Pulmonary Foreign Body Granulomatosis in Dental Technician

Chung SJ, Koo GW, Park DW, Kwak HJ, Yhi JY, Moon JY, Kim SH, Sohn JW, Yoon HJ, Shin DH, Park SS, Pyo JY, Oh YH, Kim TH

Occupational lung diseases are caused by several toxic substances including heavy metals; however, the exact pathologic mechanisms remain unknown. In the workplace, dental technicians are often exposed to heavy metals...
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A Case of Significant Endobronchial Injury due to Recurrent Iron Pill Aspiration

Kwak JH, Koo GW, Chung SJ, Park DW, Kwak HJ, Moon JY, Kim SH, Sohn JW, Yoon HJ, Shin DH, Park SS, Pyo JY, Oh YH, Kim TH

Gastric mucosal damage by iron pills is often reported. However, iron pill aspiration is uncommon. Oxidation of the impacted iron pill causes bronchial mucosal damage that progresses to chronic bronchial...
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