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Emerging agents for the treatment of metastatic urothelial cancer

Kwon WA, Seo HK

Over the past few decades, platinum-based combination chemotherapy (PBCC) has been the preferred initial therapy for metastatic urothelial cancer (mUC). However, despite a response rate of approximately 50%, a small...
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Survival prognoses of Heng intermediate-risk patients with metastatic renal cell carcinoma treated with immunotherapy or targeted therapy: A real-world, single-center retrospective study

Kim SH, Lee DE, Joung JY, Seo HK, Lee KH, Chung J

PURPOSE: This study aimed to compare progression-free survival (PFS), overall survival (OS), and cancer-specific survival (CSS) in Heng intermediate-risk patients with metastatic renal cell carcinoma (mRCC) treated with first-line immunotherapy...
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Identification of Significant Prognostic Tissue Markers Associated with Survival in Upper Urinary Tract Urothelial Carcinoma Patients Treated with Radical Nephroureterectomy: A Retrospective Immunohistochemical Analysis Using Tissue Microarray

Kim SH, Park WS, Park B, Chung J, Joung JY, Lee KH, Seo HK

Purpose The purpose of this study was to identify prognostic tissue markers for several survival outcomes after radical nephroureterectomy among patients with upper urinary tract urothelial carcinoma using tissue microarray and...
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Oncologic, Perioperative Outcomes of Female Radical Cystectomy: Results from a Multicenter Study in Korea

Shim JS, Seo HK, Ku JH, Jeong BC, Hong B, Kang SH, UCART (Urothelial Cancer-Advanced Research and Treatment Group in Korea) Group

PURPOSE: The lower incidence of bladder cancer among women has led to a lack of information on female radical cystectomy (RC). This study aimed to analyze the characteristics related with...
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Laparoscopy versus Open Nephroureterectomy in Prognostic Outcome of Patients with Advanced Upper Tract Urothelial Cancer: A Retrospective, Multicenter, Propensity-Score Matching Analysis

Kim SH, Song MK, Kim JK, Hong B, Kang SH, Ku JH, Jeong BC, Seo HK, Urothelial Cancer-Advanced Research and Treatment (UCART) Study Group

PURPOSE: The purpose of this study was to compare oncologic outcomes between open nephroureterectomy (ONU) and laparoscopic nephroureterectomy (LNU) in patients with upper tract urothelial carcinoma. MATERIALS AND METHODS: The medical...
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Retrospective Study of the Significant Predictive Role of Inflammatory Degree in Initial and Repeat Prostate Biopsy Specimens for Detecting Prostate Cancer

Kim SH, Park B, Joung JY, Chung J, Seo HK, Lee KH, Park WS

PURPOSE: The purpose of this study was to determine whether histologic inflammation (HI) in initial and repeat prostate biopsy specimens was significantly associated with the detection of prostate cancer. MATERIALS AND...
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Use of docetaxel plus androgen deprivation therapy for metastatic hormone-sensitive prostate cancer in Korean patients: A retrospective study

Kwon WA, Joung JY, Lee JE, Choi SY, Kim SH, Seo HK, Lee KH, Kim CS

PURPOSE: We aimed to evaluate the efficacy and safety of the use of docetaxel plus androgen deprivation therapy (ADT) for metastatic hormone-sensitive prostate cancer (mHSPC) in Korean patients. MATERIALS AND METHODS:...
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Significant clinicopathologic prognostic factors for bladder recurrence, progression, and cancer-specific survival after surgery among patients with upper urinary tract urothelial carcinoma

Kim SH, Song MK, Joung JY, Chung J, Lee KH, Seo HK

PURPOSE: This study aimed to identify prognostic factors for outcomes after radical nephroureterectomy among patients with upper urinary tract urothelial carcinoma (UTUC). MATERIALS AND METHODS: We retrospectively reviewed 184 nonmetastatic cases...
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The Comparison of Oncologic Outcomes between Open and Laparoscopic Radical Nephroureterectomy for the Treatment of Upper Tract Urothelial Carcinoma: A Korean Multicenter Collaborative Study

Kim TH, Hong B, Seo HK, Kang SH, Ku JH, Jeong BC

PURPOSE: We compared oncologic outcomes of patients with upper tract urothelial carcinoma (UTUC) who underwent open nephroureterectomy (ONU) or laparoscopic nephroureterectomy (LNU). MATERIALS AND METHODS: Consecutive cases of ONU and LNU...
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Immune checkpoint inhibitors for urothelial carcinoma

Kim HS, Seo HK

Urothelial carcinoma (UC), originating in the bladder or upper urinary tract, is the most common histological type of cancer. Currently, platinum-based cytotoxic chemotherapy is the standard treatment for metastatic UC...
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Prostatectomy Provides Better Symptom-Free Survival Than Radiotherapy Among Patients With High-Risk or Locally Advanced Prostate Cancer After Neoadjuvant Hormonal Therapy

Kim SH, Song MK, Park WS, Joung JY, Seo HK, Chung J, Lee KH

PURPOSE: The purpose of this study is to compare the radiation therapy (RT) and radical prostatectomy (RP) of high-risk or locally advanced prostate cancer (PC) patients after neoadjuvant hormonal therapy...
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The survival impact of surgical waiting time in patients with resectable pancreatic head cancer

Seo HK, Hwang DW, Park SY, Park Y, Lee SJ, Lee JH, Song KB, Lee YJ, Kim SC

BACKGROUNDS/AIMS: After centralization policy, clinical outcomes have been improved in patients underwent pancreaticoduodenectomy for pancreatic cancer. However, centralization could exacerbate the prolongation of surgical waiting time. This study aims to...
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Two-Year Hospital-Wide Surveillance of Central Line-Associated Bloodstream Infections in a Korean Hospital

Seo HK, Hwang JH, Shin MJ, Kim SY, Song KH, Kim ES, Kim HB

BACKGROUND: Surveillance and interventions of central line-associated bloodstream infections (CLABSIs) had mainly been targeted in intensive care units (ICUs). Central lines are increasingly used outside ICUs. Therefore, we performed a...
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Lifestyle Risk Prediction Model for Prostate Cancer in a Korean Population

Kim SH, Kim S, Joung JY, Kwon WA, Seo HK, Chung J, Nam BH, Lee KH

PURPOSE: The use of prostate-specific antigen as a biomarker for prostate cancer (PC) has been controversial and is, therefore, not used by many countries in their national health screening programs....
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Second Primary Cancer Risk among Kidney Cancer Patients in Korea: A Population-Based Cohort Study

Joung JY, Kwon WA, Lim J, Oh CM, Jung KW, Kim SH, Seo HK, Park WS, Chung J, Lee KH, Won YJ

PURPOSE: Secondary primary cancers (SPCs) commonly arise in patients with renal cell carcinoma (RCC). We designed the present study to estimate the SPC incidence in Korean patients with RCC. MATERIALS AND...
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Current Trends in the Incidence and Survival Rate of Urological Cancers in Korea

Joung JY, Lim J, Oh CM, Jung KW, Cho H, Kim SH, Seo HK, Park WS, Chung J, Lee KH, Won YJ

PURPOSE: This descriptive study assessed the current trends in the incidence of urological cancers and patient survival in Korea. MATERIALS AND METHODS: In this nationwide retrospective observational study based on the...
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Core Competencies for New Nurses

Kim JA, Chu MS, Kwon KJ, Seo HK, Lee SN

PURPOSE: The purpose of this study was to identify core competencies for new nurses and valuate the appropriateness and capability of core competencies. METHODS: Mixed method was applied for the study....
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Prostate Cancer in a Patient with a Family History of BRCA Mutation: a Case Report and Literature Review

Song WH, Kim SH, Joung JY, Park WS, Seo HK, Chung J, Lee KH

One of the most significant risk factors for prostate cancer (PC) is a family history of the disease, with germ-line mutations in the breast cancer predisposition gene (BRCA) 2 conferring...
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The Retrospective Analysis of Prognostic Significance of Smoking Status in Bladder Cancer

Kim SH, Kim S, Suh YS, Kim JK, Joung JY, Chung J, Park WS, Lee KH, Seo HK

PURPOSE: This study aimed to evaluate the prognostic significance of smoking status in muscle invasive bladder cancer (MIBC) and non-MIBC in recurrence-free (RFS), progression-free (PFS), disease-free survival (DFS), and cancer-specific...
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Surgical treatment of mucin-producing cholangiocarcinoma arising from intraductal papillary neoplasm of the intrahepatic bile duct: a report of 2 cases

Baterdene , Hwang S, Lee JW, Jung MJ, Shin H, Seo HK, Kim MH, Lee SK

Intraductal papillary neoplasms of the bile duct (IPNB) leads to malignant transformation and mucin production. Herein, we presented two cases of mucin-producing IPNB with obstructive jaundice who underwent resection of...
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