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Phospholipase C Beta 2 Protein Overexpression Is a Favorable Prognostic Indicator in Newly Diagnosed Normal Karyotype Acute Myeloid Leukemia

Park MS, Lee YE, Kim HR, Shin JH, Cho HW, Lee JH, Shin MG

Phospholipase C beta 2 (PLC-β2) regulates various essential functions in cell signaling, differentiation, growth, and mobility. We investigated the clinical implications of PLC-β2 protein expression in newly diagnosed normal karyotype...
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Delirium-Related Knowledge, Caregiving Performance, Stress Levels, and Mental Health of Family Caregivers of Terminal Cancer Patients with Delirium in a Hospice Care Unit

Jung MH, Park MH, Kim SJ, Ra JR

Purpose: The purpose of this study was to examine the knowledge, caregiving performance, stress levels, and mental health of family caregivers of terminal cancer patients with delirium, insofar as these...
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A Case Report of Cholangiocarcinoma Arising from a Biliary Adenofibroma: Radiologic Findings and Review of Literature

Lim HJ, Park MS, Park YN, Kim SI, Kim YE, Hwang CH

Biliary adenofibromas are rare biliary epithelial tumors that are classified as benign. Nevertheless, some cases have been reported to show malignant transformations. The radiologic findings of biliary adenofibromas and their...
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Evaluation of the Barricor Tube in 28 Routine Chemical Tests and Its Impact on Turnaround Time in an Outpatient Clinic

Moon SY, Lee HS, Park MS, Kim IS, Lee SM

Background: We recently introduced the Barricor (BD, Franklin Lakes, NJ, USA) plasma separation tube, which uses a mechanical separator instead of a gel. We evaluated the effects of using the...
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Multifactorial Traits of SARS-CoV-2 Cell Entry Related to Diverse Host Proteases and Proteins

You J, Seok JH, Joo M, Bae JY, Kim JI, Park MS, Kim K

The most effective way to control newly emerging infectious disease, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, is to strengthen preventative or therapeutic public health strategies...
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The Occupational Characteristics and Health Status of Workers in Geographically Isolated and Confined Areas in the Republic of Korea

Ahn J, Lee J, Lee SH, Park MY, Lee W

Background: This study investigates the safety and health status of geographically isolated and confined workers. Methods: This study was conducted in Baekryeong Island in Korea in 2020. The agestandardized prevalence ratios...
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Efficacy and tolerability of mirabegron compared with solifenacin for children with idiopathic overactive bladder: A preliminary study

Kim SC, Park M, Chae C, Yoon JH, Kwon T, Park S, Moon KH, Cheon SH, Park S

Purpose: To compare the efficacy and tolerability of mirabegron and solifenacin in pediatric patients with idiopathic overactive bladder (OAB) and to identify factors affecting OAB symptom improvement after treatment. Materials and...
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Antiviral Efficacy of Pralatrexate against SARS-CoV-2

Bae JY, Lee GE, Park H, Cho J, Kim J, Lee J, Kim K, Kim JI, Park MS

Novel coronavirus (SARS-CoV-2) has caused more than 100 million confirmed cases of human infectious disease (COVID-19) since December 2019 to paralyze our global community. However, only limited access has been...
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Risk Factor of Mood Disorder Development in Breast Cancer Survivors

Park MA, Seo HJ

Objective : The questionnaire-based study model has a problem in that there is no information on diseases and drugs to determine the association between mood disorders and the severity of...
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Tumors of the Pleura and Lung Developed 17 Years after Allogeneic Bone Marrow Transplantation for Childhood Acute Myelomonocytic Leukemia: Synovial Sarcoma Mimicking Malignant Mesothelioma

Lee JA, Cho B, Shin SA, Park SY, Park M, Park HJ

Synovial sarcoma occurring in the pleura and lung is extremely rare. We report a case of pleuropulmonary synovial sarcoma as a second malignant neoplasm. The patient had been diagnosed with...
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Myelodysplastic syndrome with genetic predisposition

Park M

Myelodysplastic syndrome (MDS) refers to a heterogeneous group of clonal blood disorders characterized by ineffective hematopoiesis, cytopenia, dysplasia, and an increased risk of acute myeloid leukemia (AML). A growing number...
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Current Status of Korean Red Cross HLA-Matched Platelet Donor Registry

Kim Y, Lim AH, Kim TE, Jung CH, Park M, Seon J, Youn KW, Lee AG, Youn M

HLA-matched platelet transfusion is required for patients with platelet refractoriness due to HLA alloimmunity. From 2013 to 2019, the Korean Red Cross has recruited 4,080 donors for HLA-matched platelets. The...
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Clinical Outcomes Following Letrozole Treatment according to Estrogen Receptor Expression in Postmenopausal Women: LETTER Study (KBCSG-006)

Ahn SG, Nam SJ, Ahn SH, Jung Y, Park HK, Lee SJ, Kang SS, Han W, Park KH, Park YL, Lee J, Youn HJ, Kim JH, Yoo Y, Song JY, Ko BK, Gwak G, Chung MS, Kim SY, Cho SH, Kim D, Chang MC, Moon BI, Kim LS, Kim SJ, Park MH, Kim TH, Cho J, Lim CW, Bae YT, Gong G, Bae YK, Lee A, Jeong J

Purpose: In this trial, we investigated the efficacy and safety of adjuvant letrozole for hormone receptor (HR)-positive breast cancer. Here, we report the clinical outcome in postmenopausal women with HR-positive...
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Effects of Smoking on Long-Term Clinical Outcomes and Lung Cancer in Patients with Acute Myocardial Infarction

Lee SN, Choi IJ, Lim S, Choo EH, Hwang BH, Kim CJ, Park MW, Lee JM, Park CS, Kim HY, Yoo KD, Jeon DS, Youn HJ, Chung WS, Kim MC, Jeong MH, Ahn Y, Chang K

Background and Objectives: Smoking is well-established as a risk factor for coronary artery disease. However, recent studies demonstrated favorable results, including reduced mortality, among smokers, which are referred to as...
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Effects of Recombinant Human Growth Hormone on the Onset of Puberty, Leydig Cell Differentiation, Spermatogenesis and Hypothalamic KISS1 Expression in Immature Male Rats

Huh K, Nah WH, Xu Y, Park MJ, Gye MC

Purpose: Recombinant human growth hormone (rhGH) has been used to treat short stature and rhGH-related syndromes. However, there are concerns that rhGH-treatment may cause precocious puberty. We investigated the effects...
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Radiologic Evaluation for Resectability of Pancreatic Adenocarcinoma

Hwang SH, Park MS

Imaging studies play an important role in the detection, diagnosis, assessment of resectability, staging, and determination of patient-tailored treatment options for pancreatic adenocarcinoma. Recently, for patients diagnosed with borderline resectable...
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Influenza Vaccine Effectiveness in Children at the Emergency Department during the 2018-2019 Season: the First Season School-aged Children Were Included in the Korean Influenza National Immunization Program

Yoon Y, Choi Js, Park M, Cho H, Park M, Huh HJ, Kim YJ, Son MH

Background: For the 2018–2019 season, the national influenza immunization program expanded to cover children aged from 6 months to 12 years in Korea. This study aimed to analyze vaccine effectiveness...
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Education, Role, and Prospects of Advanced Practice Nurses in Hospice and Palliative Care in South Korea

Kwon SH, Park MH, Kim HS

Hospice palliative care refers to holistic care provided by an interdisciplinary team aimed at improving the quality of life of patients suffering from life-threatening diseases and their families. Among interdisciplinary...
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Establishment of Pediatric Reference Intervals for Routine Laboratory Tests in Korean Population: A Retrospective Multicenter Analysis

Sung JY, Seo JD, Ko DH, Park MJ, Hwang SM, Oh S, Chun S, Seong MW, Song J, Song SH, Park SS

Background: Reference intervals defined for adults or children of other ethnicities cannot be applied in the evaluation of Korean pediatric patients. Pediatric reference intervals are difficult to establish because children...
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The Effects of Robot-Assisted Rehabilitation on the Gait Ability of Stroke Patients with Hemiplegia: A Mixed Methods Research Study

Park MG, Ha YM, Cho HJ, Jeon MY

Purpose: This study used a mixed methods research design in an attempt to verify the effects of robot-assisted rehabilitation on the gait ability of stroke patients with hemiplegia, and thereby...
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