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The First Korean Case of NUP98-NSD1 and a Novel SNRK-ETV6 Fusion in a Pediatric Therapy-related Acute Myeloid Leukemia Patient Detected by Targeted RNA Sequencing

Lim HJ, Lee JH, Lee YE, Baek HJ, Kook H, Park JH, Lee SY, Choi HW, Choi HJ, Kee SJ, Shin JH, Shin MG

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Prevalence and Incidence of Dementia in South Korea: A Nationwide Analysis of the National Health Insurance Service Senior Cohort

Jang JW, Park JH, Kim S, Lee SH, Lee SH, Kim YJ

Background and Purpose Dementia is rapidly becoming more common in the elderly population of South Korea, and there are regional difference in its demographics. This study investigated the trajectories in...
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Effect of pregabalin on nociceptive thresholds and immune responses in a mouse model of incisional pain

Park JH, Cho SH, Kim R, Na SH, Kang Es, Yeom My, Jang Y

Background: It is known that some analgesics as well as pain can affect the immune system. The aim of this study was to investigate the analgesic effect and immunomodulation of...
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Combination Treatment of Intra/Perilesional Botulinum Toxin-A Injection and Ablative Fractional Laser for Better Clinical Outcomes of Hypertrophic Fibrotic Thyroidectomy Scars Following Fractional Ablative Laser Resurfacing

Byun HJ, Park JH, Lee JH

Background: Recent reports have shown that intralesional botulinum toxin type-A (BTX-A) works on scar cosmesis. Objective: To evaluate the clinical efficacy of combination treatment of laser and BTX-A injection and compare...
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Characterization of the Onychomatricodermis Containing Onychofibroblasts of the Nail Unit : Histology, Immunohistochemistry, and Electron Microscopic Study

Lee D, Abudureyimu G, Park JH, Jang KT, Kwon GY, Shim JS

Background: We recently discovered the presence of specialized nail mesenchyme below the nail matrix and designated it as onychomatricodermis. Objective: We did further research to characterize the histologic, histochemical, immunohistochemical...
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Neonatal Outcomes according to the Latent Period from Membrane Rupture to Delivery among Extremely Preterm Infants Exposed to Preterm Premature Rupture of Membrane: a Nationwide Cohort Study

Park JH, Bae JG, Chang YS

Background: In accordance with the guidelines for the expectant management of women exposed to previable preterm premature rupture of membrane, we compared neonatal outcomes according to the latent period from...
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Ortner's Syndrome Discovered by a Routine Echocardiographic Examination: a Huge Aneurysmal Dilatation of the Aortic Arch as a Cause of Hoarseness

Jeong JO, Park YS, Park JH

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Apoptotic activity of demethoxycurcumin in MG-63 human osteosarcoma cells

Kang KR, Kim JS, Kim TH, Seo JY, Park JH, Chun HS, Yu SK, Kim HJ, Kim CS, Kim DK

Demethoxycurcumin (DMC), which is a curcuminoid found in turmeric, has anti-proliferative effects on cancer cells. However, the effect of DMC on osteosarcoma has not been established. The aim of this...
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Alpha-lipoic acid protects human dopaminergic neuronal cells against hydrogen peroxide-induced cell injury by inhibiting autophagy and apoptosis

Kang KR, Kim JS, Kim TH, Seo JY, Lim H, Park JH, Yang KY, Yu SK, Kim HJ, Kim CS, Chun HS, Lee DS, Park JC, Kim DK

Alpha-lipoic acid (ALA) is a naturally occurring antioxidant and has been previously used to treat diabetes and cardiovascular disease. However, the autophagy effects of ALA against oxidative stress-induced dopaminergic neuronal...
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Perception of Medical Students and Doctors on Osteology Education

Park JH, Lee SH, Jeon JC, Choi WI, Kim GM, Lee JH

Anatomy is being taught as a compulsory subject in various health care-related occupations. In anatomy, osteology is learning the names of bones and offers detailed structure of each bone and...
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Frequency of Benign Variants Associated with Hematologic Malignancy in the Catalogue of Somatic Mutations in Cancer

Park KJ, Park JH

Background: The presence of benign variants in mutation databases is a well-documented pitfall when interpreting clinical variants associated with hematologic malignancy. The aim of this study was to investigate the...
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Effects of Wearable Powered Exoskeletal Training on Functional Mobility, Physiological Health and Quality of Life in Non-ambulatory Spinal Cord Injury Patients

Kim HS, Park JH, Lee HS, Lee JY, Jung JW, Park SB, Hyun DJ, Park S, Yoon J, Lim H, Choi YY, Kim MJ

Background: Spinal cord injury (SCI) is a serious clinical condition that impacts a patient's physical, psychological, and socio-economic status. The aim of this pilot study was to evaluate the effects...
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Machine-Learning-Based Approach to Differential Diagnosis in Tuberculous and Viral Meningitis

Jeong YS, Jeon M, Park JH, Kim MC, Lee E, Park SY, Lee YM, Choi S, Park SY, Park KH, Kim SH, Jeon MH, Choo EJ, Kim TH, Lee MS, Kim T

Background: Tuberculous meningitis (TBM) is the most severe form of tuberculosis, but differentiating between the diagnosis of TBM and viral meningitis (VM) is difficult. Thus, we have developed machine-learning modules...
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Compositional and Functional Changes in the Gut Microbiota in Irritable Bowel Syndrome Patients

Lee SM, Kim N, Yoon H, Kim YS, Choi SI, Park JH, Lee DH

Background/Aims: This study aimed to characterize the changes in the gut microbiota of irritable bowel syndrome (IBS) patients and to investigate the consequent alterations in bacterial functions. Methods: We performed 16S...
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Investigation for Shoulder Kinematics Using Depth Sensor-Based Motion Analysis System

Lee I, Park JH, Son DW, Cho Y, Ha SH, Kim E

Purpose: The purpose of this study was to analyze the motion of the shoulder joint dynamically through a depth sensor-based motion analysis system for the normal group and patients group...
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Massive hemothorax after central venous catheter insertion in a patient with multiple trauma

Park JH, Song J, Oh Pw

Central venous catheter (CVC) insertion is commonly used in the operating room and intensive care unit to monitor central venous pressure and secure an intravenous route to deliver medications and...
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Clinical efficacy of respiratory virus detection by using the FilmArray method in children admitted with respiratory infection

Lee HJ, Park JH, Kim JM, Kim JH, Baek HS

Purpose: Respiratory virus infection is a common cause of hospitalization in children. Rapid testing for respiratory viruses, such as the FilmArray method, can be clinically useful. However, insufficient evidence exists...
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Dysphagia in Wilson’s Disease: A Case Report of One-Year Follow-Up

Kim D, Park YG, Park JH, Park J

Wilson’s disease (WD) is a genetic disease caused by an ATP7B gene mutation. Although dysphagia is known as a neurological manifestation of WD, clinical case reports with post-treatment long-term follow-up...
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Changes in Cecal Microbiota and Short-chain Fatty Acid During Lifespan of the Rat

Choi SI, Son JH, Kim N, Kim YS, Nam RH, Park JH, Song CH, Yu JE, Lee DH, Yoon K, Min H, Kim YR, Seok YJ

  • KMID: 2510071
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):134-146.
  • doi: 10.5056/jnm20148
Background/Aims The gut microbiota regulates intestinal immune homeostasis through host-microbiota interactions. Multiple factors affect the gut microbiota, including age, sex, diet, and use of drugs. In addition, information on gut microbiota...
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Gamma-aminobutyric acid-salt attenuated high cholesterol/high salt diet induced hypertension in mice

Son M, Oh S, Lee HS, Choi J, Lee BJ, Park JH, Park CH, Son KH, Byun K

Excessive salt intake induces hypertension, but several gamma-aminobutyric acid (GABA) supplements have been shown to reduce blood pressure. GABAsalt, a fermented salt by L. brevis BJ20 containing GABA was prepared...
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