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Surgical Strategies for Achilles Tendinopathy

Park HW

The surgical treatment of Achilles tendinopathy can be considered after the failure of conservative treatment, and the surgical methods may be divided into two groups; treatments for insertional and non-insertional...
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Seven Principles of Quarantine for the COVID-19 Pandemic

Park HW

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Tumor Spheroids of an Aggressive Form of Central Neurocytoma Have Transit-Amplifying Progenitor Characteristics with Enhanced EGFR and Tumor Stem Cell Signaling

Shin HY, Han KS, Park HW, Hong YH, Kim Y, Moon HE, Park KW, Park HR, Lee CJ, Lee K, Kim SJ, Heo MS, Park SH, Kim DG, Paek SH

  • KMID: 2515812
  • Exp Neurobiol.
  • 2021 Apr;30(2):120-143.
  • doi: 10.5607/en21004
Central neurocytoma (CN) has been known as a benign neuronal tumor. In rare cases, CN undergoes malignant transformation to glioblastomas (GBM). Here we examined its cellular origin by characterizing differentiation...
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Lung function decline in adult; when does it begin?

Park HW

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Incidence of Postnatal CMV Infection among Breastfed Preterm Infants: a Systematic Review and Meta-analysis

Park HW, Cho MH, Bae SH, Lee R, Kim KS

Background: We performed a systematic review and meta-analysis to evaluate the incidence of breast milk-acquired cytomegalovirus (CMV) infection in preterm infants born to CMVseropositive mothers. Methods: PubMed, Embase, and Cochrane Library...
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Are Magnetic Resonance Imaging Findings of Ankle Instability Always Correlated with Operative and Physical Examination Findings?

Park Hw

Physical examination and surgical findings and symptoms are often inconsistent with magnetic resonance imaging (MRI) findings when diagnosing chronic ankle lateral ligament instability, and confirmed surgical findings are used as...
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Right Ventricular Longitudinal Conduction Delay in Patients with Brugada Syndrome

Yoon N, Jeong HK, Lee KH, Park HW, Cho JG

Background: The mechanism of Brugada syndrome (BrS) is still unclear, with different researchers favoring either the repolarization or depolarization hypothesis. Prolonged longitudinal activation time has been verified in only a...
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Ethnic Difference of Thrombogenicity in Patients with Cardiovascular Disease: a Pandora Box to Explain Prognostic Differences

Kim HK, Tantry US, Park HW, Shin ES, Geisler T, Gorog DA, Gurbel PA, Jeong YH

Arterial and venous atherothrombotic events are finely regulated processes involving a complex interplay between vulnerable blood, vulnerable vessel, and blood stasis. Vulnerable blood (‘thrombogenicity’) comprises complex interactions between cellular components...
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Sonographic Appearance of Steatocystoma: An Analysis of 14 Pathologically Confirmed Lesions

Yoon H, Kang Y, Park H, Ahn JM, Lee E, Lee JW, Kang HS

Purpose To evaluate the ultrasonographic characteristics of steatocystomas focusing on the features that aid in differentiating them from epidermal inclusion cysts and lipomas. Materials and Methods The ultrasonographic findings of 14...
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Genetic Signatures of Acute Asthma Exacerbation Related With Ineffective Response to Corticosteroid

Kang MG, Lee HS, Tantisira , Park HW

Purpose: Acute exacerbation (AE) is an important domain of asthma management and may be related with ineffective response to corticosteroid. This study aimed to find mechanisms of AE using genome-wide...
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Orbital Apex Syndrome Caused by Co-infection of Actinomyces with Invasive Fungal Sinusitis

Yoon JS, Hong SR, Park HW

Purpose: We report a case of orbital apex syndrome caused by co-infection of Actinomyces and Aspergillus invasive fungal sinusitis. Case summary: An 87-year-old female visited our clinic for decreased visual acuity...
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Dynamic Change of Ischemic Mitral Regurgitation in a Patient with Acute Coronary Syndrome

Kim HR, Kang MG, Kim K, Park HW, Hwang JY, Park JR

Ischemic mitral regurgitation (IMR) is commonly known as a chronic complication of left ventricular remodeling due to coronary artery disease. Acute IMR after coronary artery disease, such as acute myocardial...
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Clinical Results of Surgical Treatment with Minimally Invasive Percutaneous Plate Osteosynthesis for Displaced Intra-articular Fractures of Calcaneus

Suh JW, Yang JH, Park HW

Purpose: This study evaluated the clinical results of surgical treatment with minimally invasive plate osteosynthesis for treating displaced intra-articular fractures of the calcaneus in comparison with conventional lateral extensile approach...
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Factors for Survival and Complications of Malignant Bone Tumor Patients with a Total Femoral Replacement

Cho WH, Jeon DG, Song WS, Park HS, Nam HS, Kim KH

Purpose: Total femoral replacement (TFR) is an extreme form of limb salvage. Considering the rarity of this procedure, reports have focused on the complications and a proper indication is unclear....
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Defining Association between COVID-19 and the Multisystem Inflammatory Syndrome in Children through the Pandemic

Kim YJ, Park H, Choi YY, Kim YK, Yoon Y, Kim KR, Choi EH

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Risk Factors for Acute Exacerbations in Elderly Asthma: What Makes Asthma in Older Adults Distinctive?

Sohn KH, Song WJ, Park JS, Park HW, Kim TB, Park CS, Cho SH, on behalf of the Elderly Asthma Cohort in Korea Group

PURPOSE: Asthma in the elderly (EA; ≥ 65 years of age) is increasing, adding a heavy socioeconomic burden to the healthcare system. However, little is known about risk factors associated...
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Understanding the Molecular Mechanisms of Asthma through Transcriptomics

Park HW, Weiss ST

The transcriptome represents the complete set of RNA transcripts that are produced by the genome under a specific circumstance or in a specific cell. High-throughput methods, including microarray and bulk...
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Sestrin2 Mediates IL-4-induced IgE Class Switching by Enhancing Germline ε Transcription in B Cells

Shim YS, Lee S, Park HW, Park SR

Sestrin2 (Sesn2), a metabolic regulator, accumulates in response to a diverse array of cellular stresses. Sesn2 regulates cellular metabolism by inhibiting the mammalian target of rapamycin complex 1 through the...
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Current Anticoagulant Usage Patterns and Determinants in Korean Patients with Nonvalvular Atrial Fibrillation

Ha HS, Kim J, Lee YS, Kim TH, Lee JM, Park J, Park JK, Kang KW, Shim J, Uhm JS, Park HW, Cha MJ, Choi EK, Kim J, Kim JB, Kim C, Joung B

PURPOSE: Stroke prevention in patients with atrial fibrillation (AF) is influenced by many factors. Using a contemporary registry, we evaluated variables associated with the use of warfarin or direct oral...
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Impact of Anticoagulation Intensity in Korean Patients with Atrial Fibrillation: Is It Different from Western Population?

Lee KH, Cho JG, Lee N, Cho KH, Jeong HK, Park H, Kim Y, Cho JY, Kim MC, Sim DS, Yoon HJ, Yoon N, Kim KH, Hong YJ, Park HW, Ahn Y, Jeong MH, Park JC

BACKGROUND AND OBJECTIVES: Although anticoagulation with warfarin is recommended as an international normalized ratio (INR) of prothrombin time between 2.0 and 3.0 and mean time in the therapeutic range (TTR)...
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