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Immobilization Effect and Abdominal Pressure of Newly-Developed Lumbosacral Spinal Orthosis during Task Performance

Jeon KS, Yang HS, Jang SW, Shin HD, Lee Yk, Lee Y, Lee SBN, Ahn DY, Sim WS, Cho M, Cho KJ, Park DB, Park KS

Objective: We evaluated the efficacy of a newly-developed spinal orthoses (V-LSO) by comparing the stabilizing effect, abdominal pressure, and comfort of 3 different semirigid LSOs (classic LSO, V-LSO, and CybertechⓇ...
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Piperlongumine suppressed osteoclastogenesis in RAW264.7 macrophages

Jin SM, Kang HM, Park DB, Yu SB, Kim IR, Park BS

Piperlongumine (PL) is a natural product found in long pepper (Piper longum). The pharmacological effects of PL are well known, and it has been used for pain, hepatoprotection, and asthma...
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Luteolin Induces Apoptosis via Mitochondrial Pathway and Inhibits Invasion and Migration of Oral Squamous Cell Carcinoma by Suppressing Epithelial-Mesenchymal Transition Induced Transcription Factors

Park BS, Kil JJ, Kang HM, Yu SB, Park DB, Park JA, Kim IR

Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy. Numerous therapies have been proposed for its cure. Research is continually being conducted to develop new forms...
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Nobiletin attenuates neurotoxic mitochondrial calcium overload through K⁺ influx and ΔΨ(m) across mitochondrial inner membrane

Lee JH, Amarsanaa , Wu J, Jeon SC, Cui Y, Jung SC, Park DB, Kim SJ, Han SH, Kim HW, Rhyu IJ, Eun SY

Mitochondrial calcium overload is a crucial event in determining the fate of neuronal cell survival and death, implicated in pathogenesis of neurodegenerative diseases. One of the driving forces of calcium...
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Icaritin, a Flavonoid Derived from the Herb Epimedium, Promotes Osteogenic Differentiation of MC3T3-E1 Cells

Park DB, Lee HS, Ko SH

Osteoporosis is a metabolic bone disease that is characterized by low bone mass resulting from an increase in bone resorption relative to bone formation. The most current therapies for osteoporosis...
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Metformin Promotes Apoptosis but Suppresses Autophagy in Glucose-Deprived H4IIE Hepatocellular Carcinoma Cells

Park DB

BACKGROUND: Metformin, a well-known anti-diabetic drug, has gained interest due to its association with the reduction of the prevalence of cancer in patients with type 2 diabetes and the anti-proliferative...
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The Effect of Metformin Treatment on CRBP-I Level and Cancer Development in the Liver of HBx Transgenic Mice

Kim JH, Alam MM, Park DB, Cho M, Lee SH, Jeon YJ, Yu DY, Kim TD, Kim HY, Cho CG, Lee DH

Retinoids regulate not only various cell functions including proliferation and differentiation but also glucose and lipid metabolism. After we observed a marked up-regulation of cellular retinol-binding protein-I (CRBP-I) in the...
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Efficacy and Safety of Paliperidone Extended Release in Schizophrenia Patients Requiring a Switch in Antipsychotic Medication by Switching Previous Antipsychotics to Paliperidone Extended Release

Moon YS, Na KS, Kim CE, Kim YS, Yoon JS, Ahn YM, Jung HY, Yu BH, Jeon YW, Lee SK, Seok JH, Ham BJ, Park DB, Kim H, Lee BW, Hong CH, Kim JW, Han JH

  • KMID: 2287497
  • Korean J Psychopharmacol.
  • 2012 Jul;23(3):97-106.
OBJECTIVE: This study aimed to evaluate the clinical efficacy, safety, and tolerability of paliperidone extended release (ER) in patients with schizophrenia by switching previous antipsychotics to paliperidone ER. METHODS: An open-label,...
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Effects of Smoking on Drinking Behavior

Noh DH, Han DH, Na C, Min KJ, Park DB

  • KMID: 2341934
  • J Korean Neuropsychiatr Assoc.
  • 2011 May;50(3):222-227.
OBJECTIVES: This survey study was conducted to investigate the effect of smoking on drinking alcohol, depression, anxiety and impulsiveness. METHODS: The survey participants were 925 residents over 20 years of age...
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Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome

Park DB

  • KMID: 1462864
  • J Korean Soc Pediatr Endocrinol.
  • 2010 Aug;15(2):77-84.
Non-alcoholic fatty liver disease (NAFLD), the most common liver disease, represents a spectrum of disease including steatohepatitis, fibrosis, and irreversible cirrhosis. Although a "benign" condition, NAFLD is a risk factor...
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Insecure Attachment and Impulsivity-Inattention Problem in Adolescent with a High Risk of Substance or Internet Addiction

Cho SI, Lee YS, Baek HT, Han DH, Kee BS, Park DB, Ko BJ

  • KMID: 2341770
  • J Korean Neuropsychiatr Assoc.
  • 2010 Jul;49(4):393-400.
OBJECTIVES: This study was done in adolescents with a high risk of substance or internet addiction in order to confirm the assumption that insecure attachment formation and impulsivity-inattention problems are...
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The Relationships between Online Game Player Biogenetic Traits, Playing Time, and the Genre of the Game Being Played

Kim JW, Han DH, Park DB, Min KJ, Na C, Won SK, Park GN

  • KMID: 2315860
  • Psychiatry Investig.
  • 2010 Mar;7(1):17-23.
OBJECTIVE: Psychobiological traits may be associated with excessive Internet use. This study assessed the relationships between biogenetic traits, the amount of time spent in online game playing, and the genre...
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The Association of Cognitive Dysfunction with White Matter Hyperintensity in Alzheimer's Disease and Mild Cognitive Impairment

Yoon SG, Park DB, Na C, Lee YS, Min KJ, Han DH, Choi TY, Ahn YK, Na HI, Kee BS

  • KMID: 2341556
  • J Korean Neuropsychiatr Assoc.
  • 2009 Jul;48(4):287-293.
OBJECTIVES : We investigated the relationship between periventricular and deep white matter hyperintensity and cognitive function in Alzheimer's disease (AD) and mild cognitive impairment (MCI). METHODS : T2-weighted MRI scans were...
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Serum S100B Protein in Medication-Free Schizophrenic Patients

Jin SN, Park DB, Kim HR, Baek HT

  • KMID: 2299979
  • Korean J Biol Psychiatry.
  • 2007 Aug;14(3):177-183.
OBJECTIVES: Previous studies have suggested that S100B protein play an important role in the pathogenesis and progress of schizophrenia. In the present study, we evaluate the serum levels of S100B...
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Ventriculostomy-Associated Infection : Analysis of Risk Factors and the Venue of External Ventricular Drainage

Choi JM, Cho DS, Jin SC, Kim SH, Park DB, Kim YR

  • KMID: 2143909
  • Korean J Cerebrovasc Surg.
  • 2007 Mar;9(1):55-59.
OBJECTIVE: The purpose of this study is to evaluate the risk factors for ventriculostomy-associated infections (VAI) and to examine the differences among VAI according to the venue of catheter placement...
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Mechanism of 2-Deoxy-D-ribose-induced Damage in Pancreatic beta-cells

Koh G, Woo JT, Lee DH, Oh S, Kim SW, Kim JW, Kim YS, Park DB

BACKGROUND: Mechanism for glucose toxicity is known to be an increased oxidative stress produced by multiple pathways. In our previous report, 2-deoxy-d-ribose (dRib) promoted apoptosis by increasing oxidative stress in...
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Outcome of Aneurysmal Subarachnoid Hemorrhage Patients with Hunt-Hess Grade III

Choi SH, Hwang SK, Lim YW, Cho DS, Park DB, Kim SH

  • KMID: 2256659
  • Korean J Cerebrovasc Surg.
  • 2006 Sep;8(3):184-189.
OBJECT: We designed this study to bring the outcome and the outcome predictors of Hunt-Hess grade III patients to light, and to be aid in determining treatment protocol of such...
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Study of Factors associated with Neurological Outcome in Traumatic Subarachnoid Hemorrhage

Shin JH, Hwang SK, Cho DS, Kim SH, Park DB

OBJECTIVE: The goal of this study were to identify the factors that may predict the outcome of subarachnoid hemorrhage (tSAH) patients, and to assist in the management of their treatment. METHODS:...
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Study of Factors Associated with Neurological Outcome in Traumatic Subarachnoid Hemorrhage: Clinical Analysis

Hwang SK, Cho DS, Kim SH, Park DB

No abstract available in English.
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Validity and Reliability of the Korean Version of the Hamilton Depression Rating Scale(K-HDRS)

Yi JS, Bae SO, Ahn YM, Park DB, Noh KS, Shin HK, Woo HW, Lee HS, Han SI, Kim YS

  • KMID: 2341114
  • J Korean Neuropsychiatr Assoc.
  • 2005 Jul;44(4):456-465.
OBJECTIVES: The reliability and validity of the Korean version of Hamilton Depression Rating Scale (K-HDRS) were examined in Korean patients depressive symptoms. METHODS: 33 inpatients and 70 outpatients diagnosed as major...
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