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Efficacy of palonosetron plus dexamethasone in preventing chemotherapy-induced nausea and emesis in patients receiving carboplatin-based chemotherapy for gynecologic cancers: a phase II study by the West Japan Gynecologic Oncology Group (WJGOG 131)

Nishio S, Aihara S, Shimokawa , Fujishita , Taniguchi , Hachisuga , Yanazume S, Kobayashi , Murakami F, Numa F, Kotera K, Okura N, Toki N, Yokoyama M, Ushijima K

OBJECTIVE: Palonosetron is effective for the management of acute and delayed chemotherapy-induced nausea and vomiting (CINV). While emetogenic carboplatin-based chemotherapy is widely used to treat gynecologic cancers, few studies have...
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Identification of appropriate cone length to avoid positive cone margin in high grade cervical intraepithelial neoplasia

Kawano K, Tsuda N, Nishio S, Yonemoto K, Tasaki K, Tasaki R, Ushijima K

OBJECTIVE: To identify key factors for predicting positive cone margin and appropriate cone length. METHODS: We retrospectively reviewed the margin status of patients who received conization with high grade cervical intraepithelial...
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Epithelial borderline ovarian tumor: Diagnosis and treatment strategy

Ushijima K, Kawano K, Tsuda N, Nishio S, Terada A, Kato H, Tasaki K, Matsukuma

Epithelial borderline ovarian tumors (BOT) are distinctive from benign tumors and carcinoma. They occur in younger women more often than carcinoma, and there is some difficulty making correct diagnosis of...
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Prevention of lymphocele development in gynecologic cancers by the electrothermal bipolar vessel sealing device

Tsuda N, Ushijima K, Kawano K, Takemoto S, Nishio S, Sonoda G, Kamura T

OBJECTIVE: A number of new techniques have been developed to prevent lymphocele formation after pelvic lymphadenectomy in gynecologic cancers. We assessed whether the electrothermal bipolar vessel sealing device (EBVSD) could...
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p16INK4a immunohistochemistry is a promising biomarker to predict the outcome of low grade cervical intraepithelial neoplasia: comparison study with HPV genotyping

Nishio S, Fujii T, Nishio H, Kameyama K, Saito M, Iwata T, Kubushiro , Aoki D

OBJECTIVE: In cervical intraepithelial neoplasia (CIN), p16INK4a immunohistochemistry has been reported to be a useful diagnostic biomarker. However, limited information is available about the association between the p16INK4a immunohistochemistry and...
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Concurrent chemoradiotherapy with low-dose daily cisplatin for high risk uterine cervical cancer: a long-term follow-up study

Ushijima K, Fujiyoshi , Kawano K, Tsuda N, Nishio S, Eto H, Kamura T

OBJECTIVE: To evaluate the clinical efficacy of concurrent chemoradiotherapy (CCRT) using daily low-dose cisplatin for cervical cancer. METHODS: Fifty-one patients with locally advanced cervical cancer (FIGO stage IB2, bulky IIA, IIB-IVA)...
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Controversies surrounding type III radical abdominal hysterectomy and its procedure using new instruments

Ushijima K, Takemoto S, Kawano K, Nishio S, Terada A, Tsuda N, Sonoda G, Ota SI, Kamura T

Type III radical abdominal hysterectomy (RAH) is standard care for early stage cervical cancer. For the past few decades, there has been a remarkable shift from surgery to radiation, in...
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