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Reduced Temporal Activation During a Verbal Fluency Task is Associated with Poor Motor Speed in Patients with Major Depressive Disorder

Kiriyama T, Tanemura R, Nakamura Y, Takemoto C, Hashimoto M, Utsumi H

Objective Substantial research has revealed cognitive function impairments in patients with major depressive disorder (MDD). However, the relationship between MDD cognitive function impairment and brain activity is yet to be...
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High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo

Ikeda Y, Sato S, Yabuno A, Shintani D, Ogasawara A, Miwa M, Zewde M, Miyamoto T, Fujiwara K, Nakamura Y, Hasegawa K

Objective: Maternal embryonic leucine zipper kinase (MELK) is receiving an attention as a therapeutic target in various types of cancers. In this study, we aimed to evaluate the prognostic significance...
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Additive effects of eldecalcitol in poorly responding long-term bisphosphonate treatment for osteoporosis

Kamimura M, Ikegami S, Mukaiyama , Koiwai H, Nakamura Y, Taguchi A, Kato H

OBJECTIVES: We examined whether eldecalcitol (ELD) provided additive bone mineral density (BMD) and bone turnover marker gains in patients undergoing long-term bisphosphonate (BP) usage, especially in osteoporotic individuals exhibiting a...
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Additive effect of Lactobacillus acidophilus L-92 on children with atopic dermatitis concomitant with food allergy

Nakata J, Hirota T, Umemura H, Nakagawa T, Kando N, Futamura M, Nakamura Y, Ito K

BACKGROUND: Atopic dermatitis (AD) in infants is often related to food allergies (FA). The beneficial effects of lactic acid bacteria towards allergic diseases have been reported, but there are few...
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Effects of monthly minodronate with or without eldecalcitol addition in osteoporosis patients with rheumatoid arthritis: An 18-month prospective study

Suzuki T, Nakamura Y, Kato H

OBJECTIVES: Increasing bone mineral density (BMD) to reduce fracture risk is a primary goal of osteoporosis treatment. This prospective, observational study evaluates the effects of monthly minodronate (MIN; 50 mg)...
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Efficacy, safety, and compliance of ibandronate treatment for 3 years in postmenopausal Japanese women with primary osteoporosis

Suzuki T, Nakamura Y, Kato H

OBJECTIVES: The aim of this study was to examine the efficacy, safety, and adherence of ibandronate (IBN) treatment with or without vitamin D supplementation for 3 years in Japanese women...
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Compliance and discontinuation of denosumab treatment in postmenopausal Japanese women with primary osteoporosis or rheumatoid arthritis and osteoporosis

Suzuki T, Nakamura Y, Kamimura M, Ikegami S, Uchiyama S, Kato H

OBJECTIVES: The aim of this study was to examine the discontinuation and occurrence of fracture during denosumab treatment in Japanese women with primary osteoporosis or rheumatoid arthritis (RA) with osteoporosis. METHODS:...
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Efficacy and safety of adding mizoribine to standard treatment in patients with immunoglobulin A nephropathy: A randomized controlled trial

Hirai K, Ookawara S, Kitano T, Miyazawa H, Ito K, Ueda Y, Kaku Y, Hoshino T, Mori H, Yoshida I, Kubota K, Yamaji Y, Takeda T, Nakamura Y, Tabei K, Morishita

BACKGROUND: Mizoribine (MZR) is an immunosuppressive drug used in Japan for treating patients with lupus nephritis and nephrotic syndrome and has been also reportedly effective in patients with immunoglobulin A...
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Comparison of effectiveness and safety of ibandronate and minodronate combined with eldecalcitol in primary osteoporosis of women: A 1-year follow-up study

Tanaka M, Nakamura Y, Itoh S, Kato Y

OBJECTIVES: This is an open labeled and retrospective cohort study which compared the effectiveness and safety of ibandronate (IBN) and minodronate (MIN) combined with eldecalcitol (ELD) in primary osteoporosis of...
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Monthly minodronate inhibits bone resorption to a greater extent than does monthly risedronate

Kamimura M, Nakamura Y, Ikegami S, Komatsu M, Uchiyama S, Kato H

As a bisphosphonate, minodronate (MIN) is one of the strongest inhibitors of bone resorption. However, there have been no reports directly comparing the antiresorptive effects of monthly MIN with those...
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Ampullary Adenoma Treated by Endoscopic Double-Snare Retracting Papillectomy

Soma H, Miyata N, Hozawa S, Higuchi H, Yamagishi , Nakamura Y, Saeki K, Kameyama K, Masugi Y, Yahagi N, Kanai T

We report herein improved methods for the safe and successful completion of endoscopic papillectomy (EP). Between January 2008 and November 2011, 12 patients underwent double-snare retracting papillectomy for the treatment...
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Management of open bite that developed during treatment for internal derangement and osteoarthritis of the temporomandibular joint

Arai C, Choi JW, Nakaoka K, Hamada Y, Nakamura Y

This case report describes the orthodontic treatment performed for open bite caused by internal derangement (ID) and osteoarthritis (OA) of the temporomandibular joint (TMJ). A Japanese woman, aged 31 years...
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Curved Periacetabular Osteotomy for the Treatment of Dysplastic Hips

Naito M, Nakamura Y

Curved periacetabular osteotomy (CPO) was developed for the treatment of dysplastic hips in 1995. In CPO, the exposure of osteotomy sites and osteotomy of the ischium are made in the...
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Feasibility of Newly Developed Endoscopic Ultrasound with Zone Sonography Technology for Diagnosis of Pancreatic Diseases

Hirooka Y, Itoh A, Kawashima , Ohno E, Itoh Y, Nakamura Y, Hiramatsu , Sugimoto H, Sumi H, Hayashi D, Ohmiya N, Miyahara R, Nakamura M, Funasaka K, Ishigami M, Katano Y, Goto H

  • KMID: 1806650
  • Gut Liver.
  • 2013 Jul;7(4):486-491.
BACKGROUND/AIMS: To confirm the feasibility of using newly developed endoscopic ultrasound (EUS) with Zone sonography(TM) technology (ZST; Fujifilm Corp.). METHODS: Seventy-five patients with pancreatic disorders were enrolled: 45 with intraductal papillary...
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Minimally Invasive Surgery for Osteoid Osteoma of the Cervical Spine Using Microendoscopic Discectomy System

Nakamura Y, Yabuki S, Kikuchi SI, Konno SI

We report herein the case of an 18-year-old man who underwent endoscopic resection for an osteoid osteoma in the seventh cervical facet joint. The patient had experienced right neck pain...
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Psychological, Social, and Environmental Factors Associated With Utilization of Senior Centers Among Older Adults in Korea

Kim HS, Miyashita , Harada K, Park JH, So JM, Nakamura Y

OBJECTIVES: The purpose of the study was to examine the relationships among the psychological, social, and environmental factors influencing the utilization of senior centers among older adults in Korea. METHODS: A...
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Use of Senior Center and the Health-Related Quality of Life in Korean Older Adults

Kim HS, Harada K, Miyashita , Lee EA, Park JK, Nakamura Y

OBJECTIVE: The purpose of the present study was to examine the relationship between the use of senior center and health-related quality of life in Korean older adults. METHODS: A questionnaire survey...
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Postoperative Meningitis in Patients with Cervical Cord Tumor: A Case Report

Kawaguchi , Seki S, Yasuda T, Nakamura Y, Nakano M, Kimura T

Postoperative meningitis after spinal surgery is a rare complication that can result in a life-threatening condition. Linezolid (LZD) is an oxazolidinone which has been approved in Japan for infections caused...
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