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A Novel Splice Variant (c.438T>A) of APC, Suspected by Family History and Confirmed by RNA Sequencing

Lee H, Kim HK, Yang DH, Hong YS, Lee W, Lim SB, Byeon JS, Chun S, Min WK

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Clinical Characteristics and Postoperative Outcomes of Patients Presenting With Upper Gastrointestinal Tract Crohn Disease

Moon JS, Lee JL, Yu CS, Lim SB, Park IJ, Yoon YS, Kim CW, Yang SK, Ye BD, Park SH, Alsaleem HA, Kim JC

Purpose: Upper gastrointestinal (GI) tract involvement in Crohn disease (CD) is rare and effectiveness of surgical treatment is limited. The aim of this study was to evaluate characteristics and surgical...
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Identification of a Novel Splice Variant (c.423-8A>G) of APC by RNA Sequencing

Kim A, Kim HK, Ahn S, Hong YS, Lim SB, Byeon JS, Chun S, Min WK, Lee W

No abstract available.
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Association of Body Composition with Long-Term Survival inNon-metastatic Rectal Cancer Patients

Han JS, Ryu H, Park IJ, Kim KW, Shin Y, Kim SO, Lim SB, Kim CW, Yoon YS, Lee JL, Yu CS, Kim JC

Purpose We evaluated the association of body composition with long-term oncologic outcomes in non-metastatic rectal cancer patients. Materials and Methods We included 1,384 patients with stage(y)0-III rectal cancer treated at Asan Medical Center between January...
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Management of isolated para-aortic lymph node recurrence after surgery for colorectal cancer

Kim YI, Park IJ, Park JH, Kim TW, Ro JS, Lim SB, Yu CS, Kim JC

PURPOSE: The rare incidence of isolated para-aortic lymph node (PALN) recurrence of colorectal cancer has precluded the formulation of treatment guidelines. This study evaluated and compared the effects of different...
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Short-term Outcomes of Elective 2-Stage Restorative Proctocolectomy for Ulcerative Colitis in Korea: Does Laparoscopy Have Benefits?

Bong JW, Yoon YS, Lee JL, Kim CW, Park IJ, Lim SB, Yu CS, Kim JC

Purpose: This study aimed to compare the short-term outcomes of the open and laparoscopic approaches to 2-stage restorative proctocolectomy (RPC) for Korean patients with ulcerative colitis (UC). Methods: We retrospectively analyzed...
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Long-term Transanal Excision Outcomes in Patients With T1 Rectal Cancer: Comparative Analysis of Radical Resection

Hwang Y, Yoon YS, Bong JW, Choi HY, Song IH, Lee JL, Kim CW, Park IJ, Lim SB, Yu CS, Kim JC

PURPOSE: Transanal excision (TAE) is an alternative surgical procedure for early rectal cancer. This study compared long-term TAE outcomes, in terms of survival and local recurrence (LR), with total mesorectal...
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Prognostic Implications of Extranodal Extension in Relation to Colorectal Cancer Location

Kim CW, Kim J, Park Y, Cho DH, Lee JL, Yoon YS, Park IJ, Lim SB, Yu CS, Kim JC

PURPOSE: Extranodal extension (ENE) is closely associated with the aggressiveness of both colon and rectal cancer. This study evaluated the clinicopathologic significance and prognostic impact of ENE in separate populations...
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Oncologic Outcomes of Organ Preserving Approaches in Patients With Rectal Cancer Treated With Preoperative Chemoradiotherapy

Park IJ, Lee JL, Yoon YS, Kim CW, Lim SB, Yu CS, Kim JC

PURPOSE: We evaluated the oncologic outcomes of organ-preserving strategies in patients with rectal cancer treated with preoperative chemoradiotherapy (PCRT). METHODS: Between January 2008 and January 2013, 74 patients who underwent wait-and-watch...
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Variation in the Height of Rectal Cancers According to the Diagnostic Modalities

Yeom SS, Park IJ, Yang DH, Lee JL, Yoon YS, Kim CW, Lim SB, Park SH, Kim HJ, Yu CS, Kim JC

PURPOSE: Although the height of a rectal tumor above the anal verge (tumor height) partly determines the treatment strategy, no practical standard exists for reporting this. We aimed to demonstrate...
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Does the Different Locations of Colon Cancer Affect the Oncologic Outcome? A Propensity-Score Matched Analysis

Yang KM, Park IJ, Lee JL, Yoon YS, Kim CW, Lim SB, Kim NY, Hong S, Yu CS, Kim JC

PURPOSE: We evaluate the prognostic value of primary tumor location for oncologic outcomes in patients with colon cancer (CC). METHODS: CC patients treated with curative surgery between 2009 and 2012 were...
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Does total regression of primary rectal cancer after preoperative chemoradiotherapy represent “no tumor” status?

Jeong SA, Park IJ, Hong SM, Bong JW, Choi HY, Seo JH, Kim HE, Lim SB, Yu CS, Kim JC

PURPOSE: Insistence that total regression of primary tumor would not represent long-term oncologic outcomes has been raised. Therefore, this study aimed to evaluate the outcomes of these patients after preoperative...
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A Case of Lynch Syndrome with the Deletion of Multiple Exons of the MLH1 Gene, Detected by Next-Generation Sequencing

Hong J, Kim H, Hong YS, Lee W, Lim SB, Byeon JS, Chun S, Min WK

A 26-year-old man underwent colonoscopy to investigate weight loss and a lesion suspicious of colorectal cancer was detected. He had a family history of colorectal cancer and hepatocellular carcinoma. The...
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Factors associated with Experience of Diagnosis and Utilization of Chronic Diseases among Korean Elderly : Focus on Comparing between Urban and Rural Elderly

Lee MJ, Kown DH, Kim YY, Kim JH, Moon SJ, Park KW, Park IW, Park JY, Baek NY, Son GS, Ahn SY, Yeo IU, Woo SA, Yoo SY, Lee GB, Lim SB, Jang SH, Jeong SJ, Jung YJ, Cho SG, Cha JS, Hwang KS, Lee TJ, Lee MS

OBJECTIVES: The purpose of this study was to identify and compare the difference and related factors with general characteristic and health behaviors, a experience of diagnosis and treatment of chronic...
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Hepatic resection after neoadjuvant chemotherapy for patients with liver metastases from colorectal cancer: need for cautious planning

Kim YI, Park IJ, Kim JE, Kim SY, Park JH, Lee JH, Ha TY, Hong YS, Kim SY, Kim TW, Lim SB, Yu CS, Kim JC

PURPOSE: Current neoadjuvant chemotherapy (NAC) may enable therapies such as surgical resection and local ablation of metastases in patients with colorectal liver metastasis (CLM). We evaluated outcomes in CLM patients...
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Sensitivity of Various Evaluating Modalities for Predicting a Pathologic Complete Response After Preoperative Chemoradiation Therapy for Locally Advanced Rectal Cancer

Jung S, Parajuli A, Yu CS, Park SH, Lee JS, Kim AY, Lee JL, Kim CW, Yoon YS, Park IJ, Lim SB, Kim JC

PURPOSE: We investigated the sensitivity of various evaluating modalities in predicting a pathologic complete response (pCR) after preoperative chemoradiation therapy (PCRT) for locally advanced rectal cancer (LARC). METHODS: From a population...
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Primary malignant melanoma of the small intestine: a report of 2 cases and a review of the literature

Yang KM, Kim CW, Kim SW, Lee JL, Yoon YS, Park IJ, Lim SB, Yu CS, Kim JC

The majority of malignant melanomas in the small intestine are metastases from primary cutaneous lesions, it can also develop as a primary mucosal tumor in the gastrointestinal tract. In this...
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Trephine Transverse Colostomy Is Effective for Patients Who Have Previously Undergone Rectal Surgery

Yeom SS, Kim CW, Jung SW, Oh SH, Lee JL, Yoon YS, Park IJ, Lim SB, Yu CS, Kim JC

PURPOSE: Colostomy creation is an essential procedure for colorectal surgeons, but the preferred method of colostomy varies by surgeon. We compared the outcomes of trephine colostomy creation with open those...
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Control of type O foot-and-mouth disease by vaccination in Korea, 2014–2015

Park JH, Tark D, Lee KN, Chun JE, Lee HS, Ko YJ, Kye SJ, Kim YJ, Oem JK, Ryoo S, Lim SB, Lee SY, Choi JH, Ko MK, You SH, Lee MH, Kim B

On December 3, 2014, a type O foot-and-mouth disease (FMD) outbreak began in Korea. Although vaccinations were administered, FMD cases increased steadily for five months, and reached 185 cases by...
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Characterization of Echinostoma cinetorchis endoribonuclease, RNase H

Lim SB, Cha SH, Jegal S, Jun H, Park SH, Jeon BY, Pak JH, Bakh YY, Kim TS, Lee HW

Echinostoma cinetorchis is an oriental intestinal fluke causing significant pathological damage to the small intestine. The aim of this study was to determine a full-length cDNA sequence of E. cinetorchis...
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