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Efficacy of zoledronic acid in older prostate cancer patients undergoing androgen deprivation therapy

Kojima I, Naito Y, Yamamoto A, Terashima , Sho N, Nagayama J, Okada Y, Nagai T

OBJECTIVES: The purpose of this study is to evaluate the efficacy of annual zoledronic acid treatment in Japanese patients with nonmetastatic prostate cancer during androgen deprivation therapy (ADT). METHODS: This is...
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Sweet Taste-Sensing Receptors Expressed in Pancreatic beta-Cells: Sweet Molecules Act as Biased Agonists

Kojima I, Nakagawa Y, Ohtsu Y, Medina A, Nagasawa M

The sweet taste receptors present in the taste buds are heterodimers comprised of T1R2 and T1R3. This receptor is also expressed in pancreatic beta-cells. When the expression of receptor subunits...
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The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic beta-Cells

Kojima I, Nakagawa Y

The sweet taste receptor is expressed in taste cells located in taste buds of the tongue. This receptor senses sweet substances in the oral cavity, activates taste cells, and transmits...
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