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Surgical Management of Comminuted Midshaft Clavicle Fractures Using Reconstruction Plate and Circumferential Wiring: Does the Circumferential Wiring Interfere with the Bone Union?

Kim KT, Shin CS, Park YC, Kim Dh, Kim MW

Purpose: This study examined the radiological and clinical outcomes of internal fixation using a reconstruction plate and 21G circumferential wire in comminuted midshaft clavicular fractures. Materials and Methods: A retrospective cohort...
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Surgical Treatment Outcomes of Acquired Benign Tracheoesophageal Fistula: A Literature Review

Kim SP, Lee J, Lee SK, Kim DH

Background: Tracheoesophageal fistula (TEFs) is a rare condition that requires complex surgical treatment. We analyzed the surgical outcomes of TEF reported in the literature and at Pusan National University Yangsan...
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Treatment of Recurrent Hemarthrosis Following Total Knee Arthroplasty Using Surgical Interventions

Park KH, Kim DH, Jang SW, Ryu JH, Ko KY

Background: Recurrent hemarthrosis following total knee arthroplasty (TKA) is a rare complication. Its pathophysiology and standard treatments have not yet been established. In this study, we report 7 cases of...
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IL-10 Deficiency Aggravates Renal Inflammation, Fibrosis and Functional Failure in High-Fat Dieted Obese Mice

Kim DH, Chun SY, Lee E, Kim B, Yoon B, Gil H, Han MH, Ha YS, Lee JN, Kwon TG, Kim BS, Jang BI

BACKGROUND: High-fat diet-induced obesity is one of the major cause of chronic renal failure. This obesity-related renal failure is mainly caused by inflammatory processes. However, the role of the major...
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Neutrophil-to-Lymphocyte Ratio at Emergency Room Predicts Mechanical Complications of ST-segment Elevation Myocardial Infarction

Yoon GS, Choi SH, Woo SI, Baek YS, Park SD, Shin SH, Kim DH, Kwan J, Lee MJ, Kwon SW

Background: The neutrophil-to-lymphocyte ratio (NLR) has been proven to be a reliable inflammatory marker. A recent study reported that elevated NLR is associated with adverse cardiovascular events in patients with...
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Valsartan Dosage on Ventriculo-Vascular Coupling Index Dose-Dependency in Heart Failure Patients

Ahn KJ, Yu J, Jang AY, Kim DH, Kwan J, Chung WJ

Purpose: Heart failure (HF) poses significant morbidity and mortality. Recently, the ventriculo-vascular coupling index (VVI) was introduced as an independent prognostic factor reflective of the overall cardiovascular performance index in...
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SP-8356, a (1S)-(-)-Verbenone Derivative, Inhibits the Growth and Motility of Liver Cancer Cells by Regulating NF-κB and ERK Signaling

Kim DH, Yong HJ, Mander S, Nguyen HT, Nguyen LP, Park HK, Cha HK, Kim WK, Hwang JI

Liver cancer is a common tumor and currently the second leading cause of cancer-related mortality globally. Liver cancer is highly related to inflammation as more than 90% of liver cancer...
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Efficacy and Tolerability of Solifenacin Fumarate with Overactive Bladder Patients: A Multicenter Observational Study

Shim JH, Choi SY, Gook JH, Kim YJ, Cha WH, Kim DH, Kim KH, Park YW, Um JM, Lim IS, Seo KK, Cho KS, Lee YJ, Lee MK, Kim TH

Purpose: Overactive bladder (OAB) is characterized by a series of highly prevalent symptoms among older adults. This study used the Overactive Bladder Symptom Score (OABSS) and Patient Perception of Bladder...
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Common Mental Disorders in Primary Care

Kim DH

Mental disorders are common in primary care practice. Half of the population experience at least one mental disorder in their lifetime and at least 25% have suffered a mental disorder...
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Coronavirus Disease 2019: Reasons for Better Clinical Course for Children Compared to Adults

Kwak BO, Kim DH

There have been several reports on why the clinical course of coronavirus disease 2019 (COVID-19) in pediatric patients is milder than in adults. There are distinctive points in the immune...
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Clinical, Imaging, and Laboratory Markers of Premanifest Spinocerebellar Ataxia 1, 2, 3, and 6: A Systematic Review

Kim DH, Kim R, Lee JY, Lee KM

Background and Purpose Premanifest mutation carriers with spinocerebellar ataxia (SCA) can exhibit subtle abnormalities before developing ataxia. We summarized the preataxic manifestations of SCA1, -2, -3, and -6, and their...
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Predictive Role of Endoscopic Surveillance after Total Gastrectomy with R0 Resection for Gastric Cancer

Lee JS, Lee JH, Kim J, Na HK, Ahn JY, Jung KW, Kim DH, Choi KD, Song HJ, Lee GH, Jung HY

Background: Endoscopic surveillance after total gastrectomy (TG) for gastric cancer is routinely performed to detect tumor recurrence and postoperative adverse events. However, the reports on the clinical benefits of endoscopic surveillance...
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Changes of Prosapogenin Components in Tienchi Seng (Panax notoginseng) by Ultrasonic Thermal Fusion Process

Lee JB, Yang BW, Kim DH, Jin D, Ko SK

The purpose of this study is to develop a new method of producing tienchi seng (notoginseng, Panax notoginseng) extracts featuring high concentrations of the ginsenoside Rg3, Rg5, and Rg6, special...
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Feasibility of Improving the Accuracy of Dose Calculation Using Hybrid Computed Tomography Images: A Phantom Study

Jeon H, Kim DW, Joo JH, Ki Y, Kim W, Park D, Nam J, Kim DH

Purpose: Kilovoltage computed tomography (kV-CT) is essential for radiation treatment planning. However, kV-CT images are significantly distorted by artifacts when a metallic prosthesis is present in the patient's body. Thus, the...
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Heregulin-β1 Activates NF-E2-related Factor 2 and Induces Manganese Superoxide Dismutase Expression in Human Breast Cancer Cells via Protein Kinase B and Extracellular Signal-regulated Protein Kinase Signaling Pathways

Park JY, Saeidi S, Kim EH, Kim DH, Na HK, Keum JS, Surh YJ

Heregulin-β1, a ligand of ErbB-2 and ErbB-3/4 receptors, has been reported to potentiate oncogenicity and metastatic potential of breast cancer cells. In the present work, treatment of human mammary cancer...
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The Effect of Changes in Family Developmental Stage According to Child Independence on the Incidence of Depression in South Korean Middle-Aged Adults

Lee HJ, Hong SW, Kim DH, Suh YS, Kim JW, Lee NR

Background: The incidence of depression in middle-aged adults is increasing and has been affected by physiological changes and various sociodemographic factors. The present study aimed to examine the longitudinal relationship...
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Characteristics of Elbow Dislocation in Patients with Preexisting Cubitus Varus

Cho CH, Kim DH, Park SG, Shin D, Kim BS

Background: The aim of this study was to investigate the clinical presentations, patterns of soft-tissue injuries, and outcomes of treatment of elbow dislocations in patients with preexisting cubitus varus. Methods: Four...
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Clinical features of internal hernia after gastrectomy for gastric cancer

Ahn Hm, Lee SH, Jeon TY, Kim DH, Choi CI, Kim SJ, Choi CW, Kim TU, Kim KH, Hwang SH

Purpose: Internal hernia after gastrectomy is a rare but potentially life-threatening condition without surgical intervention. Clinical risk factors of internal hernia should, hence, be reviewed after gastrectomy. From 2008 to 2018,...
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Performance Changes Following the Revision of Organ Allocation System of Lung Transplant: Analysis of Korean Network for Organ Sharing Data

Yeo HJ, Kim DH, Kim YS, Jeon D, Cho WH

Background: There is currently a lack of data on the impact of the recent revision of the domestic lung allocation system on transplant performance. Methods: We conducted a retrospective analysis of...
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A Novel Anti-PD-L1 Antibody Exhibits Antitumor Effects on Multiple Myeloma in Murine Models via Antibody-Dependent Cellular Cytotoxicity

Ahn JH, Lee BH, Kim SE, Kwon BE, Jeong H, Choi JR, Kim MJ, Park Y, Kim BS, Kim DH, Ko HJ

Multiple myeloma is a malignant cancer of plasma cells. Despite recent progress with immunomodulatory drugs and proteasome inhibitors, it remains an incurable disease that requires other strategies to overcome its...
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