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Effect of Ursodeoxycholic Acid on the Biodistribution and Excretion of Technetium-99m Radiopharmaceuticals in Rat: A Potential Image Quality Enhancer

Han YH, Jeong HJ, Kim EM, Boud F, Lim ST, Lee SY, Sohn MH

Purpose: This study aimed to investigate the effect of ursodeoxycholic acid (UDCA) on the biodistribution and excretion of technetium-99m (Tc-99m)-labeled radiopharmaceuticals. Materials and Methods: Tc-99m hydroxy-methylene-diphosphonate (HDP), Tc-99m pertechnetate, and Tc-99m...
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Analysis of Circadian Rhythms in the Research of Psychiatric Disorders

Kim SY, Moon E, Jeong HJ

  • KMID: 2513150
  • J Korean Soc Biol Ther Psychiatry.
  • 2021 Feb;27(1):5-11.
In the field of psychiatry, studies on circadian rhythms are increasing. This research trend is based on the emerging evidence on the relationship between circadian rhythm and pathophysiology and prognosis...
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Usefulness of Maximal Expiratory Pressure in Evaluating Dysphagia after Ischemic Stroke

Jang BS, Jeong HJ, Choi HE, Lee JH, Sim YJ, Kim GC

Objective: We investigated the usefulness of maximal expiratory pressure (MEP) in evaluating dysphagia subsequent to ischemic stroke. Methods: This study included patients with ischemic stroke who underwent MEP testing and videofluoroscopic...
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Liposomes: Biomedical Applications

Kim EM, Jeong HJ

Liposomes, with their flexible physicochemical and biophysical properties, continue to be studied as an important potential a critical drug delivery system. Liposomes have overcome the challenges of conventional free drug...
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The effect of general health status, oral health behavior and status on quality of life in Korea adults

Jeong HJ, Kim YH, Yun JW, Oh SH, Yoon HS, Lee MK, Lee JH

Objectives: The purpose of this study was to analyze the relations between general health status, oral health behavior, oral health status, and quality of life, as well as the mediating...
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Anger-Related Characteristics According to Chronotypes in Bipolar or Depressive Disorders

Kang TU, Moon E, Choi Y, Suh H, Park JM, Lee BD, Lee YM, Jeong HJ, Kim SY, Lee K, Lim HJ, Yoon M

Objective Though anger was highly associated with eveningness in general population, there is no study on the relationship between chronotype and anger-related characteristics in bipolar or depressive disorders. This study...
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Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature

Kim M, Chung H, Yang WI, Jeong HJ

Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and dyspnea. On physical and...
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Various Psychiatric Manifestation in DiGeorge Syndrome (22q11.2 Deletion Syndrome): A Case Report

Kim G, Moon E, Park JM, Lee BD, Lee YM, Jeong HJ, Kim SY, Lee K, Suh H

  • KMID: 2505681
  • Clin Psychopharmacol Neurosci.
  • 2020 Aug;18(3):458-462.
  • doi: esmun@hanmail.net
This case report aimed to describe various psychiatric manifestation and treatment course in a patient with DiGeorge syndrome. Psychiatric symptoms and treatment course in a female patient with DiGeorge syndrome...
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Rodent Leukocyte Isolation and Radiolabeling for Inflammation Imaging Study

Kim EM, Oh PS, Boud F, Jeong HJ, Lim ST, Sohn MH

Purpose: The objective of this study was to describe to develop methods of rodent leukocyte isolation and radiolabeling for in vivo inflammation imaging. Methods: Thigh muscle inflammation was induced by injection...
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The Effects of Different Intensity of Aerobic Exercise for Four Weeks on Cardiovascular Risk Factors, Reactive Oxygen, and Antioxidant Enzymes in Old Mice

Kim JH, Jeon S, Jeong HJ, Jeon MY

Purpose: The purpose of this study was to determine the effects of different intensity of aerobic exercise for four weeks on cardiovascular risk factors, reactive oxygen, and antioxidant enzymes in...
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Decreased Hippocampal Metabolism in Amnestic Mild Cognitive Impairment: Positron Emission Tomography Study

Park Ch, Lee YM, Park J, Lee BD, Moon E, Jeong HJ, Kim SY, Lee KY, Suh H, Park HK, Kim HJ, Park K, Mun CW, Chung YI

  • KMID: 2500624
  • J Korean Geriatr Psychiatry.
  • 2020 Apr;24(1):37-41.
Objective: Little is known about factors influencing of hippocampal metabolism (HM) in mild cognitive impairment (MCI). Our objective was to determine whether HM in patients with amnestic MCI (aMCI) is...
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Expression of Phospholipase A2 Receptor in PediatricHepatitis B Virus-Related Membranous Nephropathy

Choi SE, Bae YS, Lee KH, Shin JI, Jeong HJ, Lim BJ

Purpose: Hepatitis B virus (HBV) infection is among etiologies of secondary membranous nephropathy (MN) in pediatric patients. We evaluated expression of phospholipase A2 receptor (PLA2R), a specific target antigen of primary MN, in pediatric...
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Radioactivity Reduction of 2-Deoxy-2-[18F] Fluoro-D-Glucose by Milkand Ursodeoxycholic Acid in Preclinical Study

Jeong HJ, Bagalkot TR, Kim HS, Han YH, Kim M, Lim ST, Sohn MH

Purpose 2-Deoxy-2-[18F] fluoro-d-glucose positron emission tomography (18F-FDG-PET) is a less-invasive and widely used diagnostic tool for detection of malignant tumors. However, prolonged retention of 18F-FDG in the body increases radiation exposure. This...
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[18F]THK5351 PET Imaging in Patients with Mild Cognitive Impairment

Jeong HJ, Lee H, Lee SY, Seo S, Park KH, Lee YB, Shin DJ, Kang JM, Yeon BK, Kang SG, Cho J, Seong JK, Okamura N, Villemagne VL, Na DL, Noh Y

Background and Purpose Mild cognitive impairment (MCI) is a condition with diverse clinical outcomes and subgroups. Here we investigated the topographic distribution of tau in vivo using the positron emission tomography...
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Clinical Significance of Elevated Serum Immunoglobulin G4 Levels in Patients With Rheumatoid Arthritis

Kim SH, Jeong HJ, Kim JM, Jun JB, Son CN

OBJECTIVE: This study aimed to evaluate the relationship between serum immunoglobulin G4 (IgG4) levels and the presence and disease activity of rheumatoid arthritis (RA). METHODS: The study enrolled 128 participants (RA,...
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Diagnosis of renal transplant rejection: Banff classification and beyond

Jeong HJ

Diagnosis of renal transplant rejection is dependent on interpretation of renal allograft biopsies. The Banff Classification of Allograft Pathology, which was developed as a standardized working classification system in 1991,...
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Usefulness of Psoas Muscle Cross-Sectional Area in Evaluating Physical Performance in Patients with Liver Cirrhosis

Jang BS, Choi HE, Lee JH, Sim YJ, Kim GC, Jeong HJ

Objectives: To investigate the relationship between the psoas muscle cross-sectional area and physical performance in patients with liver cirrhosis. Methods: This study analyzed ambulatory patients with liver cirrhosis aged < 65...
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Intranasal Administration of Melanin-Concentrating Hormone Reduces Stress-Induced Anxiety- and Depressive-Like Behaviors in Rodents

Oh JY, Liu QF, Hua C, Jeong HJ, Jang JH, Jeon S, Park HJ

  • KMID: 2510507
  • Exp Neurobiol.
  • 2020 Dec;29(6):453-469.
  • doi: 10.5607/en20024
Major depressive disorder is a complex neuropsychiatric disorder with few treatment options. Non-targeted antidepressants have low efficacy and can induce series of side effects. While a neuropeptide, melanin-concentrating hormone (MCH),...
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Engineering Human Brain Organoids: From Basic Research to Tissue Regeneration

Jeong HJ, Jimenez Z, Mukhambetiyar K, Seo M, Choi JW, Park TE

BACKGROUND: Brain organoids are self-organized from human pluripotent stem cells and developed into various brain region following the developmental process of brain. Brain organoids provide promising approach for studying brain...
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Three-dimensional evaluation of the correlation between lip canting and craniofacial planes.

Jeong HJ

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