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Relationships between lung function and clinical findings in school-age survivors of preterm birth

Kim YH, Jeong JE, Chung HL, Jang YY

Purpose: Survivors of preterm birth are at high risk of chronic pulmonary disease. We examined lung function in the school-age children born preterm and investigated the relationship between lung function...
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SYM 2081 Exerts Neuroprotective Effect Modulating Anti-Apoptosis in the Hypoxic-Ischemic Brain Injury of Neonatal Rats

Park JK, Jang YY, Jeong JE, Lee EJ, Choi EJ, Chung HL, Kim WT

OBJECTIVE: SYM 2081 ((2S,4R)-4-methylglutamic acid), an agonist and functional antagonist of the kainite receptor, has shown a neuroprotective effect in neurodegenerative diseases in adults but little is known concerning perinatal...
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A novel compound heterozygous mutation in DNAH5 in a Korean neonate with primary ciliary dyskinesia

Lee NW, Jeong JE, Jang YY, Chung HL

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disease affecting motile cilia. A female neonate was hospitalized with respiratory distress 72 hours after birth and showed concurrent situs inversus. She...
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A case of vitamin D hydroxylation-deficient rickets type 1A caused by 2 novel pathogenic variants in CYP27B1 gene

Kim YM, Jang YY, Jeong JE, Park HJ, Jang JH, Kim JK

Vitamin D hydroxylation-deficient rickets type 1A (VDDR1A, OMIM 264700) is a rare autosomal recessive inherited disorder. Pathogenic variants in the CYP27B1 gene lead to loss of 1α-hydroxylase activity. We report...
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Seasonal patterns and etiologies of croup in children during the period 2010–2015: A multicenter retrospective study

Lee YJ, Kim HB, Kim BS, Kim CK, Kim CH, Kim HY, Kim S, Kim Y, Park C, Seo JH, Sol IS, Sung M, Song MS, Song DJ, Ahn YM, Oh HL, Yu J, Lee KS, Lee E, Lee JS, Jang GC, Jang YY, Chung EH, Chung HL, Choi SM, Choi YJ, Han MY, Yang HJ, Shim JY, Kim JT, The Pneumonia & Respiratory Disease Study Group of Korean Academy of Pediatric Allergy and Respiratory Disease

PURPOSE: Croup is known to have epidemics in seasonal and biennial trends, and to be strongly associated with epidemics of parainfluenza virus. However, seasonal and annual epidemics of croup have...
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Neuroprotective Effects of SYM 2081, Targeting Kainate Receptors in the Neonatal Hypoxic-Ischemic Brain Injury

Lee JH, Lee EJ, Jang YY, Jeong JE, Chung HL, Kim WT

PURPOSE: Glutamate induced excitotoxicity has been implicated as a major factor of central neuronal death in neonatal hypoxic-ischemic (HI) injury. Kainate receptors (KARs) are one of glutamatergic receptors involving glutamate...
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Significance of total serum IgE in children with lower respiratory infections due to respiratory syncytial virus

Jang YY, Lee HS, Jeong JE, Hong SJ, Park HJ, Lee KH, Kim W, Chung HL

PURPOSE: Respiratory syncytial virus (RSV) is known to induce Th2 immune response with increased IgE production. We investigated serum IgE levels in RSV bronchiolitis/pneumonia (RSV-LRI) in relation to disease severity. METHODS:...
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Clinical significance of increased vascular endothelial growth factor, transforming growth factor-beta1, and YKL-40 in the serum of children with asthma

Jang YY, Lee HS, Jeong JE, Lee EJ, Hong SJ, Park HJ, Lee KH, Kim W, Chung HL

PURPOSE: Vascular endothelial growth factor (VEGF), transforming growth factor beta1 (TGF-beta1), and platelet derived growth factor (PDGF) are known to be involved in the pathogenesis of inflammation and remodeling in...
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Ex vivo Expansion of Human Natural Killer Cells from Blood Retained in a Disposable Platelet Apheresis Set

Shin DJ, Cho D, Jang YY, Park JY, Kim JS, Kim SK, Lee JJ, Jang MJ, Shin MG, Ryang DW

  • KMID: 1440719
  • Korean J Blood Transfus.
  • 2012 Apr;23(1):28-37.
BACKGROUND: Natural killer cells expanded from human peripheral blood (PB) have been used in cancer immunotherapy research. Although most research teams have access to human PB, it is necessary to...
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Transient asymptomatic white matter lesions following Epstein-Barr virus encephalitis

Jang YY, Lee KH

We present the case of a patient with Epstein-Barr virus (EBV) encephalitis who developed abnormal white matter lesions during the chronic phases of the infection. A 2-year-old-boy was admitted for...
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Myofascial Pain Syndrome in Patients with Cervical Vertigo

Cho DK, Rhee CK, Lee SJ, Jang YY, Hyun JK

  • KMID: 2327339
  • J Korean Acad Rehabil Med.
  • 2011 Apr;35(2):243-249.
OBJECTIVE: To delineate the clinical manifestation of myofascial pain syndrome (MPS) around the face, neck and shoulders in patients with cervical vertigo (CV) and to determine whether treatment of MPS...
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Alpha-Type 1 Polarized Dendritic Cells Loaded with Apoptotic Allogeneic Breast Cancer Cells Can Induce Potent Cytotoxic T Lymphocytes against Breast Cancer

Park MH, Yang DH, Kim MH, Jang JH, Jang YY, Lee YK, Jin CJ, Pham TN, Thi TA, Lim MS, Lee HJ, Hong CY, Yoon JH, Lee JJ

  • KMID: 1804676
  • Cancer Res Treat.
  • 2011 Mar;43(1):56-66.
PURPOSE: Various tumor antigens can be loaded onto dendritic cells (DCs) to induce a potent cytotoxic T lymphocyte (CTL) response in DC-based immunotherapy against breast cancer. However, in the clinical...
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Collet-Sicard Syndrome in a Patient with Jefferson Fracture

Kwon HC, Cho DK, Jang YY, Lee SJ, Hyun JK, Kim TU

Collet-Sicard syndrome is a rare condition characterized by the unilateral paralysis of the 9th through 12th cranial nerves. We describe a case of a 46-year-old man who presented with dysphagia...
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Transient splenial lesion of the corpus callosum in a case of benign convulsion associated with rotaviral gastroenteritis

Jang YY, Lee KH

Transient magnetic resonance (MR) signal changes in the splenium of the corpus callosum (SCC) arise from many different conditions, including encephalopathy or encephalitis caused by infection, seizures, metabolic derangements, and...
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Retinal Protective Effects of Minocycline via Anti-apoptosis on Oxygen-induced Retinopathy in Neonatal Rats

Jang YY, Suh ES, Kim WT

  • KMID: 2072248
  • Korean J Perinatol.
  • 2010 Mar;21(1):26-39.
PURPOSE: Retinopathy of prematurity (ROP) is a leading cause of blindness with retinal detachment due to oxygen toxicity in preterm infants. Recently advances in neonatal care had to led improved...
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The Effect of Tribbles-Related Protein 3 on ER Stress-Suppressed Insulin Gene Expression in INS-1 Cells

Jang YY, Kim NK, Kim MK, Lee HY, Kim SJ, Kim HS, Seo HY, Lee IK, Park KG

BACKGROUND: The highly developed endoplasmic reticulum (ER) structure in pancreatic beta cells is heavily involved in insulin biosynthesis. Thus, any perturbation in ER function inevitably impacts insulin biosynthesis. Recent studies...
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Neuroprotective Effects of Taurine Via Modulation of Nitric Oxide Synthase on Hypoxic-Ischemic Brain Injury in Neonatal Rats

Song EJ, Jang YY, Kim TY, Cha SH, Park HJ, Lee KH, Lee KH, Choi EJ, Kim JK, Chung HL, Seo ES, Kim WT

  • KMID: 1472006
  • Korean J Perinatol.
  • 2009 Sep;20(3):213-224.
PURPOSE: Taurine is a simple sulfur-containing amino acid and enriched in brain, retina, heart and skeletal muscles. In the central nervous system, taurine has been implicated in major phenomena. Current...
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A Case with Partial Monosomy 6q and Partial Trisomy 14q Derived from Maternal Balanced Translocation

Song EJ, Jang YY, Park HJ, Lee KH, Lee KH, Choi EJ, Kim JK, Chung HL, Seo ES, Kim WT

  • KMID: 1980173
  • Korean J Perinatol.
  • 2009 Jun;20(2):163-166.
There are several cases of partial monosomy or partial trisomy derived from maternal balanced translocation, but partial monosomy 6q and partial trisomy 14q derived from maternal balanced translocation has not...
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A case of persistent pulmonary hypertension of the newborn: Treatment with inhaled iloprost

Jang YY, Park HJ

We report a case of a full-term neonate with persistent pulmonary hypertension who developed asphyxia after birth and was treated with iloprost. The neonate had persistent hypoxia and did not...
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Serum Zinc Levels in Young Children with Recurrent Wheeze

Kwon SM, Jang YY, Kim JY, Park HJ, Kim WT, Kim JK, Choi EJ, Lee KH, Chung HL

  • KMID: 2314891
  • Pediatr Allergy Respir Dis.
  • 2008 Sep;18(3):253-259.
PURPOSE: Zinc is a dietary antioxidant which is crucial for normal development and function of the immune system. Zinc supplementation is reported to reduce respiratory infections and prevent severe pneumonia...
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