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Clinical and Virologic Effectiveness of Remdesivir Treatment for Severe Coronavirus Disease 2019 (COVID-19) in Korea: a Nationwide Multicenter Retrospective Cohort Study

Joo EJ, Ko JH, Kim SE, Kang SJ, Baek JH, Heo EY, Shi HJ, Eom JS, Choe PG, Bae S, Ra SH, Kim DY, Kim BN, Kang YM, Kim JY, Chung JW, Chang HH, Bae S, Cheon S, Park Y, Choi H, Lee E, Lee By, Park JW, Sohn Y, Heo JY, Kim SH, Peck KR

Background: Remdesivir is widely used for the treatment of coronavirus disease 2019 (COVID-19), but controversies regarding its efficacy still remain. Methods: A retrospective cohort study was conducted to evaluate the effect...
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The Impact of Erosive Reflux Esophagitis on the Decline of Lung Function in the General Population

Kang HR, Lee YJ, Lee HY, Park TY, Lee JK, Heo EY, Chung HS, Choi SH, Kim DK

Background: The impact of reflux esophagitis on the decline of lung function has been rarely reported. This study was performed to evaluate the association between erosive reflux esophagitis and lung...
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Clinical implication and risk factor of pneumonia development in mild coronavirus disease 2019 patients

Lee HW, Yoon SY, Lee JK, Park TY, Kim DK, Chung HS, Heo EY

Background/Aims Although a majority of coronavirus disease 2019 (COVID-19) cases were characterized as mild, data assessing the development of pneumonia in mild COVID-19 patients are limited. We aimed to examine the...
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Clinical Characteristics of COVID-19: Clinical Dynamics of Mild Severe Acute Respiratory Syndrome Coronavirus 2 Infection Detected by Early Active Surveillance

Suh HJ, Kim DH, Heo EY, Lee HW, Lee JK, Lee CS, Kim M, Jeon YD, Chung JW, Kim YK, Shin PJ, Lee MS, Kang JS, Lee MJ, Kim BN, Park SW

Background: There is limited information describing the presenting characteristics and dynamic clinical changes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosed in the early phase of illness. This...
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Thromboembolism in Mycobacterium tuberculosis Infection: Analysis and Literature Review

Ha H, Kim KH, Park JH, Lee JK, Heo EY, Kim JS, Kim DK, Choi IS, Chung HS, Lim HJ

BACKGROUND: Tuberculosis is associated with hypercoagulation; however, there are few reports of cases thromboembolism and tuberculosis at the same time in the real world. The purpose of this study was...
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The effect of metformin on culture conversion in tuberculosis patients with diabetes mellitus

Lee YJ, Han SK, Park JH, Lee JK, Kim DK, Chung HS, Heo EY

BACKGROUND/AIMS: Patients with diabetes mellitus (DM) and tuberculosis (TB) have increased morbidity and a high risk of treatment failure or recurrence. It is important to manage both diseases simultaneously. Among...
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Guideline for Antibiotic Use in Adults with Community-acquired Pneumonia

Lee MS, Oh JY, Kang CI, Kim ES, Park S, Rhee CK, Jung JY, Jo KW, Heo EY, Park DA, Suh GY, Kiem S

Community-acquired pneumonia is common and important infectious disease in adults. This work represents an update to 2009 treatment guideline for community-acquired pneumonia in Korea. The present clinical practice guideline provides...
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Prediction of Anthracofibrosis Based on Clinico-Radiographic Findings

Park TY, Heo EY, Chung HS, Jin KN, Kim DK

PURPOSE: Because anthracofibrosis (AF) is associated with tuberculosis (TB), detection of AF is clinically relevant in Korea, a TB endemic region. We thus sought to develop and validate a predictive...
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Technology and Policy Challenges in the Adoption and Operation of Health Information Exchange Systems

Ji H, Yoo S, Heo EY, Hwang H, Kim JW

OBJECTIVES: This study aimed to identify problems and issues that arise with the implementation of online health information exchange (HIE) systems in a medical environment and to identify solutions to...
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Effect of Antibiotic Prophylaxis on Early-Onset Pneumonia in Cardiac Arrest Patients Treated with Therapeutic Hypothermia

Kim SJ, Lee JK, Kim DK, Shin JH, Hong KJ, Heo EY

BACKGROUND: Infectious complications frequently occur after cardiac arrest and may be even more frequent after therapeutic hypothermia. Pneumonia is the most common infectious complication associated with therapeutic hypothermia, and it...
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Clinical Effects of Gemifloxacin on the Delay of Tuberculosis Treatment

Kim SY, Yim JJ, Park JS, Park SS, Heo EY, Lee CH, Chung HS, Kim DK

Although gemifloxacin has low in vitro activity against Mycobacterium tuberculosis, the effect of gemifloxacin on the delay of tuberculosis (TB) treatment has not been validated in a clinical setting. The...
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Colon atresia, a rare comorbid condition in VACTERL association

Hwangbo JH, Heo EY, Choo YS, Bae JY, Kim MJ, Seong WJ

Vertebral, anal, cardiac, tracheoesophageal, renal and limb (VACTERL) association is defined by the presence of at least three of the following six congenital malformations: vertebral defects, anal atresia, cardiac defects,...
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Comparing the Certification Criteria for CCHIT-Certified Ambulatory EHR with the SNUBH's EHR Functionalities

Heo EY, Hwang H, Kim EH, Cho EY, Lee KH, Kim TH, Kim KD, Baek RM, Yoo S

OBJECTIVES: This study aims to investigate the suitability of electronic health record (EHR) systems in Korea for global certification and to propose functions for future global systems by comparing and...
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Successful Management of Tracheobronchomalacia Associated with Empyema Using a Covered Metallic Tracheobronchial Stent: A Case Report

Park YS, Kang HJ, Jeong YJ, Choi SM, Heo EY, Moon HJ, Lee CH, Chung HS, Kim DK

Tracheobronchomalacia is developed by excessively weakened walls of the trachea and bronchi, and shows dynamic collapse of the airway on expiration and causes dyspnea. Airway stenting or surgical correction of...
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Massive ascites after cesarean section in a patient with liver cirrhosis

Heo EY, Hwangbo JH, Lee YH, Kim MJ, Bae JY, Seong WJ

Pregnancy is a rare event in patients with cirrhosis. But recently, improvements in the treatment of chronic liver disease have resulted in higher conception rates and more successful pregnancy outcomes....
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Fatal Broncho-Mediastinal Fistula in a Patient with Non-Small Cell Lung Cancer after Photodynamic Therapy

Heo EY, Kim YJ, Yang SC

Photodynamic therapy (PDT) can be used as palliative therapy to reduce obstructive symptoms in patients with advanced lung cancer. Herein, we report on the case of a patient with fatal...
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Sustained fetal sinus bradycardia after maternal cardioversion

Hwangbo JH, Bae JY, Heo EY, Kim MJ, Seong WJ

Direct current cardioversion is reported as a safe procedure during pregnancy. However, the impact of cardioversion on fetal haemodynamics remains unclear. A 28-year-old woman at 10 2/7 weeks of gestation...
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Streptococcus salivarius pneumonia with pulmonary nocardiosis in a rheumatoid arthritis patient treated with immunosuppressants

Jeong I, Heo EY, Lee JS, Kim HR, Lee EY, Kim YW, Yang SC

  • KMID: 2305815
  • Korean J Med.
  • 2009 Jul;77(1):128-132.
Streptococcus salivarius is a Gram-positive organism that belongs to the viridians group of streptococci. It is a relatively non-virulent bacterium that is part of the normal flora. It is rarely...
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Consolidative Bronchioloalveolar Carcinoma Presenting as Pneumonia, and This Led to a Late Diagnosis due to the Improvement after Antibiotic Therapy

Jeong I, Heo EY, Lee JS, Yoon HI, Lee JH, Lee CT, Kang YA

  • KMID: 2319056
  • Tuberc Respir Dis.
  • 2008 Aug;65(2):147-151.
Non-resolving or slowly resolving pulmonary infiltrates in spite of administering adequate antimicrobial therapy are a clinical diagnostic challenge for physicians. The rate of radiographic resolution varies with the patients' age,...
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A Unique Case of Transient Midventricular Ballooning: An Atypical Manifestation of Stress-Induced Cardiomyopathy Involving Both Ventricles

Park HE, Kim JH, Yoon YE, Park JB, Lee W, Cho Y, Heo EY, Kim HK, Kim YJ, Sohn DW

Stress-induced cardiomyopathy is characterized by reversible systolic dysfunction of the ventricles, usually involving the apical segments. It occurs more commonly in women and is frequently precipitated by emotional or physical...
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