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Re-defining T-Cell Exhaustion: Subset, Function, and Regulation

Im SJ, Ha SJ

Acute viral infection or vaccination generates highly functional memory CD8 T cells following the Ag resolution. In contrast, persistent antigenic stimulation in chronic viral infection and cancer leads to a...
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Fibrous Band between Extraocular Muscles in Unilateral Coronal Synostosis

Chung SA, Ha SJ

No abstract available.
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Immediate and Evolutionary Recovery of Left Ventricular Diastolic Function after Transcatheter Aortic Valve Replacement: Comparison with Surgery

Ha SJ, Yoo SY, Hong MK, Hong GR

PURPOSE: We aimed to compare the effect of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (sAVR) on recovery of left ventricular (LV) diastolic function and afterload through...
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Extrinsic Acquisition of CD80 by Antigen-Specific CD8⁺ T Cells Regulates Their Recall Immune Responses to Acute Viral Infection

Son J, Ha SJ

CD80 is mainly expressed on Ag-presenting cells (APCs) as a costimulatory molecule but is also detected on T cells. However, the origin and physiological role of CD80 on CD8⁺ T...
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Analysis of the Health Expenditure and Medical Usage Difference of the Baby Boomers between Male and Female: Depression as a Mediators

Jeong JY, Jeong JY, Cha SJ, Lee HJ

BACKGROUND: This study purposed to compare the difference on medical utilization and health expenditure of baby boomer generation by depression between gender. METHODS: Korea Welfare Panel Survey 2016, provided by the...
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Optic Neuritis Accompanied by Optic Perineuritis after Peribulbar Retinalamin Injection

Lee GM, Ha SJ

PURPOSE: To report a case of optic neuritis accompanied by optic perineuritis after retinalamin peribulbar injection. CASE SUMMARY: A 46-year-old Kazakhstan woman presented with sudden vision loss, headache, and pain in...
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Metabolic Reprogramming by the Excessive AMPK Activation Exacerbates Antigen-Specific Memory CD8⁺ T Cell Differentiation after Acute Lymphocytic Choriomeningitis Virus Infection

Son J, Cho YW, Woo YJ, Baek YA, Kim EJ, Cho Y, Kim JY, Kim BS, Song JJ, Ha SJ

During virus infection, T cells must be adapted to activation and lineage differentiation states via metabolic reprogramming. Whereas effector CD8⁺ T cells preferentially use glycolysis for their rapid proliferation, memory...
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Visual Field Changes after Internal Limiting Membrane Peeling in Glaucoma Patients with Epiretinal Membrane

Park HS, Ha SJ, Ahn JH

PURPOSE: To report visual field changes after internal limiting membrane (ILM) peeling for macular epiretinal membrane (ERM) according to the severity of glaucoma. METHODS: A retrospective review of 37 eyes from...
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Orbital Rim Uptake on Bone Scans and Its Clinical Significance

Hwang YU, Cha SJ

PURPOSE: This study is to evaluate orbital rim uptake on bone scan and to discuss their clinical significance. MATERIALS AND METHODS: From January 2011 to August 2013, 3149 cases of bone...
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Rebound Tonometers versus Other Tonometers: Agreement among Readings and the Effects of Axial Length, Ocular Pulse Amplitude, and Central Corneal Thickness on Readings

Ha SJ

OBJECTIVE: The aim of this study was to use intraocular pressure (IOP) measurements obtained via rebound tonometry (RBT, the I-care instrument), Goldmann applanation tonometry (GAT), non-contact tonometry (NCT), dynamic contour...
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Ergonovine Stress Echocardiography for the Diagnosis of Vasospastic Angina and Its Prognostic Implications in 3,094 Consecutive Patients

Song YJ, Ha SJ, Lee DS, Bang WD, Shin DG, Woo Y, Cheong S, Yoo SY

BACKGROUND AND OBJECTIVES: Ergonovine stress echocardiography (ErgECHO) has been proposed as a noninvasive tool for the diagnosis of coronary vasospasm. However, concern over the safety of ErgECHO remains. This study...
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Content Analysis on University Students who Witnessed School Violence during Their Formative Years

Kim MY, Ha SJ, Kim JH

PURPOSE: The purpose of this study is to explore the experience of university students who witnessed of school violence during their formative years. METHODS: The participants in this study included 30...
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Left ventricular thrombi after simultaneous thrombotic occlusions of multiple coronary arteries presenting acute myocardial infarction: need anticoagulant?

Kim HJ, Choe KJ, Bang WD, Ha SJ, Yoo SY, Cheong S

No abstract available.
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Comparison of Image Quality between Mammography Dedicated Monitor and UHD 4K Monitor, Using Standard Mammographic Phantom: A Preliminary Study

Lee JY, Cha SJ, Hong SH, Kim SY, Kim YH, Kim YS, Kim JA

PURPOSE: Using standard mammographic phantom images, we compared the image quality obtained between a mammography dedicated 5 megapixel monitor (5M) and a UHD 4K (4K) monitor with digital imaging and...
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Semi-Functional Quantitative Flow Cytometry Assay for Lymphocytic Choriomeningitis Virus Titration

Ban YH, Ha SJ

Quantitative PCR and plaque assay are powerful virological techniques used to measure the load of defective or infectious virus in mouse and human. However, these methods display limitations such as...
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Cerebrospinal Fluid Pressure and Trans-lamina Cribrosa Pressure Difference in Open-angle Glaucoma: KNHANES V

Kim YK, Tumurbaatar U, Ohn YH, Ha SJ, Park KH

PURPOSE: To investigate the relationships between estimated cerebrospinal fluid pressure (CSFP) and trans-lamina cribrosa pressure difference (TLCPD) in open-angle glaucoma (OAG) in Korean population. METHODS: A total of 10,801 eyes were...
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Hybrid telescopic double crown denture on maxillary few remaining teeth and 2 mandibular implants in case of failed implant overdenture

Ha SJ, Cho JH

Double crown prostheses can be used in patients who have a few remaining teeth and poor periodontal condition because of secondary splinting of abutments, vertical loading, decrease of the length...
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Altered Biological Potential and Radioresponse of Murine Tumors in Different Microenvironments

Lee IJ, Lee EJ, Park H, Kim W, Ha SJ, Shin YK, Seong J

PURPOSE: This study was conducted to evaluate the biological features of murine hepatocarcinoma according to different tumor microenvironmental models and to determine the change in molecular and immunologic responses after...
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Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues

Park HJ, Lee A, Lee JI, Park SH, Ha SJ, Jung KC

Unlike conventional T cells, innate CD8 T cells develop a memory-like phenotype in the thymus and immediately respond upon antigen stimulation, similar to memory T cells. The development of innate...
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Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications

Yoo S, Ha SJ

Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that bridge innate and adaptive immune responses, thereby leading to immune activation. DCs have been known to recognize pathogen-associated molecular patterns such...
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