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C1qa deficiency in mice increases susceptibility to mouse hepatitis virus A59 infection

Kim HW, Seo SM, Kim JY, Lee JH, Lee HW, Choi YK

Background: Mouse hepatitis virus (MHV) A59 is a highly infectious pathogen and starts in the respiratory tract and progresses to systemic infection in laboratory mice. The complement system is an...
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Treatment of a tooth with furcation involvement and extensive alveolar bone resorption due to endodontic-periodontal combined lesion using root resection: a case report

Choi YK, Kim SY, Jeon HM, Jung KH, Choi NR, Joo JY, Kim HJ, Kwon EY

Due to the complex anatomical structure of the molar, endodontic-periodontal combined lesions often occur, resulting in furcation involvement and extensive alveolar bone resorption. When endodontic-periodontal combined lesions occur through the...
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Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells

Choi YK, Kang JI, Hyun JW, Koh YS, Kang JH, Hyun CG, Yoon KS, Lee KS, Lee CM, Kim TY, Yoo ES, Kang HK

Alopecia is a distressing condition caused by the dysregulation of anagen, catagen, and telogen in the hair cycle. Dermal papilla cells (DPCs) regulate the hair cycle and play important roles...
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Blossom smart expander technology for tissue expander-based breast reconstruction facilitates shorter duration to full expansion: A pilot study

Choi YK, Rochlin DH, Nguyen DH

Background This study evaluated the Blossom system, an innovative self-filling, rate-controlled, pressure-responsive saline tissue expander (TE) system. We investigated the feasibility of utilizing this technology to facilitate implant-based and combined...
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Positivity of Carbapenemase-producing Enterobacteriaceae in Patients Following Exposure within Long-term Care Facilities in Seoul, Korea

Park JJ, Seo YB, Lee J, Eom JS, Song W, Choi YK, Kim SR, Son HJ, Cho NH

Background: Carbapenemase-producing Enterobacteriaceae (CPE) are emerging as a worldwide threat. Long-term care facilities (LTCFs) are considered a reservoir for CPE and play a central role in transmission to acute care...
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Oral health status of Korean adults with implants according to their use of oral hygiene products: results from a nationwide population-based study (2013–2015)

Choi YK, Kim EJ

Purpose: Many home care treatments can be used to promote the health and longevity of dental implants; however, few studies are available to support the concept that selfperformed oral hygiene...
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Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/ β-Catenin Pathway in Dermal Papilla Cells

Kang JI, Choi YK, Koh YS, Hyun JW, Kang JH, Lee KS, Lee CM, Yoo ES, Kang HK

The hair cycle (anagen, catagen, and telogen) is regulated by the interaction between mesenchymal cells and epithelial cells in the hair follicles. The proliferation of dermal papilla cells (DPCs), mesenchymal-derived...
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Effect of Korean Version of Psychological First Aid Training Program on Training Disaster Mental Health Service Provider

Park Hi, Choi SW, Choi Yk, Park Sh, You Se, Baik Mj, Kim H, Hyun J, Seok JH

Objectives This study aimed to develop a Korean version of psychological first aid training program (K-PFA) and examine the education effect on trainees. Methods This study enrolled 485 subjects who completed...
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in vivo multiplex gene targeting with Streptococcus pyogens and Campylobacter jejuni Cas9 for pancreatic cancer modeling in wildtype animal

Chang YJ, Bae J, Zhao Y, Lee G, Han J, Lee YH, Koo OJ, Seo S, Choi YK, Yeom SC

Pancreatic ductal adenocarcinoma is a lethal cancer type that is associated with multiple gene mutations in somatic cells. Genetically engineered mouse is hardly applicable for developing a pancreatic cancer model,...
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Evogliptin, a Dipeptidyl Peptidase-4 Inhibitor, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice

Kim MJ, Kim NY, Jung YA, Lee S, Jung GS, Kim JG, Lee IK, Lee S, Choi YK, Park KG

Renal fibrosis is considered to be the final common outcome of chronic kidney disease. Dipeptidyl peptidase-4 (DPP-4) inhibitors have demonstrated protective effects against diabetic kidney disease. However, the anti-fibrotic effect...
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Temporary replacement of congenital missing incisors on mandible using temporary anchorage devices in growing patient: 2-year follow-up

Choi Yk, Kwon EY, Jung KH, Choi NR, Park SB, Kim Ss, Kim Yi

Agenesis of permanent tooth in adolescent patients can be treated either by orthodontic treatment for space closure or by main-taining the space until implant restoration can be carried out in...
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A multidisciplinary approach to restore crown-root fractured maxillary central incisors: orthodontic extrusion and surgical extrusion

Kwon EY, Kim SY, Jung KH, Choi YK, Kim HJ, Joo JY

To restore a tooth with a fracture line extending below the marginal bone level, a surgical crown lengthening procedure accompanied by ostectomy could be considered to expose the fracture line...
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The Role of a Neurovascular Signaling Pathway Involving Hypoxia-Inducible Factor and Notch in the Function of the Central Nervous System

Kim S, Lee M, Choi YK

In the neurovascular unit, the neuronal and vascular systems communicate with each other. O2 and nutrients, reaching endothelial cells (ECs) through the blood stream, spread into neighboring cells, such as...
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Intrusion of the extruded maxillary central incisor using skeletal anchorage system and unilateral segmental intrusion arch

Kwon EY, Baek YJ, Park SB, Kim SS, Kim YI, Choi YK

Patients who have a moderate periodontitis with pathologic tooth migration of maxillary incisors, it is necessary not only periodontal treatment for reduce periodontal inflammation, but also orthodontic treatment to teeth...
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Differences in Oral Health Status between Rural and Urban Populations of Korean Elders: A Population-Based Study from the Korean National Health and Nutrition Examination Survey VI (2013~2015)

Choi YK, Kim EJ

BACKGROUND: Edentulism is associated with socioeconomic status, rural residence, and chronic disease, but no studies have investigated edentulism and residence factors together. All information that drives a better understanding of...
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Lumbar foraminal neuropathy: an update on non-surgical management

Choi YK

Lumbar foraminal pathology causing entrapment of neurovascular contents and radicular symptoms are commonly associated with foraminal stenosis. Foraminal neuropathy can also be derived from inflammation of the neighboring lateral recess...
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Non-surgical treatment of large periapical lesions

Jung KH, Kwon EY, Kim SY, Jeon HM, Choi YK, Son SA, Park JK

Most periapical lesions can be classified as apical periodontitis, radicular cyst, or abscess. Treatment options for large periapical lesions management range from conventional endodontic treatment to surgical treatment and extraction....
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Comparison of the virulence of Streptococcus pneumoniae in ICR mouse stocks of three different origins

Kim JY, Seo SM, Lee HK, Kim HW, Choi YK

Streptococcus pneumoniae causes many people to suffer from pneumonia, septicemia, and other diseases worldwide. To identify the difference in susceptibility of and treatment efficacy against S. pneumoniae in three ICR...
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Treatment of a tooth with severe periodontal involvement using intentional replantation: case report

Choi YK, Jung KH, Lee JY, Joo JY, Kim HJ, Kwon EY

Although intentional replantation is frequently used as a treatment modality for endodontic problems, severe periodontal involvement has usually been regarded as a contraindication. However, there are some studies suggesting that...
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Guided tissue regeneration therapy after root canal therapy for long standing periodontal-endodontic combined lesion in the mandibular anterior area: case report

Kwon EY, Jung KH, Kim SY, Jeon HM, Choi YK, Joo JY

When inflammatory products are found in both periodontal and pulpal tissues simultaneously, a periodontal-endodontic combined lesion is established. The treatment of periodontal-endodontic combined lesions includes root canal therapy and periodontal...
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