- PIK3CA H1047R Mutation Associated with a Lower Pathological Complete Response Rate in Triple-Negative Breast Cancer Patients Treated with Anthracycline-Taxane–Based Neoadjuvant Chemotherapy
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Guo S, Loibl S, von Minckwitz G, Darb-Esfahani S, Lederer B, Denkert C
- KMID: 2504451
- Cancer Res Treat.
- 2020 Jul;52(3):689-696.
- doi: 10.4143/crt.2019.497
Purpose PIK3CA, encoding for subunit p110a of phosphatidylinositol 3 kinase, is frequently mutated in breast cancer. PIK3CAmutation was predictive for pathological complete response (pCR) in human epidermal growth factor 2 positive... -
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