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Clinical Effect of Hepatitis B Virus on COVID-19 Infected Patients: A Nationwide Population-Based Study Using the Health Insurance Review & Assessment Service Database

Choe JW, Jung YK, Yim HJ, Seo GH

Background: Several studies have recently suggested that liver disease and cirrhosis were risk factors for poor outcomes in patients with coronavirus disease 2019 (COVID-19) infections. However, no large data study has...
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Hepatocellular carcinoma and cancer-related mortality after kidney transplantation with rituximab treatment

Lee H, Kim YH, Lim SJ, Ko Y, Shin S, Jung JH, Baek C, Kim H, Park SK, Kwon H

Purpose: There are increased therapeutic usages of rituximab in kidney transplantation (KT). However, few studies have evaluated the effect of rituximab on cancer development following KT. This study aimed to...
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SARS-CoV-2 Delta Variant Breakthrough Infection and Onward Secondary Transmission in Household

Yi S, Kim JM, Choe YJ, Hong S, Choi S, Ahn SB, Kim M, Park YJ

Background: Despite the extraordinary speed of mass vaccination efforts, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant in a vaccinee with coronavirus disease 2019 (COVID-19) mRNA...
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Meta-Analysis of the Diagnostic Efficacy of the Luminex xTAG Respiratory Viral Panel FAST v2 Assay for Respiratory Viral Infections

Xie LM, Yin X, Xie TA, Su JW, Huang Q, Zhang JH, Huang YF, Guo XG

Purpose: Acute respiratory viral infections pose significant morbidity and mortality, making it essential to diagnose respiratory viral infections rapidly. In this study, the diagnostic efficacy of the Luminex xTAG Respiratory...
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A cost-effectiveness study of universal screening for hepatitis C virus infection in South Korea: A societal perspective

Kim HL, Kim KA, Choi GH, Jang ES, Ki M, Choi HY, Jeong SH

Background/Aims: This study aimed to evaluate the cost-effectiveness of hepatitis C virus (HCV) screening compared to no screening in the Korean population from societal and healthcare system perspectives. Methods: A published...
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Toward a complete cure for chronic hepatitis B: Novel therapeutic targets for hepatitis B virus

Kim SW, Yoon JS, Lee M, Cho Y

Hepatitis B virus (HBV) affects approximately 250 million patients worldwide, resulting in the progression to cirrhosis and hepatocellular carcinoma, which are serious public health problems. Although universal vaccination programs exist,...
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Coronavirus Disease 2019 Vaccines and Pregnancy: Present and Future

Pae J, Ko HS

Coronavirus disease 2019 (COVID-19) from severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection has shown higher morbidity and mortality in pregnant women, compared to non­pregnant women. Until June 2021, among...
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Epstein-Barr Virus-associated Mixed Lymphoepithelioma-like Carcinoma and Adenocarcinoma of the Gall Bladder: An Unusual Entity

Jain N, Goyal S, Sakhuja P, Saluja S

Schmincke described lymphoepithelioma as an undifferentiated carcinoma with abundant lymphoid stroma in the nasopharynx. Tumors with a similar histomorphology in extrapharyngeal areas have been referred to as lymphoepithelioma-like carcinoma (LELC)....
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Isolation, characterization and neutralizing activity of porcine epidemic diarrhea viruses from Vietnam

Do VT, Truong QL, Dao HT, Nguyen TL, Kim J, Hahn TW

Porcine epidemic diarrhea (PED) is characterized by acute enteritis, watery diarrhea, weight loss, dehydration, and death with high mortality in neonatal piglets. In this study, 3 virus isolates collected in...
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Transcriptome Analysis Identifies Altered Biological Processes and Novel Markers in Human Immunodeficiency Virus-1 Long-Term Non-Progressors

Lee D, Yoon CH, Choi SY, Kim JE, Cho YK, Choi BS, Park J

Background: The latent reservoir of Human Immunodificiency Virus-1 (HIV-1) has been a major barrier to the complete eradication of HIV-1 and the development of HIV therapy. Longterm non-progressors (LTNPs) are...
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Safety and Effectiveness of Darunavir in Korean Patients with Human Immunodeficiency Virus 1 Infection: A Post-Marketing Observational Study

Kim H, Kim Y, Kang J

We aimed to evaluate the safety and effectiveness of darunavir (DRV) in the treatment of human immunodeficiency virus-1 (HIV-1) infection in Korea. From October 29, 2010, 225 eligible patients with...
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Prevalence of feline calicivirus and the distribution of serum neutralizing antibody against isolate strains in cats of Hangzhou, China

Zheng M, Li Z, Fu X, Lv Q, Yang Y, Shi F

Background Feline calicivirus (FCV) is a common pathogen of felids, and FCV vaccination is regularly practiced. The genetic variability and antigenic diversity of FCV hinder the effective control and prevention of...
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Waning Effectiveness of One-dose Universal Varicella Vaccination in Korea, 2011–2018: a Propensity Score Matched National Population Cohort

Hong K, Sohn S, Choe YJ, Rhie K, Lee JK, Han MS, Chun BC, Choi EH

Background: Despite high coverage (~98%) of universal varicella vaccination (UVV) in the Republic of Korea since 2005, reduction in the incidence rate of varicella is not obvious. The study aimed to...
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Clinical and Epidemiological Characteristics of Common Human Coronaviruses in Children: A Single Center Study, 2015–2019

Choi YY, Kim C, Choi EH

Purpose: Common human coronaviruses (HCoVs) are relatively understudied due to the mild nature of HCoV infection. Given the lack of local epidemiology data on common HCoVs, we aimed to describe...
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Virus in the Urine of Healthy People and Patients with Infectious Diseases

Park S, Kim ET, Huh JS

There has been a sustained effort to overcome the multiple infectious diseases that confront humankind. Urinary tract infections (UTIs) are most commonly caused by bacterial pathogens, primarily Escherichia coli. However,...
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A “Prime and Deploy” Strategy for Universal Influenza Vaccine Targeting Nucleoprotein Induces Lung-Resident Memory CD8 T cells

Chung H, Kim EA, Chang J

Lung-resident memory T cells (TRM ) play an essential role in protecting against pulmonary virus infection. Parenteral administration of DNA vaccine is generally not sufficient to induce lung CD8 T...
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Updates on Coronavirus Disease 19 Vaccine and Its Clinical Application

Ahn SH, Lee SH

The global epidemic of COVID-19 (coronavirus disease 2019), which began at the end of 2019, is currently in progress, and the largest number of confirmed cases in the Republic of...
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The laboratory test procedure to confirm rotavirus vaccine infection in severe complex immunodeficiency patients

Chae SJ, Cho SR, Choi W, Han MG, Lee DY

The rotavirus vaccine is a live vaccine, and there is a possibility of infection by the virus strain used in the vaccine. We investigated the process of determining whether an...
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Diagnostic Evaluation of the BioFire ® Meningitis/Encephalitis Panel: A Pilot Study Including Febrile Infants Younger than 90 Days

Kim KM, Park JY, Park KU, Sohn YJ, Choi YY, Han MS, Choi EH

Purpose: Rapid detection of etiologic organisms is crucial for initiating appropriate therapy in patients with central nervous system (CNS) infection. This study aimed to evaluate the diagnostic value of the...
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Monocytes Contribute to IFN-β Production via the MyD88-Dependent Pathway and Cytotoxic T-Cell Responses against Mucosal Respiratory Syncytial Virus Infection

Kim TH, Kim CW, Oh DS, Jung HE, Lee HK

Respiratory syncytial virus (RSV) is the leading cause of respiratory viral infection in infants and children. However, little is known about the contribution of monocytes to antiviral responses against RSV...
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