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Living donor liver transplantation in an infant patient with progressive familial intrahepatic cholestasis along with hepatocellular carcinoma: a case report

Namgoong JM, Hwang S, Kim DY, Ahn CS, Kwon H, Ha S, Kim KM, Oh SH

Progressive familial intrahepatic cholestasis (PFIC) is an autosomal recessive inherited disease requiring liver transplantation (LT). Hepatocellular carcinoma (HCC) is very rare in infants. We present a case of living donor...
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Validation for models for tumor recurrence after liver transplantation in hepatectomy patients

Kim SJ, Kim JM, Yi NJ, Choi GS, Lee KW, Suh KS, Joh JW

Purpose: Early recurrence of hepatocellular carcinoma (HCC) remains a challenging issue after hepatic resection (HR) because of the associated poor prognosis. Models for tumor recurrence after liver transplantation (MoRAL) have...
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Salvage living donor liver transplantation for post-resection recurrence of combined hepatocellular carcinoma-cholangiocarcinoma

Kim M, Hwang S, Song GW, Ahn CS, Moon DB, Jung DH, Park GC, Lee SG

Salvage liver transplantation (LT) is a definite treatment for recurrent hepatocellular carcinoma (HCC) after hepatectomy. Combined hepatocellular carcinoma-cholangiocarcinoma (cHCC-CC) is not eligibly indicated for LT because of high post-transplant recurrence....
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Performances of CYFRA 21-1, Carcinoembryonic Antigen and Their Combination for Lung Cancer Diagnosis

Kim JJ, Ahn HJ, Park Y

BACKGROUND: The aim of this study was to compare the efficiency of cytokeratin 19 fragment (CYFRA 21-1) and carcinoembryonic antigen (CEA) for the diagnosis of lung cancer and to establish...
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The power of the Risk of Ovarian Malignancy Algorithm considering menopausal status: a comparison with CA 125 and HE4

Han KH, Park NH, Kim JJ, Kim S, Kim HS, Lee M, Song YS

OBJECTIVE: To identify the power of tumor markers for predicting ovarian cancer according to menopausal status. METHODS: The medical records of 876 women with ovarian cysts were retrospectively reviewed. Cancer antigen...
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Serum microRNA-381: A Potential Marker for Early Diagnosis of Gastric Cancer

Li Y, Sun H, Guan J, Ji T, Wang X

PURPOSE: The purpose of this study was to explore the potential early diagnostic value of serum microRNA-381(miRNA-381) in patients with gastric cancer (GC). MATERIALS AND METHODS: Patients with advanced gastric cancer...
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Annual Report on the External Quality Assessment Scheme for Tumor Markers in Korea (2017)

Song SH

In 2017, the tumor marker program of the Korean Association of External Quality Assessment Service was performed for tumor markers I and II. Tumor marker I comprised alpha-fetoprotein (AFP), carcinoembryonic...
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Clinical Usefulness of Human Epididymis Protein 4 in Lung Cancer

Choi SI, Jang MA, Jeon BR, Shin HB, Lee YK, Lee YW

Human epididymis protein 4 (HE4) has been suggested as a useful new biomarker of lung cancer; however, few relevant large-scale studies have been published. In this study, we evaluated the...
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Evaluation of sHLA-G levels in serum of patients with prostate cancer identify as a potential of tumor marker

Heidari MH, Movafagh A, Abdollahifar MA, Abdi S, Barez MM, Azimi H, Moradi A, Bagheri A, Heidari M, Hessam Mohseni J, Tadayon M, Mirsafian , Ghatrehsamani M

Prostate cancer is the most common cancer type in men and is the second cause of death, due to cancer, in patients over 50, after lung cancer. Prostate specific antigen...
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An appraisal of pancreatic cyst fluid molecular markers

Modi RM, Pavurala R, Krishna SG

Pancreatic malignancy is the third leading cause of cancer related death in the United States with limited viable screening options. By the end of this decade, cancers are poised to...
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Annual Report on the External Quality Assessment Scheme for Immunoassay Tests in Korea (2015)

Kim HS, Kim YL, Shim JE, Immunoassay Subcommittee, Korean Association of External Quality Assessment Services

Two trials of external quality assessment were performed in 2015, with 13 test items grouped into four test categories. The first trial materials were sent on May 19, 2015 and...
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Peri-Transplant Change in AFP Level: a Useful Predictor of Hepatocellular Carcinoma Recurrence Following Liver Transplantation

Yoo T, Lee KW, Yi NJ, Choi YR, Kim H, Suh SW, Jeong JH, Lee JM, Suh KS

Pretransplant alpha-fetoprotein (AFP) is a useful tumor marker predicting recurrence of hepatocellular carcinoma (HCC). Little is known, however, about the relationship between changes in AFP concentration and prognosis. This study...
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Delayed radiation-induced inflammation accompanying a marked carbohydrate antigen 19-9 elevation in a patient with resected pancreatic cancer

Mattes MD, Cardinal J, Jacobson G

Although carbohydrate antigen (CA) 19-9 is a useful tumor marker for pancreatic cancer, it can also become elevated from a variety of benign and malignant conditions. Herein we describe an...
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A Case of Nongerminomatous Germ Cell Tumor with Fulminant Course Concomitant Leptomeningeal Metastasis

Jeong YB, Wang KC, Phi JH, Lee JY, Cheon JE, Kang HJ, Kim IH, Kim SK

We present the case of a 9-year-old boy with a non-germinomatous germ cell tumor (NGGCT) in the pineal gland that exhibited a fulminant course following chemo- and radiotherapy. After the...
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Comparison of HE4, CA125, and Risk of Ovarian Malignancy Algorithm in the Prediction of Ovarian Cancer in Korean Women

Cho HY, Park SH, Park YH, Kim HB, Kang JB, Hong SH, Kyung MS

This study is a multi-center clinical study, which aimed to compare CA125, HE4, and risk of ovarian malignancy algorithm (ROMA) in predicting epithelial ovarian cancer of Korean women with a...
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Abnormally high level of CA-19-9 in a benign ovarian cyst

Pyeon SY, Park JY, Ki KD, Lee JM

CA-19-9 antigen is mainly elevated in cases of gastrointestinal tract malignancy, including of the pancreas, colorectum, and biliary tract. CA 19-9 antigen can also be elevated in ovarian mucinous neoplasms,...
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Pretreatment risk factors for parametrial involvement in FIGO stage IB1 cervical cancer

Yamazaki H, Todo Y, Okamoto K, Yamashiro , Kato H

OBJECTIVE: All patients with stage IB1 cervical cancer do not need to undergo parametrectomy. Some low-risk criteria for parametrial involvement (PI) have been proposed based on pathological findings. The aim...
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Diagnostic Utility of Serum Cytokeratin Fragment 21-1 in Patients with Lung Cancer

Song S, Yoo EH, Cho HJ

BACKGROUND: Lung cancer is the most lethal malignant neoplasm in the world. Serum cytokeratin fragment 21-1 (Cyfra 21-1) is a valuable tumor marker for detection of lung cancer, and it...
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Breast Cancer Subtype as a Predictor of Lymph Node Metastasis according to the SEER Registry

Mattes MD, Bhatia JK, Metzger D, Ashamalla , Katsoulakis E

PURPOSE: Breast cancer subtype correlates with response to systemic therapy and overall survival (OS), but its impact on lymphatic spread is incompletely understood. In this study, we used the Surveillance,...
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The Value of Postoperative Serum Carcinoembryonic Antigen and Carbohydrate Antigen 19-9 Levels for the Early Detection of Gastric Cancer Recurrence after Curative Resection

Lee EC, Yang JY, Lee KG, Oh SY, Suh YS, Kong SH, Yang HK, Lee HJ

PURPOSE: This study aimed to evaluate the value of serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) levels to detect gastric cancer recurrence. MATERIALS AND METHODS: We retrospectively reviewed 154...
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