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CLOCC Patient after COVID-19 (BNT162b) Vaccine Improved by Steroid Treatment

Kim H, Kim N, Choi S, Kim Ay, Choi H

Cytotoxic lesions of the corpus callosum (CLOCC) are secondary lesions on corpus callosum caused by cytokinopathy of callosal neurons and microglia. Fever, headache, and digestive disturbances are common symptoms. Reversible...
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MiR-29a-3p Inhibits Proliferation and Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells via Targeting FOXO3 and Repressing Wnt/β-Catenin Signaling in Steroid-Associated Osteonecrosis

Wang C, Zhu M, Yang D, Hu X, Wen X, Liu A

Background and Objectives: This study was to investigate the role of microRNA-29a-3p (miR-29a-3p) in human bone marrow mesenchymal stem cells (hBMSCs), and its relationship with steroid-associated osteonecrosis. Methods and Results: The...
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Intralesional steroid infusion using a spray tube to prevent stenosis after endoscopic submucosal dissection of esophageal cancer

Goto A, Okamoto T, Ogawa R, Hamabe K, Hashimoto S, Nishikawa J, Takami T

Background/Aims: Intralesional steroid injections have been administered as prophylaxis for stenosis after esophageal endoscopic submucosal dissection. However, this method carries a risk of potential complications such as perforation because...
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Sudden Hearing Loss in Patients With COVID-19: Case Series and Analysis of the Literature

Jin MH, Kim MW, Choi JY, Kwak MY

This study reports on patients with severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) presenting with sudden sensorineural hearing loss (SSNHL) during the coronavirus disease 2019 (COVID-19) pandemic. The study included...
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Clinical Characteristics of COVID-19: Use of Steroids in Mostly Unvaccinated COVID-19 Patients Before the Omicron Variant

Oh SM, Ham SY, Suh HJ, Lee E, Park SW

Background: Glucocorticoids are one of the current standard agents for moderate to severe coronavirus disease 2019 (COVID-19) treatment based on the RECOVERY trial. Data on the real clinical application of...
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Evaluation of the efficacy and safety of epidural steroid injection using a nonparticulate steroid, dexamethasone or betamethasone: a double-blind, randomized, crossover, clinical trial

Lee GY, Lee JW, Lee E, Yeom JS, Kim KJ, Shin HI, Kang HS

Background: The U.S. Food and Drug Administration has prohibited epidural steroid injection (ESI) with particulate steroids. Thus, this study aimed to compare the efficacy and safety of ESI with two...
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Risk factors and clinical impact of COVID-19-associated pulmonary aspergillosis: Multicenter retrospective cohort study

Lee R, Cho SY, Lee DG, Ahn H, Choi H, Choi SM, Choi JK, Choi JH, Kim SY, Kim YJ, Lee HJ

Background/Aims: The risk factors and clinical impacts of coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) remain controversial, and no data have been reported in Korea. This study aimed to investigate...
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General Public Knowledge Regarding Topical Corticosteroids: A Nationwide Survey in South Korea

Seo H, Song SY, Kim D, Park JH, Shin Y, Lee KH, Choi SA, Lee JY, Kim DY, Shin WG, Kim E

Background: Topical corticosteroids (TCs) are available both as over-the-counter drugs and prescription medicines at pharmacies. Although they are generally safe drugs, inappropriate and excessive use could result in potential side effects....
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Clinical and radiological outcomes of ultrasound-guided barbotage using a spinal needle and subacromial steroid injection for calcific tendinitis of the shoulder

Lee JP, Kim DS, Han JY, Baik SH, Kwak JW, Kim SH

medicaBackground: Ultrasound (US)-guided techniques reported for the treatment of calcific tendinitis have mostly demonstrated good results. This study investigates the effect of US-guided barbotage using a spinal needle in patients with...
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COX-2 Inhibitor Use as an Early Treatment Option for Knee Osteoarthritis Patients in Korea: A Population-Based Cross-Sectional Study

Cho SK, Choi S, Kim H, Song YJ, Jung SY, Jang EJ, Sung YK

Background: To investigate the use of cyclooxygenase-2 (COX-2) inhibitors as an initial drug treatment for knee osteoarthritis (OA) patients. Methods: From 2013 to 2015, patients with knee OA were identified from...
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Effects of Local Anesthetics With or Without Steroids in High-Volume Transforaminal Epidural Blocks for Lumbar Disc Herniation: A Randomized, Double-Blind, Controlled Trial

Chae JS, Kim Wj, Choi SH

Background: Lumbar transforaminal epidural block (TFEB) is an effective treatment modality for radicular pain due to lumbar disc herniation (LDH). The addition of steroids is more effective than local anesthetic...
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Effect of local steroids on urethral strictures: A systematic review and meta-analysis

Soliman C, Pan HY, Mulholland CJ, Furrer MA, Agarwal DK, Lawrentschuk N, Sathianathen NJ

Purpose: Urethral stricture disease is common and has high associated morbidity and impact on quality-of-life. This systematic review and meta-analysis aims to summarise current evidence on the efficacy of local...
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Risk Factors for Coronavirus Disease 2019 (COVID-19)-Associated Pulmonary Aspergillosis in Critically Ill Patients: A Nationwide, Multicenter, Retrospective Cohort Study

Kim SH, Hong JY, Bae S, Lee H, Wi YM, Ko JH, Kim B, Joo EJ, Seok H, Shi HJ, Yoo JR, Hyun M, Kim Ha, Jang S, Mun SJ, Kim J, Kim MC, Jung DS, Kim SH, Peck KR

Background: Coronavirus disease 2019 (COVID-19) is often accompanied by secondary infections, such as invasive aspergillosis. In this study, risk factors for developing COVID-19-associated pulmonary aspergillosis (CAPA) and their clinical outcomes...
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Determinants of Short-Term Weight Gain Following Surgical Treatment for Craniopharyngioma in Adults

Hong AR, Kim JH, Park SS, Kong SH, Choi HJ, Kim YH, Shin CS

Objective : Craniopharyngiomas (CPs) are associated with hypothalamic damage that causes hypothalamic obesity, however, the mechanisms underlying CP-related postoperative weight gain remain debatable. This study aimed to elucidate whether the...
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Effect of 2–6 weeks of systemic steroids on bone mineral density in children

Kuniyil A, Pal S, Sachdev N, Yadav TP

Background: The use of systemic steroids for 6+ weeks in children is associated with decreased bone mineral content (BMC) and density (BMD). However, the effects of a shorter duration of...
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Adductor canal block versus intra-articular steroid and lidocaine injection for knee osteoarthritis: a randomized controlled study

Ming LH, Chin CS, Yang CT, Suhaimi A

Background: This study aimed to assess the efficacy of the adductor canal block (ACB) in comparison to intra-articular steroid-lidocaine injection (IASLI) to control chronic knee osteoarthritis (KOA) pain. Methods: A randomized,...
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Comparison of ultrasound guided pulsed radiofrequency of genicular nerve with local anesthetic and steroid block for management of osteoarthritis knee pain

Ghai B, Kumar M, Makkar JK, Goni V

Background: To compare ultrasound-guided pulsed radiofrequency (PRF) of the genicular nerve with the genicular nerve block using local anesthetic and steroid for management of osteoarthritis (OA) knee pain. Methods: Thirty patients...
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Steroids in the Management of Preoperative Neurological Deficits in Metastatic Spine Disease: Results From the EPOSO Study

Versteeg AL, Elkaim LM, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Fehlings MG, Lazary A, Clarke MJ, Arnold PM, Bettegowda C, Boriani S, Gokaslan ZL, Fisher CG, Weber MH, AO Spine Knowledge Forum Tumor

Objective: Patients presenting with neurological deficit secondary to metastatic epidural spinal cord compression (MESCC) are often treated with surgery in combination with high-dose corticosteroids. Despite steroids being commonly used, the...
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Steroid injection using tendon excursion for trigger finger: introduction to injection methods and analysis of treatment results

Ko SH, Kim DE, Lee TJ

Purpose: Local corticosteroid injections are routinely used as first-line treatment for trigger finger. However, accurate delivery of steroids into the tendon sheath is important for the effectiveness of the treatment...
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Evaluation of Effectiveness of Stellate Ganglion Block Treatment of Sudden Sensorineural Hearing Loss

Han SY, Lee J, Koo H, Chung J

Background and Objectives Sudden sensorineural hearing loss (SSNHL) is characterized by sudden onset of impaired hearing, and systemic steroid is the most widely accepted treatment option for it. The aim...
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