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Effect of Pertussis Toxin and Herbimycin A on Proteinase-Activated Receptor 2-Mediated Cyclooxygenase 2 Expression in Helicobacter pylori-Infected Gastric Epithelial AGS Cells

Seo JH, Seo JY, Chung HY, Kim H

Helicobacter pylori (H. pylori) is an important risk factor for chronic gastritis, peptic ulcer, and gastric cancer. Proteinase-activated receptor 2 (PAR2), subgroup of G-protein coupled receptor family, is highly expressed...
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Involvement of betaPIX in angiotensin II-induced migration of vascular smooth muscle cells

Shin EY, Lee CS, Park MH, Kim DJ, Kwak SJ, Kim EG

Angiotensin II (Ang II) stimulates migration of vascular smooth muscle cell (VSMC) in addition to its contribution to contraction and hypertrophy. It is well established that Rho GTPases regulate cellular...
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Activation of epidermal growth factor receptor is responsible for pervanadate-induced phospholipase D activation

Kim YR, Cha HY, Lim K, Hwang BD, Hoe KL, Namgung U, Park SK

  • KMID: 1097260
  • Exp Mol Med.
  • 2003 Apr;35(2):118-124.
Pervanadate, a complex of vanadate and H2O2, has an insulin mimetic effect, and acts as an inhibitor of protein tyrosine phosphatase. Pervanadate-induced phospholipase D (PLD) activation is known to be...
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