- A case of X-linked agammaglobulinemia with deletion of introns 15-18 of Btk gene mediated by Alu-Alu recombination
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Lee HJ, Ko JS, Kwon SS, Yoo JH, Min JK
- KMID: 2252751
- Korean J Med.
- 2003 Nov;65(Suppl 3):S798-S804.
X-linked agammaglobulinemia (XLA) is characterized by early onset of recurrent bacterial infection, markedly reduced levels of all major classes of immunoglobulins in the serum and few mature B cells in... -
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- Molecular Screening and Analysis of Ligand Proteins Association with Unique - SH3 Domain of c - Yes
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Kwak SJ, Seong YS
- KMID: 2329131
- J Korean Cancer Assoc.
- 1998 Apr;30(2):394-401.
No abstract available. -
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- Fyn Tyrosine Kinase-mediated Tyrosine Phosphorylation of Roundabout (Robo), the Slit Receptor
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Jeon ES, Bae KW, Park HT
- KMID: 2224507
- Korean J Anat.
- 2004 Jun;37(3):275-281.
In this study, the molecular mechanism of tyrosine phosphorylation of Roundabout (Robo), the transmembrane receptor for slits, was investigated. The tyrosine phosphorylation of intracellular portion of Robo was increased by... -
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- Production and characterization of monoclonal antibodies against amphiphysins
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Jin YL, Kim KY, Soung NK, Shin EY, Kim EG, Kim SR
- KMID: 1085742
- Exp Mol Med.
- 2001 Jun;33(2):69-75.
Amphiphysin I and II, proteins enriched in nerve terminals, form heterodimers and interact with dynamin and synaptojanin through their Src homology 3 (SH3) domain. In order to study the expression... -
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- Inositol 5'-phosphatase, SHIP1 interacts with phospholipase C-gamma1 and modulates EGF-induced PLC activity
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Song M, Kim MJ, Ha S, Park JB, Ryu SH, Suh PG
- KMID: 1056227
- Exp Mol Med.
- 2005 Jun;37(3):161-168.
Phospholipase C-gamma1, containing two SH2 and one SH3 domains which participate in the interaction between signaling molecules, plays a significant role in the growth factor-induced signal transduction. However, the role... -
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- A Study on the Proteins that Interact with Human Nebulin SH3 Domain
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Choi SH, Ko HS, Kim DW
- KMID: 2104901
- J Korean Orthop Res Soc.
- 2002 Oct;5(2):133-139.
OBJECTIVE: bjective: By identifying the unknown substance responsible for binding with nebulin SH3 domain within the sarcomeric Z-line, we tried to find out Z-line structure which plays an important role... -
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- Cell-free expression and functional reconstitution of CALM in clathrin assembly
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Kim JA, Kim HL
- KMID: 1085745
- Exp Mol Med.
- 2001 Jun;33(2):89-94.
Clathrin-mediated vesicle formation is an essential step in the intracellular trafficking of the protein and lipid. Binding of clathrin assembly protein to clathrin triskelia induces their assembly into clathrin-coated vesicles... -
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- Properties of GST-CALM expressed in E. coli
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Kim JA, Kim SR, Jung YK, Woo SY, Seoh JY, Hong YS, Kim HL
- KMID: 1109309
- Exp Mol Med.
- 2000 Jun;32(2):93-99.
Clathrin-coated vesicles (CCVs) are involved in protein and lipid trafficking between intracellular compartments in eukaryotic cells. CCVs are composed of clathrin and assembly proteins. The clathrin assembly protein lymphoid... -
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- Basic fibroblast growth factor-induced translocation of p21-activated kinase to the membrane is independent of phospholipase C-gamma1 in the differentiation of PC12 cells
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Shin KS, Shin EY, Lee CS, Quan SH, Woo KN, Soung NK, Kwak SJ, Kim SR, Kim EG
- KMID: 1081468
- Exp Mol Med.
- 2002 May;34(2):172-176.
p21-activated kinase (PAK) targeting to the plasma membrane is essential for PC12 cell neurite outgrowth. Phospholipase C-gamma1 (PLC-gamma1) can mediate the PAK translocation in response to growth factors, since PLC-gamma1... -
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- Characteristics of the Molecular Interaction of Adaptor Proteins in Protein Tyrosine Kinase Cascades
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Park YK, Choi SJ, Park RK, Chung SY, Kim SK
- KMID: 2048558
- Chonnam Med J.
- 1998 Dec;34(2):157-176.
Recent evidence suggests that FcgammaR and FcgammaR receptors signal through the low molecular weight GTPase, Ras. Ras is regulated by the nucleotide exchange protein, Sos, via formation of Grb2/Sos complex.... -
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- Distinct Regional and Cellular Localization of Hyperpolarization-activated Cyclic Nucleotide-gated Channel 1 in Cerebellar Cortex of Rat
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Kwon YJ, Kim TS
- KMID: 2067279
- J Korean Neurosurg Soc.
- 2007 Sep;42(3):205-210.
OBJECTIVE: Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels mediate the hyperpolarizationactivated currents (Ih) that participate in regulating neuronal membrane potential and contribute critically to pacemaker activity, promoting synchronization of neuronal networks. However,... -
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- Gene expression after the application of the fluid-induced shear stress on the gingival fibroblast
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Jeong MH, Choi JY, Chae CH, Kim SG, Nahm DS
- KMID: 2005030
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2005 Sep;27(5):424-430.
The oral cavity is humid environment mainly due to the continuous salivary flow. The reaction of oral mucosa to fluid flow is important for homeostasis and pathogenesis. The objective of... -
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