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A Human Immunodeficiency Virus Type 1 (HIV-1) Tat Cofactor Absent in Rodent Cells is a TAR-associated Factor

Lee IS, Shank PR

BACKGROUND: Although Tat plays a role as a potent transactivator in the viral gene expression from the Human Immunodeficiency Virus type 1 long terminal repeat (HIV-1 LTR), it does not...
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Empathy Study in Rodent Model of Autism Spectrum Disorders

Mony TJ, Hong M, Lee HJ

There is a highly cognitive and social context to empathy behavior in human. In various social contexts, rodents also display remarkable affective sensitivity and exhibit primitive forms of empathy similar...
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Seasonal distribution of chigger mites in the Kanghwa Island and Yongjong Island

Lee IY, Yoon SS, Ree HI

Seasonal distribution of chigger mites in the Kangwha Island and Yongjong Island was studied during the period of October 1992-August 1993. From 42 field rodents collected, 1,290 chiggers were obtained...
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Involvement of immune responses in pulmonary arterial hypertension; lessons from rodent models

Kim K, Choi JH

Pulmonary hypertension (PH) is a pathological state with sustained elevation of pulmonary artery (PA) pressure. Since the pathogenesis of PH is mostly irreversible, the disease often comes up with poor...
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Role of p11 (S100A10) in Depression and Antidepressant Effects

Park SW, Seo MK, Lee JG, Kim YH

p11 protein (S100A10) is downregulated in depressive-like states of human and rodent. Antidepressant drug treatment increases p11 levels in rodent models. We reviewed studies demonstrating that p11 levels are regulated...
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Rodent Models of Diet-induced Obesity

Koh G

The prevalence of obesity is rapidly increasing worldwide, and its complications such as type 2 diabetes and cardiovascular disease are also increasing. To avoid long-term damage caused by obesity and...
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Isolation of the Hantaviruses from the Lungs of Bandicota indica Captured in Indonesia and Thailand

Woo YD, Chu YK, Lee HW

  • KMID: 1551977
  • J Korean Soc Virol.
  • 1998 Jun;28(2):157-164.
Various hantaviruses were isolated from HFRS patients and various rodent species, in many parts of the world. Bandicotas were captured at Yogyakarta, east region of Sumatura island, Indonesia; and 4...
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Application of Developmental Principles for Functional Regeneration of Salivary Glands

Lee ES, Adhikari N, Jung JK, An CH, Kim JY, Kim JY

Currently, there has been rapid increase in the studies about salivary production because of the hyposalivation, xerostomia, caused by radiotherapy for head and neck cancer, Sjogren syndrome and aging. An...
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Spontaneous and transgenic rodent models of inflammatory bowel disease

Prattis S, Jurjus A

Inflammatory Bowel Disease (IBD) is a multifactorial disorder with many different putative influences mediating disease onset, severity, progression and diminution. Spontaneous natural IBD is classically expressed as Crohn's Disease (CD)...
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Susceptibility of Laboratory Rodents to Trichinella papuae

Sadaow L, Intapan PM, Boonmars T, Morakote N, Maleewong

Members of the genus Trichinella are small nematodes that can infect a wide range of animal hosts. However, their infectivity varies depending on the parasite and host species combination. In...
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Hemorrhagic Fever with Renal Syndrome

Kim HY

Hemorrhagic fever with renal syndrome (HFRS) is an acute febrile illness caused by Eurasian hantaviruses and characterized by renal insufficiency, hemorrhage, thrombocytopenia, and shock. Each hantavirus is primarily associated with...
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Mathematical Modeling for Scrub Typhus and Its Implications for Disease Control

Min KD, Cho SI

BACKGROUND: The incidence rate of scrub typhus has been increasing in the Republic of Korea. Previous studies have suggested that this trend may have resulted from the effects of climate...
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Pharmacokinetics and cytotoxic effect of selenium compounds in rodent cancer xenograft model for therapy experiment

Hwang JY

No abstract available.
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Phylogenetic Relationships and co-evolution Between Hantaan Virus and Rodent Host , Striped-field Mice ( Apodemus agrarius ) by Mitochondrial DNA Sequences

Lee YJ, Baek LJ, Song KJ, Kim SH, Yun JK, Song JW, Choi JE

  • KMID: 1943431
  • J Korean Soc Microbiol.
  • 1999 Apr;34(2):163-174.
Hantaviruses, members of the family Bunyaviridae, are causative agents of hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Hantaan (HTN) virus, the etiologic agent of clinically severe...
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Mechanisms of postoperative pain

Kang S, Brennan TJ

Good pain control after surgery is important to facilitate overall recovery, improve patient satisfaction, decrease morbidity, and reduce health care cost. However, despite heightened awareness and development of new guidelines...
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Epidemiological studies on host animals of tsutsugamushi disease in Korea

Ree HI, Lee HS, Lee IY, Yoshida Y

Epidemiological studies on host rodents of tsutsugamushi disease were carried out during the period of July-September 1990 at nine localities of central Korea. Among total 111 wild rodents trapped by...
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Comparative bioinformatics analysis of prion proteins isolated from reptile, rodent, ruminant, and human species

Ahn I, Son HS

  • KMID: 1091071
  • Exp Mol Med.
  • 2007 Dec;39(6):769-777.
Prion proteins (PrPs) are infectious pathogens that cause a group of invariably fatal, neurodegenerative diseases, including Creutzfeldt-Jakob disease, by means of an entirely novel mechanism. They are produced by various...
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Genetic Analysis of Hantaviral M Segment Isolated from Patients with Korean Hemorrhagic Fever

Cho JT, Yoon SC, Ahn CR, Han JS, Kim SG, Lee JS

  • KMID: 2254666
  • Korean J Nephrol.
  • 1998 Mar;17(2):189-200.
Hemorrhagic fever with renal syndrome(HFRS) is an infectious disease showing diverse clinical manifestations according to different serotypes of hantavirus. Korean hemorrhagic fever(KHF), HFRS caused by Hantaan or Seoul virus in...
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Apodemus agrarius as a new definitive host for Neodiplostomum seoulense

Chai JY, Park JH, Guk SM, Kim JL, Kim HJ, Kim WH, Shin EH, Klein TA, Kim HC, Chong ST, Song JW, Baek LJ

A total of 1,496 rodents and insectivores were live-trapped at Yeoncheon-gun (n = 351), Paju-shi (804), and Pocheon-gun (343), Gyeonggi-do (Province), and examined for intestinal helminths, including Neodiplostomum seoulense, seasonally...
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Histological Investigation of the Appetite Center in Ginseng-administered Mice

Chung HY

  • KMID: 2424919
  • J Korean Neurosurg Soc.
  • 1976 Jun;5(1):11-20.
Tremendous studies have been accumulated on the tonic effects of the ginseng to date. They are temporary effects on the heart, blood, kidney, liver, spleen etc. during the ginseng-administered period....
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