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G protein signaling in the parasite Entamoeba histolytica

Bosch DE, Siderovski DP

  • KMID: 2154234
  • Exp Mol Med.
  • 2013 Mar;45(3):e15.
The parasite Entamoeba histolytica causes amebic colitis and systemic amebiasis. Among the known amebic factors contributing to pathogenesis are signaling pathways involving heterotrimeric and Ras superfamily G proteins. Here, we...
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Role of Ras/ERK-dependent pathway in the erythroid differentiation of K562 cells

Kang CD, Do IR, Kim KW, Ahn BK, Kim SH, Chung BS, Jhun BH, Yoo MA

  • KMID: 1029935
  • Exp Mol Med.
  • 1999 Jun;31(2):76-82.
The chronic myelogenous leukemic K562 cell line carrying Bcr-Abl tyrosine kinase is considered as pluripotent hematopoietic progenitor cells expressing markers for erythroid, granulocytic, monocytic, and megakaryocytic lineages. Here we investigated the signaling modulations...
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