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Pathogenesis and Management of Serrated Polyps: Current Status and Future Directions

Anderson J

Hyperplastic or serrated polyps were once believed to have little to no clinical significance. A subset of these polyps are now considered to be precursors to colorectal cancers (CRC) in...
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Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway

Moon BS, Yoon JY, Kim MY, Lee SH, Choi T, Choi KY

Bone morphogenic protein 4 (BMP4), a member of the TGF-beta superfamily, induced neural differentiation of neural stem cells (NSCs) grown in a medium containing basic fibroblast growth factor (bFGF). The...
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Cellular characteristics of primary and immortal canine embryonic fibroblast cells

You S, Moon JH, Kim TK, Kim SC, Kim JW, Yoon DH, Kwak S, Hong KC, Choi YJ, Kim H

  • KMID: 1094076
  • Exp Mol Med.
  • 2004 Aug;36(4):325-335.
Using normal canine embryonic fibroblasts (CaEF) that were shown to be senescent at passages 7th-9th, we established two spontaneously immortalized CaEF cell lines (designated CGFR-Ca-1 and -2) from normal senescent...
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Chemotherapy for Colorectal Cancer

Hong YS, Kim TW

Recent advances in chemotherapy lead to improved survival outcomes in patients with colorectal cancer. The 5-fluorouracil (5-FU) is still one of the important chemotherapeutic agents since 1950s, but the introduction...
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