- ANT2 suppression by shRNA restores miR-636 expression, thereby downregulating Ras and inhibiting tumorigenesis of hepatocellular carcinoma
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Jang JY, Lee YS, Jeon YK, Lee K, Jang JJ, Kim CW
- KMID: 2154222
- Exp Mol Med.
- 2013 Jan;45(1):e3.
MicroRNAs (miRNAs) participate in diverse biological functions and carcinogenesis by inhibiting specific gene expression. We previously reported that suppression of adenine nucleotide translocase 2 (ANT2) by using the short hairpin... -
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- Activation of KRAS promotes the mesenchymal features of basal-type breast cancer
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Kim RK, Suh Y, Yoo KC, Cui YH, Kim H, Kim MJ, Kim IG, Lee SJ
- KMID: 2155402
- Exp Mol Med.
- 2015 Jan;47(1):e137.
- doi: 10.1038/emm.2014.99
Basal-type breast cancers are among the most aggressive and deadly breast cancer subtypes, displaying a high metastatic ability associated with mesenchymal features. However, the molecular mechanisms underlying the maintenance of... -
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- LIN28B confers radio-resistance through the posttranscriptional control of KRAS
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Jeong SH, Wu HG, Park WY
- KMID: 1099867
- Exp Mol Med.
- 2009 Dec;41(12):912-918.
- doi: 10.3858/emm.2009.41.12.097
To screen the differentially expressed microRNAs related to radio-resistance, we compared the microRNA profiles of lung cancer cells with different responses to ionizing radiation (IR). Of 328 microRNAs in microarray,... -
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- Detection of EGFR and KRAS Mutation by Pyrosequencing Analysis in Cytologic Samples of Non-Small Cell Lung Cancer
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Lee SE, Lee SY, Park HK, Oh SY, Kim HJ, Lee KY, Kim WS
- KMID: 2373749
- J Korean Med Sci.
- 2016 Aug;31(8):1224-1230.
- doi: 10.3346/jkms.2016.31.8.1224
EGFR and KRAS mutations are two of the most common mutations that are present in lung cancer. Screening and detecting these mutations are of issue these days, and many different... -
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