- Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway
-
Shin DH, Kim OH, Jun HS, Kang MK
- KMID: 1104802
- Exp Mol Med.
- 2008 Oct;40(5):486-494.
- doi: 10.3858/emm.2008.40.5.486
Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), the major pungent ingredient of red pepper, has been reported to possess anti-carcinogenic and anti-mutagenic activities. In this study, the anti-migration activity of capsaicin on highly metastatic B16-F10... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibition of rac1 Reduces PDGF-induced Reactive Oxygen Species and Proliferation in Vascular Smooth Muscle Cells
-
Kong G, Lee S, Kim KS
- KMID: 648350
- J Korean Med Sci.
- 2001 Dec;16(6):712-718.
- doi: 10.3346/jkms.2001.16.6.712
In vascular smooth muscle cells, reactive oxygen species (ROS) were known to mediate platelet-derived growth factor (PDGF)-induced cell proliferation and NADH/NADPH oxidase is the major source of ROS. NADH/NADPH oxidase... -
- CITED
-
- Close
- SHARE
-
- Close
- Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
-
Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W
- KMID: 2471880
- Nutr Res Pract.
- 2020 Apr;14(2):127-133.
- doi: 10.4162/nrp.2020.14.2.127
BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found... -
- CITED
-
- Close
- SHARE
-
- Close
- The reno-protective effect of a phosphoinositide 3-kinase inhibitor wortmannin on streptozotocin-induced proteinuric renal disease rats
-
Kim SH, Jang YW, Hwang P, Kim HJ, Han GY, Kim CW
- KMID: 1120141
- Exp Mol Med.
- 2012 Jan;44(1):45-51.
- doi: 10.3858/emm.2012.44.1.004
Diabetic nephropathy (DN) is a progressive kidney disease that is caused by injury to kidney glomeruli. Podocytes are glomerular epithelial cells and play critical roles in the glomerular filtration barrier.... -
- CITED
-
- Close
- SHARE
-
- Close
- Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression
-
Wang Z, Jin H, Xu R, Mei Q, Fan D
- KMID: 1009393
- Exp Mol Med.
- 2009 Oct;41(10):717-727.
- doi: 10.3858/emm.2009.41.10.078
Triptolide, a diterpenoid triepoxide from the traditional Chinese medicinal herb Tripterygium wilfordii Hook. f., is a potential treatment for autoimmune diseases as well a possible anti-tumor agent. It inhibits proliferation... -
- CITED
-
- Close
- SHARE
-
- Close
- Involvement of betaPIX in angiotensin II-induced migration of vascular smooth muscle cells
-
Shin EY, Lee CS, Park MH, Kim DJ, Kwak SJ, Kim EG
- KMID: 756231
- Exp Mol Med.
- 2009 Jun;41(6):387-396.
- doi: 10.3858/emm.2009.41.6.044
Angiotensin II (Ang II) stimulates migration of vascular smooth muscle cell (VSMC) in addition to its contribution to contraction and hypertrophy. It is well established that Rho GTPases regulate cellular... -
- CITED
-
- Close
- SHARE
-
- Close
- Reactive oxygen species regulate the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocyte growth factor
-
Lee KH, Kim JR
- KMID: 1123465
- Exp Mol Med.
- 2009 Mar;41(3):180-188.
- doi: 10.3858/emm.2009.41.3.021
Tumor cells are known to produce larger amounts of reactive oxygen species (ROS) than normal cells. Although numerous reports have indicated the importance of ROS in urokinase plasminogen activator (uPA)... -
- CITED
-
- Close
- SHARE
-
- Close
