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Expression of p73 in Non-small Cell Lung Carcinomas

Jung JH, Park G, Jung CK, Choi HJ, Yoo J, Kang SJ, Lee KY

  • KMID: 2073780
  • Korean J Pathol.
  • 2007 Apr;41(2):109-115.
BACKGROUND: The p73 is a recently identified homologue of the tumor suppressor gene, p53, and it has been found to induce apoptosis and inhibit cell proliferation. However, its role in...
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Elevated Expression of p73 and Its Relation to VEGF and TSP-1 Production in Cervical Carcinoma

Seo SG, Lee SK, Kim SB, Chi SG

  • KMID: 2013154
  • Korean J Obstet Gynecol.
  • 2006 Mar;49(3):599-610.
OBJECTIVE: Measure the over-expression of p73 and analyze as the prognostic as well as angiogenic factor of cervical cancer by comparing the degree of expression of VEGF and TSP-1 by...
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p73 Methylation in Extranodal NK/T Cell Lympoma

Cho MS

OBJECTIVES: DNA methylation of promoter-associated CpG islands is an epigenetic modification of DNA associanted with gene silencing. p73 is a member of the p 53 family which is a tumor...
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p63 and p73 in Tumor Suppression and Promotion

McKeon FD

  • KMID: 1807301
  • Cancer Res Treat.
  • 2004 Feb;36(1):6-12.
The recent discovery of two genes, termed p63 and p73, encoding transcription factors highly homologous to p53 presents unexpected challenges and opportunities for the understanding and treatment of cancers. The...
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Expression of p53 and p73 Genes in Human Transitional Cell Carcinoma of the Bladder

Choi YD, Park JA, Cho NH, Yang WJ, Cho KS, Lee HY, Hong SJ

  • KMID: 2293227
  • Korean J Urol.
  • 2004 Dec;45(12):1209-1214.
PURPOSE: We analyzed the tissue samples of bladder transitional cell carcinoma (TCCa) for both the p53 and p73 gene, and we attempted to elucidate their possible roles in the pathogenesis...
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Study on mRNA expression of p21 and p73 in the cell lines of primary and metastatic squamous cell carcinoma

Kang JH, Kim KW, Lee JH

  • KMID: 1961181
  • J Korean Assoc Oral Maxillofac Surg.
  • 2001 Dec;27(6):483-490.
There were many controversies in the cause and progress of tumorigenesis. Recently, studies on the mutation of genes related to the tumor have extensively been performed due to development of...
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Expression of p73 in Null-p53 SKOV3 Ovarian Cancer Cell Line

Whang JD, Park CS, Choi JJ, Kim JS, Bae DS, Lee JH

  • KMID: 2083732
  • Korean J Gynecol Oncol Colposc.
  • 1999 Jun;10(2):122-129.
p73, a first p53 relative, has been identified at chromosome 1p36, a region that is deleted in variety of human cancers. This protein shares strong homology with p53 protein, suggesting...
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Loss of Heterozygosity of p73, APC, and p53 in Hepatoblastoma

Kim HS, Jung YM, Kim MR, Lee JY, Lee MS, Jang JJ

  • KMID: 1855229
  • Korean J Hepatol.
  • 1999 Mar;5(1):43-49.
BACKGROUND/AIMS: The status of tumor suppression gene can be assessed indirectly by analyzing the loss of heterozygosity. Hepatoblastoma is a malignant liver tumor in childhood. To find the molecular carcinogenetic mechanism of...
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Inactivation of p73 Protein by Cervical Cancer-inducing HPV E6 Protein Novel p53-independent function of E6

Namkoong S, Kim SJ, Kim EJ, Um SJ, Park JS

  • KMID: 2026746
  • Korean J Obstet Gynecol.
  • 1998 Nov;41(11):2827-2834.
OBJECTIVE: Human papillomavirus (HPV) is strongly implicated as a causative agent in the etiology of cervical cancer. Of its gene products, E6 and E7 oncoproteins play major roles by inactivation...
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