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Zinc modulation of osterix in MC3T3-E1 cells

Seo HJ, Jeong JB, Cho YE, Kwun IS

Purpose: Zinc is known to be associated with osteoblast proliferation and differentiation. Osterix as zinc-finger transcription factor is also related to osteoblast differentiation and bone formation. In the present study, we...
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LC/MS-based Analysis of Bioactive Compounds from the Bark of Betula platyphylla var. japonica and Their Effects on Regulation of Adipocyte and Osteoblast Differentiation

Baek SC, Choi E, Eom HJ, Jo MS, Kim S, So HM, Kim SH, Kang KS, Kim KH

Betula platyphylla var. japonica (Betulaceae), also known as Asian white birch, is an endemic medicinal tree, the bark of which has been used in Chinese traditional medicine for the treatment...
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Cellular zinc deficiency inhibits the mineralized nodule formation and downregulates bone-specific gene expression in osteoblastic MC3T3-E1 cells

Cho YE, Kwun IS

PURPOSE: Zinc (Zn) is an essential trace element for bone mineralization and osteoblast function. We examined the effects of Zn deficiency on osteoblast differentiation and mineralization in MC3T3-E1 cells. METHODS: Osteoblastic...
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The effect of biomechanical stimulation on osteoblast differentiation of human jaw periosteum-derived stem cells

Lee JM, Kim MG, Byun JH, Kim GC, Ro JH, Hwang DS, Choi BB, Park GC, Kim UK

BACKGROUND: This study was to investigate the effect of biomechanical stimulation on osteoblast differentiation of human periosteal-derived stem cell using the newly developed bioreactor. METHODS: Human periosteal-derived stem cells were harvested...
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Synergistic Effects of Chios Gum Mastic Extract and Low Level Laser Therapy on Osteoblast Differentiation

Lee KH, Kim YS, Yu SB, Kang HM, Kwak HH, Kim IR, Park BS

In the present study, we evaluated the effect of CGM on osteogenic differentiation of cultured osteoblasts, and determined whether combination treatment with LLLT had synergistic effects on osteogenic differentiation. The results...
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Effect of microgrooves and fibronectin conjugation on the osteoblast marker gene expression and differentiation

Park SJ, Leesungbok R, Ahn SJ, Im BJ, Lee DY, Jee YJ, Yoon JH, Cui T, Lee SC, Lee SW

PURPOSE: To determine the effect of fibronectin (FN)-conjugated, microgrooved titanium (Ti) on osteoblast differentiation and gene expression in human bone marrow-derived mesenchymal stem cells (MSCs). MATERIALS AND METHODS: Photolithography was used...
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Lactoferrin Constitutively Enhances Differentiation of Osteoblastic MC3T3-E1 Cells in Vitro

Yang HY, Lee HM, Park BJ, Lee TH

  • KMID: 1727432
  • Int J Oral Biol.
  • 2014 Sep;39(3):145-151.
During bone remodeling, there is requirement of differentiation of osteoblastic cells. Previously, we identified proteins differentially expressed in soft tissue during bone healing. Of these proteins, we focused the effect...
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Effects of Bisphosphonates on the Proliferation and the Alkaline Phosphatase Activity of Human Bone Marrow Derived Mesenchymal Stem Cells

Jung J, Lee B, Kwon YD, Ohe JY, Kim YR

  • KMID: 2136911
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Jan;33(1):10-18.
PURPOSE: The purpose of this study is to find out the effects of bisphosphonates (BPs) on the proliferation and the alkaline phosphatase (ALP) activity of human bone marrow derived mesenchymal...
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Osteoblast differentiation of human bone marrow stromal cells (hBMSC) according to age for bone tissue engineering

Song GA, Ryoo HM, Choi JY

Tissue engineered bone (TEB) can replace an autogenous bone graft requiring an secondary operation site as well as avoid complications like inflammation or infection from xenogenic or synthetic bone graft....
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Influence Of Co-Cultured Fibroblasts On The Differentiation Of Mouse Calvaria-Derived Undifferentiated Mesenchymal Cells In Vitro

Hwang YS, Kim MR

  • KMID: 1961159
  • J Korean Assoc Oral Maxillofac Surg.
  • 2002 Apr;28(2):114-125.
This study was designed to evaluate the influence of fibroblasts or connective tissue from mouse oral mucosa on differentiation of neonatal mouse calvaria-derived osteoblasts and mineralization of bone nodules. Primary...
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Interaction of TGF-beta1 and rhBMP-2 on Human Bone Marrow Stromal Cells Cultured in Collagen Gel Matrix

Kim MK, Niyibizi C

Transforming growth factor-beta1 (TGF-beta1) and bone morphogenetic protein-2 (BMP-2) are abundant proteins in the bone matrix. However, their interaction in controlling osteoblast differentiation is not clearly understood. In this study,...
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The Effects of Deer(Cervus nippon) Antler Extracts on Differentiation of MC3T3 Cells

Yoo YJ, Lee HJ, Lim SH, Kang JH, Li YJ, Ohk SH, Choi BK, Jhon GJ

Deer antler has been widely prescribed in Chinese and Korean pharmacology. Although there have been several reports concerning the effects of deer antler, such as anti-aging action, anti-inflammatory activity, antifungal...
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