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Suppression of Peripheral Sympathetic Activity Underlies Protease-Activated Receptor 2-Mediated Hypotension

Kim YH, Ahn DS, Joeng JH, Chung S

Protease-activated receptor (PAR)-2 is expressed in endothelial cells and vascular smooth muscle cells. It plays a crucial role in regulating blood pressure via the modulation of peripheral vascular tone. Although...
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Influence of omega-Conotoxin GVIA, Nifedipine and Cilnidipine on Catecholamine Release in the Rat Adrenal Medulla

Yu BS, Kim BC, Lim DY

  • KMID: 1512914
  • Korean J Physiol Pharmacol.
  • 2007 Feb;11(1):21-30.
The present study was designed to establish comparatively the inhibitory effects of cilnidipine (CNP), nifedipine (NIF), and omega-conotoxin GVIA (CTX) on the release of CA evoked by cholinergic stimulation...
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Calcium Ions are Involved in Modulation of Melittin-induced Nociception in Rat: I. Effect of Voltage-gated Calcium Channel Antagonist

Shin HK, Le KH

  • KMID: 2071634
  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):255-261.
Melittin-induced nociceptive responses are mediated by selective activation of capsaicin-sensitive primary afferent fibers and are modulated by excitatory amino acid receptor, cyclooxygenase, protein kinase C and serotonin receptor. The present...
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Influence of Cilnidipine on Catecholamine Release in the Perfused Rat Adrenal Medulla

Woo SC, Baek YJ, Lim DY

  • KMID: 1611430
  • Korean J Physiol Pharmacol.
  • 2004 Oct;8(5):265-272.
The present study was attempted to investigate the effect of cilnidipine (FRC-8635), which is a newly synthesized novel dihydropyridine (DHP) type of organic Ca2 channel blockers, on secretion of catecholamines...
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Nimodipine as a potential pharmacological tool for characterizing R-type calcium currents

Oh SB

  • KMID: 1607140
  • Korean J Physiol Pharmacol.
  • 2001 Dec;5(6):511-519.
Nimopidine, one of dihydropyridine derivatives, has been widely used to pharmacologically identify L-type Ca currents. In this study, it was tested if nimodipine is a selective blocker for L-type Ca...
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Calcium channel blockers suppress the responses of rat dorsal horn cell to nociceptive input

Shin HK, Kang SH, Kim KS

  • KMID: 2285180
  • Korean J Physiol Pharmacol.
  • 1997 Dec;1(6):625-637.
Calcium ions are implicated in a variety of physiological functions, including enzyme activity, membrane excitability, neurotransmitter release, and synaptic transmission, etc. Calcium antagonists have been known to be effective for the treatment of...
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