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Immune Characterization of Bone Marrow-Derived Models of Mucosal and Connective Tissue Mast Cells

Benedé S, Cody E, Agashe C, Berin MC

PURPOSE: It is well appreciated that mast cells (MCs) demonstrate tissue-specific imprinting, with different biochemical and functional properties between connective tissue MCs (CTMCs) and mucosal MCs (MMCs). Although in vitro...
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New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development

Kurashima , Kiyono H

To achieve immune homeostasis in such a harsh environment as the intestinal mucosa, both active and quiescent immunity operate simultaneously. Disruption of gut immune homeostasis leads to the development of...
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