- Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model
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Ayyappan J, lizardo K, Wang S, Yurkow E, Nagajyothi JF
- KMID: 2455094
- Biomol Ther.
- 2019 Jul;27(4):386-394.
- doi: 10.4062/biomolther.2018.193
Trypanosoma cruzi infection results in debilitating cardiomyopathy, which is a major cause of mortality and morbidity in the endemic regions of Chagas disease (CD). The pathogenesis of Chagasic cardiomyopathy (CCM)... -
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