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High Cell-Free DNA Levels in Cerebrospinal Fluid Predict Leptomeningeal Seeding of Hematologic Malignancy

Kim EY, Lee ST, Kim YS, Byun JM, Hong J, Shin DY, Koh Y, Kim I

Background and Purpose: The main difficulty when diagnosing leptomeningeal metastases (LMSs) is the low sensitivity of cytology. Cancer cells release cell-free DNA (cfDNA) during proliferation and apoptosis, and so we...
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Comparison of Contrast-Enhanced T2 FLAIR and 3D T1 Black-Blood Fast Spin-Echo for Detection of Leptomeningeal Metastases

Park YW, Ahn SJ

PURPOSE: Imaging plays a significant role in diagnosing leptomeningeal metastases. However, the most appropriate sequence for the detection of leptomeningeal metastases has yet to be determined. This study compares the...
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Impact of Multimodality Approach for Patients with Leptomeningeal Metastases from Solid Tumors

Kwon J, Chie EK, Kim K, Kim HJ, Wu HG, Kim IH, Oh DY, Lee SH, Kim DW, Im SA, Kim TY, Heo DS, Bang YJ, Ha SW

The purpose of this study was to evaluate treatment patterns, outcome and prognosticators for patients with leptomeningeal metastases from solid tumor. Medical records of 80 patients from January 1, 2004...
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A Suspected Case of Metastatic Tumors Involving Both Internal Auditory Canals

Cho YS, Kwon JK, Hong SH, Roh JR

  • KMID: 1886955
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 May;42(5):643-646.
Malignant leptomeningeal metastases involving both internal auditory canals (IACs) are rare and can mimic neurofibromatosis type 2 (NF2). Rapid progression of symptoms and involvement of facial nerve are characteristic clinical...
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