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Cynomolgus Macaque Model for COVID-19 Delta Variant

Baek SH, Oh H, Koo BS, Kim G, Hwang EH, Jung H, An YJ, Park JH, Hong JJ

With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, which are randomly mutated, the dominant strains in regions are changing globally. The development of preclinical animal models...
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Clinical, virological, imaging and pathological findings in a SARS CoV-2 antibody positive cat

Ozer K, Yilmaz A, Carossino M, Ozturk GY, Bamac OE, Tali HE, Mahzunlar E, Cizmecigil UY, Aydin O, Tali HB, Yilmaz SG, Mutlu Z, Kekec AI, Turan N, Gurel A, Balasuriya U, Iqbal M, Richt JA, Yilmaz H

This paper reports a presumptive severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection in a cat. A cat with respiratory disease living with three individuals with coronavirus disease 2019 showed...
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Update in Diagnosis of Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormality

Nam BD, Hwang JH

Idiopathic pulmonary fibrosis (IPF), based on the 2018 international clinical practice guidelines, can be diagnosed with a usual interstitial pneumonia (UIP) pattern on high-resolution computed tomography (HRCT) and compatible clinical...
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Spectrum of Pulmonary Fibrosis from Interstitial Lung Abnormality to Usual Interstitial Pneumonia: Importance of Identification and Quantification of Traction Bronchiectasis in Patient Management

Hino T, Lee KS, Han J, Hata A, Ishigami K, Hatabu H

Following the introduction of a novel pathological concept of usual interstitial pneumonia (UIP) by Liebow and Carrington in 1969, diffuse interstitial pneumonia has evolved into UIP, nonspecific interstitial pneumonia (NSIP),...
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Pleuroparenchymal fibroelastosis in Korean patients: clinico-radiologic-pathologic features and 2-year follow-up

Lee JH, Chae EJ, Song JS, Kim M, Song JW

Background/Aims: Pleuroparenchymal fibroelastosis (PPFE) is a type of rare idiopathic interstitial pneumonia that is characterized by predominantly upper lobe involvement with pleural fibrosis and subjacent parenchymal fibrosis. This study aimed...
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New Era of Management Concept on Pulmonary Fibrosis with Revisiting Framework of Interstitial Lung Diseases

Azuma A, Richeldi L

The disease concept of interstitial lung disease with idiopathic pulmonary fibrosis at its core has been relied on for many years depending on morphological classification. The separation of non-specific interstitial...
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Acute Exacerbation of Idiopathic Pulmonary Fibrosis with Lung Cancer: A Comparative Analysis of the Incidence, Survival Rate, and CT Findings with the Patients without Lung Cancer

Cho B, Kang H, Kim JH, Park JG, Park S, Yun JH

Purpose To compare the incidence, survival rate, and CT findings of acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) between patients with and without lung cancer. Materials and Methods From June...
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Diagnosis and treatment of interstitial lung disease: focusing on idiopathic pulmonary fibrosis

Kang HR, Choi SM

Interstitial lung disease (ILD) is a rare condition characterized by extensive inflammation and fibrosis mainly involving the pulmonary interstitium or alveoli. Usually, patients with ILD clinically present with chronic cough...
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A Case of Severe Pneumocystis Pneumonia in a Thyroid Cancer Patient Receiving Lenvatinib

Jin MH, Kim WG, Kim TY, Kim WB, Shong YK, Jeon MJ

Lenvatinib is a multitargeted tyrosine kinase inhibitor approved for use in patients with iodine-131–refractory thyroid cancer. The common adverse events of lenvatinib include hypertension, proteinuria, fatigue, and diarrhea. To date,...
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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 3. Idiopathic Nonspecific Interstitial Pneumonia

Lee J, Kim YH, Kang JY, Jegal Y, Park SY, on behalf of Korean Interstitial Lung Diseases Study Group

Idiopathic nonspecific interstitial pneumonia (NSIP) is one of the varieties of idiopathic interstitial pneumonias. Diagnosis of idiopathic NSIP can be done via multidisciplinary approach in which the clinical, radiologic, and...
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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 1. Introduction

Park SW, Baek AR, Lee HL, Jeong SW, Yang SH, Kim YH, Chung MP, on behalf of the Korean Interstitial Lung Diseases Study Group

Idiopathic interstitial pneumonia (IIP) is a histologically identifiable pulmonary disease without a known cause that usually infiltrates the lung interstitium. IIP is largely classified into idiopathic pulmonary fibrosis, idiopathic non-specific...
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Lymphocytic interstitial pneumonia in a patient with Sjögren's syndrome

Lee EH, Park JE, Goag EK, Kim YJ, Jung IY, Kim CY, Park YM, Lee JM, Park MS

Lymphocytic interstitial pneumonia (LIP) is a rare benign lymphoproliferative disorder characterized by diffuse infiltration of the pulmonary parenchymal interstitium by polyclonal lymphocytes and plasma cells. LIP has been associated with...
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A Case of Desquamative Interstitial Pneumonia with an Increased Number of Eosinophils in Bronchoalveolar Lavage Fluid

Choi Y, Kim TH, Kang LH, Kim HJ, Jang JH, Shin DH, Jeon D

Here, we present a case of desquamative interstitial pneumonia (DIP) that was initially misdiagnosed as chronic eosinophilic pneumonia due to an increased number of eosinophils in the bronchoalveolar lavage fluid...
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Idiopathic Pleuroparenchymal Fibroelastosis Presenting in Recurrent Pneumothorax: A Case Report

Noh HJ, Seo Y, Huo SM, Kim TJ, Kim HL, Song JS

Idiopathic pleuroparenchymal fibroelastosis (PPFE) is a rare, recently classified entity that consists of pleural and subjacent parenchymal fibrosis predominantly in the upper lungs. In an official American Thoracic Society/European Respiratory...
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Chronic Epstein-Barr virus infection causing both benign and malignant lymphoproliferative disorders

Kwun Y, Hong SJ, Lee JS, Son DH, Seo JJ

The Epstein-Barr virus (EBV) is oncogenic and can transform B cells from a benign to a malignant phenotype. EBV infection is also associated with lymphoid interstitial pneumonia (LIP). Here, we...
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Clinical Significance of Serum Autoantibodies in Idiopathic Interstitial Pneumonia

Kang BH, Park JK, Roh JH, Song JW, Lee CK, Kim M, Jang SJ, Colby TV, Kim DS

Although autoantibodies are routinely screened in patients with idiopathic interstitial pneumonia, there are no reliable data on their clinical usefulness. The aim of this study was to investigate the prognostic...
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Remission of Lymphocytic Interstitial Pneumonia in Sjogren's Syndrome after Autologous Peripheral Blood Stem Cell Transplantation

Choi HN, Choe JY, Kim SH, Kim SK, Ryoo HM, Park SH

Interstitial pneumonia occurs in approximately 25% of patients with primary Sjogren's syndrome. Interstitial pneumonia combined with primary Sjogren's syndrome usually responds well to systemic steroids, and fatal cases are rare....
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Radiologic Approach to the Idiopathic Interstitial Pneumonias

Oh YW

  • KMID: 2082452
  • Korean J Med.
  • 2013 Apr;84(4):489-497.
Idiopathic interstitial pneumonias (IIP), a heterogeneous group of diffuse parenchymal lung diseases, include seven clinicopathologic entities: idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia (NSIP), cryptogenic organizing pneumonia (COP), acute interstitial...
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A Case of Bronchiolitis Interstitial Pneumonitis

Kim MJ, Kim YS, Kim DH, Jun TY, Lee SJ, Kim YJ

  • KMID: 2267916
  • Korean J Med.
  • 2013 Jan;84(1):105-110.
Interstitial lung diseases are diagnosed based on clinical, radiological, and histopathological findings. There are various kinds of interstitial lung diseases involving both the interstitium and bronchioles. Bronchiolitis interstitial pneumonitis (BIP)...
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Two Series of Familial Cases With Unclassified Interstitial Pneumonia With Fibrosis

Lee E, Seo JH, Kim HY, Yu J, Song JW, Park YS, Jang SJ, Do KH, Kwon J, Park SW, Park JH, Hong SJ

Several children presenting with mild symptoms of respiratory tract infection were diagnosed with unclassified interstitial pneumonia with fibrosis. Their clinical and radiological findings were similar to those of acute interstitial...
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