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International Cross-Sectional Survey among Healthcare Professionals on the Management of Cow’s Milk Protein Allergy and Lactose Intolerance in Infants and Children

Madrazo JA, Alrefaee F, Chakrabarty A, Leon JCd, Geng L, Gong S, Heine RG, Järvi A, Ngamphaiboon J, Ong C, Rogacion JM

Purpose: The present international survey among healthcare providers aimed to collect data on theoretical knowledge and clinical practices in the diagnosis and management of cow’s milk protein allergy (CMPA) and...
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Self-reported Non-celiac Gluten Sensitivity in the Korean Population: Demographic and Clinical Characteristics

Cha RR, Kim JH, Koo HS, Jung KW, Min YW, Choi CH, Ryu HS, Kwon YH, Cho DH, Kwon JG, Park KS, Kim HJ

  • KMID: 2528043
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):283-290.
  • doi: 10.5056/jnm21108
Background/Aims Non-celiac gluten sensitivity is characterized by intestinal and extra intestinal symptoms associated with the consumption of gluten- containing food. Since biomarkers for non-celiac gluten sensitivity are lacking, its prevalence is estimated...
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A case of food-induced acute pancreatitis in a child with egg white allergy

Lee Y, Hwang J, Kim SK, Kim MJ, Jeon TY, Kim J, Ahn K, Kim J

Acute pancreatitis (AP) rarely occurs in association with food allergy (FA), and the mechanism is not clearly explored. We herein report a rare case of egg protein-induced AP. A 5-year-old...
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Perilla seed allergy in children: Cosensitization and cross-reactivity with sesame seed

Kim H, Gantulga P, Lee E, Lee J, Lee S, Jeong K

Purpose: Perilla seed (PS) is the most common cause of seed-induced anaphylaxis in Korean children, but the reports on PS allergy, including phenotype and cross-reactivity, are rare. The aim of...
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Additional diagnostic value of component resolved diagnosis in children with kiwifruit allergy

Lee J, Kim H, Jeong K, Jeon SA, Lee S

Purpose: In food allergy, significant component antigens can be assessed by using the microarray. The purpose of this study was to evaluate the diagnostic value of component resolved diagnosis (CRD)...
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Desensitization for the prevention of drug hypersensitivity reactions

Kang SY, Seo J, Kang HR

Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose....
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DRESS (drug reaction with eosinophilia and systemic symptoms) syndrome induced by lamotrigine in a child

Kim HN, Kim SY, Kim KM, Chun YH, Kim HH, Kim JT

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and severe adverse drug reaction characterized by the cutaneous eruption, fever, eosinophilia, and involvement of internal organs. It...
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Expert opinion: The clinical usefulness of skin tests prior to the administration of beta-lactam antibiotics

Kim SR, Kim S, Kim SH, Park JS, Park HJ, Suh DI, Sim DW, Yang MS, Lee JH, Lee HY, Jung JW, Choi M, Kang HR, Drug Allergy Working Group of Korean Academy of Asthma Allergy and Clinical Immunology

An allergy skin test is used to diagnose certain allergies by identifying sensitized allergens. In other words, it is a test for patients who are already sensitized to certain allergens....
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Management of patients with allergy to local anesthetics: two case reports

Arya V, Arora G, Kumar S, Kaur A, Mishra S

Lidocaine is the most commonly used local anesthetic (LA) agent in various dental as well as oral and maxillofacial procedures. Although rare, adverse effects and allergic reactions to lidocaine have...
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Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in liver transplantation

Cho A, Lee JM, Hong K, Han ES, Hong SK, Choi Y, Yi NJ, Lee KW, Suh KS

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare delayed-type hypersensitivity reaction that causes skin abnormalities and mucosal involvement of the entire body. This is a case...
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Clinical Features and Prognostic Factors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Retrospective Study of Data from 88 Patients

Hong JY, Chung EH, Yang NG, Kim JY, Heo NH, Lee SH, Kim JE, Lee SY

  • KMID: 2520798
  • Korean J Dermatol.
  • 2021 Sep;59(8):604-610.
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially fatal acute hypersensitivity reactions that involve the skin and mucous membranes. Because they are relatively rare diseases, it is...
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Prediction of Food Allergens Sensitization Based on History Taking Technique in Young Children

Lee J, Jeong K, Lee E, Lee S

Background: The diagnosis of food allergies needs to be confirmed through an oral food challenge (OFC). However, specific immunoglobulin E (sIgE) concentrations analyzed by serological tests are also helpful in...
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Immunogloboulin E-Mediated Food Sensitization in Children with Celiac Disease: A Single-Center Experience

Cudowska B, Lebensztejn DM

Purpose Celiac disease (CD) is an autoimmune disorder of the small intestine caused by an abnormal immune response to gluten proteins and is often characterized by gastrointestinal symptoms. Food allergy (FA)...
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Diagnosis and Management of Antibiotic Allergies

Kim JH

Drug allergies encompass a spectrum of immune-mediated hypersensitivity reactions with various mechanisms and clinical presentations. β-lactam drugs are common causes of drug allergies. A detailed clinical history as well as...
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Food allergies and food-induced anaphylaxis: role of cofactors

shin M

Food allergies and food-induced anaphylaxis are important health problems. Several cofactors modulating the onset of anaphylaxis have been identified. In the presence of cofactors, allergic reactions may be induced at...
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Diagnosis of Hypersensitivity Pneumonitis: 2020 Clinical Practice Guideline

Park S, Oh YW, Kang EY, Yong HS, Kim C, Lee KY, Hwang SH

Hypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD) characterized by an inhaled inciting antigen that leads to the inflammation of the lung parenchyma and small airway with immunologic reactions....
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A single nonsteroidal anti-inflammatory drugs-induced anaphylaxis to diclofenac confirmed by skin testing

Lee J

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a major culprit of drug-induced hypersensitivity. No reliable diagnostic tests other than a direct challenge are available. Cross-reactivity among NSAIDs that inhibit cyclooxygenase-1 is common....
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Growth in Infants with Cow's Milk Protein Allergy Fed an Amino AcidBased Formula

Vandenplas Y, Dupont C, Eigenmann P, Heine RG, Høst A, Järvi A, Kuitunen M, Mukherjee R, Ribes-Koninckx C, Szajewska H, Berg Av, Zhao ZY, on behalf of the Mosaic Study Investigator Group

Purpose: The present study assessed the role of an amino acid-based formula (AAF) in the growth of infants with cow's milk protein allergy (CMPA). Methods: Non-breastfed, term infants aged 0–6 months...
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Retrospective and Prospective Determination of the Cow's MilkRelated Symptom Score (CoMiSS™) Values in Symptomatic Infants

Kozłowska-Jalowska A, Horvath A, Vandenplas Y, Szajewska H

Purpose: The Cow's Milk-related Symptom Score (CoMiSS™) was developed as an awareness tool for evaluating cow's milk-related symptoms in otherwise healthy children. Using a convenience sample of participants, this cross-sectional...
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Role of Krebs von den Lungen-6 (KL-6) in Assessing Hypersensitivity Pneumonitis

Mostafa AI, Salem AE, Ahmed HAM, Bayoumi AI, Halim RMA, Samie RMA

Background: Hypersensitivity pneumonitis (HP) is an increasingly recognized form of diffuse parenchymal lung disease. Krebs von den Lungen-6 (KL-6) is now classified as a human MUC1 mucin protein, and regenerating...
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