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Effect of Gentamicin Collagen Sponge on Wound Healing: In Vivo Study and Assessment of Its Effectiveness against Nosocomial Bacteria

Lee HM, Park JW, Na YC, Yoon CS, Kim JH, Park JH

Background: Gentamicin collagen sponge (Genta-Coll) reportedly has a hemostatic effect and promotes wound healing. However, it may also interfere with wound healing by causing foreign body reactions. We planned to...
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Hemostats in Spine Surgery: Literature Review and Expert Panel Recommendations

Huec JL, AlEissa S, Bowey A, Debono B, El-Shawarbi A, Fernández-Baillo N, Han K, Martin-Benlloch A, Pflugmacher R, Sabatier P, Vanni D, Walker I, Warren T, Litrico S

Bleeding in spine surgery is a common occurrence but when bleeding is uncontrolled the consequences can be severe due to the potential for spinal cord compression and damage to the...
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Clinical application of a new hemostatic material using mussel-inspired catecholamine hemostat: A pilot study

Park YM, Seo HI, Kim JH, Yoon SP, Lee H, Lee MS

Backgrounds/Aims: This study aimed to evaluate clinical application of InnoSEAL Plus (a mussel-inspired catecholamine hemostat) as a new hemostatic material for humans. Methods: Patients treated with topical hemostatic patches after liver...
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In vivo study for the hemostatic efficacy and foreign body reaction of a new powder-type polysaccharide hemostatic agent

Byun Y, Kim EJ, Lee A, Suh YA, Sohn HJ, Lee JM, Kang JS, Choi YJ, Han Y, Kim H, Kwon W, Jang JY

Purpose: Various hemostatic agents have been introduced in therapy as postoperative bleeding is a poor prognostic factor for postoperative outcomes. These products can be divided into those that directly promote...
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A multicenter, prospective, randomized clinical trial of marine mussel-inspired adhesive hemostatic materials, InnoSEAL Plus

Choi GS, Kim SH, Seo HI, Ryu JH, Yun SP, Koh MY, Lee MS, Lee H, Kim JH

Purpose: InnoSEAL Plus is an adhesive, coagulant-free hemostatic material that mimics the adhesion mechanism of marine mussels. This study reports on the safety and efficacy of InnoSEAL Plus for patients...
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Management of an Inappropriately Treated Case of Auricular Hematoma

Kim Y, Choi JW, Park YH

Othematoma is a condition in which blood collects beneath the perichondral layer of the pinna. Recurrent auricular hematoma can be a challenging medical problem, with complications resulting in ear deformity,...
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Wound healing effect of regenerated oxidized cellulose versus fibrin sealant patch: An in vivo study

Yoon HS, Na YC, Choi KH, Huh WH, Kim JM

BACKGROUND: Topical hemostatic agents are used when ligation, electrocauterization, or other conventional hemostatic methods are impractical. Because a hemostatic agent is a foreign body, it can cause foreign body reactions,...
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Comparison of hemostatic efficacy and cytotoxicity of three ferric subsulfate- and chitosan-based styptics in different formulations using a rat tail bleeding model

Byun JY, Lee S, Lee JI, Yoon HY

This study was conducted to compare the hemostatic efficacy of three ferric subsulfate- and chitosan-based styptics as a powder and a gel containing ferric subsulfate and chitosan (FSC-PO and FSC-G,...
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Chitosan Pad, Cellulose Membrane, or Gelatin Sponge for Peridural Bleeding: An Efficacy Study on a Lumbar Laminectomized Rat Model

Sae-Jung S, Apiwatanakul P

STUDY DESIGN: Experimental study in an animal model. PURPOSE: This study aims to evaluate the hemostatic properties of four common hemostatic materials including the chitosan clot pad, absorbable gelatin sponge, cellulose...
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Postoperative Spinal Epidural Hematoma: The Danger Caused by the Misuse of Thrombin-Containing Local Hemostatics

Ahn DK, Shin WS, Kim GW, Koo KH

STUDY DESIGN: Retrospective case-control study. PURPOSE: To examine the hypothesis that the misuse of thrombin-containing local hemostatics (TCLH) increases the risk of postoperative spinal epidural hematoma (POSEH). OVERVIEW OF LITERATURE: Many studies...
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Efficacy of Oxidized Regenerated Cellulose, SurgiGuard®, in Porcine Surgery

Kim SH, Kim SH, Yoon HS, Kim HK, Kim KS

PURPOSE: Adequate hemostasis is important for postoperative outcomes of abdominal surgery. This study evaluated the hemostatic effects and accompanying histopathological changes of a novel oxidized regenerated cellulose, SurgiGuard®, during abdominal...
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Biologic response of local hemostatic agents used in endodontic microsurgery

Jang Y, Kim H, Roh BD, Kim E

  • KMID: 2316876
  • Restor Dent Endod.
  • 2014 May;39(2):79-88.
Appropriate use of local hemostatic agent is one of the important factors on the prognosis of endodontic microsurgery. However, most investigations to date focus on the hemostatic efficacy of the...
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Comparison of the Wound Healing Effect of Cellulose and Gelatin: An In Vivo Study

Kang BS, Na YC, Jin YW

BACKGROUND: Many topical hemostatics are widely applied for bleeding control. They can be classified into two categories according to their mechanism of action on the clotting cascade in a biologically...
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Hemostatic Efficacy of Topical Application of Cold Hydrogen Peroxide in Adenoidectomy

Chang HJ, Baek SH, Choi CY, Kang SN, Park JB, Lee WY, Kim CA

  • KMID: 2276065
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Nov;46(11):946-949.
BACKGROUND AND OBJECTIVES: Adenoidectomy is one of the most common procedures in the field of otolaryngology, and various hemostatic agents and techniques have been used for stanching the wound of...
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