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Valproic Acid Exposure during Early Postnatal Gliogenesis Leads to Autistic-like Behaviors in Rats

Mony TJ, Lee JW, Dreyfus C, DiCicco-Bloom E, Lee HJ

OBJECTIVE: We reported that postnatal exposure of rats to valproic acid (VPA) stimulated proliferation of glial precursors during cortical gliogenesis. However, there are no reports whether enhanced postnatal gliogenesis affects...
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Adult Neurogenesis and Gliogenesis: Possible Mechanisms for Neurorestoration

Rusznák Z, Henskens W, Schofield , Kim WS, Fu Y

The subgranular zone (SGZ) and subventricular zone (SVZ) are developmental remnants of the germinal regions of the brain, hence they retain the ability to generate neuronal progenitor cells in adult...
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Roles of mTOR Signaling in Brain Development

Lee DY

mTOR is a serine/threonine kinase composed of multiple protein components. Intracellular signaling of mTOR complexes is involved in many of physiological functions including cell survival, proliferation and differentiation through the...
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Bis Is Involved in Glial Differentiation of P19 Cells Induced by Retinoic Acid

Yoon JS, Lee MY, Lee JS, Park CS, Youn HJ, Lee JH

Previous observations suggest that Bis, a Bcl-2-binding protein, may play a role the neuronal and glial differentiation in vivo. To examine this further, we investigated Bis expression during the in...
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Transplantation of Human Umbilical Cord Blood Improves Neurological Outcomes in the Rats after Traumatic Spinal Cord Injury

Ha Y, Yoon SH, Park HC, Kim KN, Yoon DH, Cho YE

  • KMID: 2339799
  • J Korean Neurosurg Soc.
  • 2004 Mar;35(3):302-308.
OBJECTIVE: Recent advances in stem cell biology make it possible to induce the regeneration of injured axons and to replace lost cells in the injured spinal cord. It has been...
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