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Copy Number Variation Burden on Asthma Subgenome in Normal Cohorts Identifies Susceptibility Markers

Vishweswaraiah S, Veerappa A, Mahesh PA, Jahromi SR, Ramachandra NB

PURPOSE: Asthma is a complex disease caused by interplay of genes and environment on the genome of an individual. Copy number variations (CNVs) are more common compared to the other...
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Quantitative Analysis of Cancer-associated Gene Methylation Connected to Risk Factors in Korean Colorectal Cancer Patients

Kang HJ, Kim EJ, Kim BG, You CH, Lee SY, Kim DI, Hong YS

OBJECTIVES: The purpose of this paper was to elucidate the potential methylation levels of adjacent normal and cancer tissues by comparing them with normal colorectal tissues, and to describe the...
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Genetic Markers for Idiopathic Scoliosis in Arab Population: A Pilot Study

Al-Omran A, Sadat-Ali , Al-Othman

STUDY DESIGN: Cross-sectional screening. PURPOSE: This study was conducted to determine if there is any association of the three microsatellite markers on chromosome 19p 13.3 in unrelated Saudi Arabian girls who...
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Ultrasonographic, cytologic and genetic diagnosis of thyroid cancers

Kang HC

  • KMID: 2257143
  • Korean J Med.
  • 2009 Nov;77(5):543-551.
Thyroid nodules are very common in adults, but only small fraction of them are malignant. The primary aim in investigating a thyroid nodule is to exclude the possibility of malignancy,...
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Risk Assessment and Pharmacogenetics in Molecular and Genomic Epidemiology

Park SK, Choi JY

In this article, we reviewed the literature on risk assessment (RA) models with and without molecular genomic markers and the current utility of the markers in the pharmacogenetic field. Epidemiological...
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Heterozygosities of 735 microsatellite markers and background linkage disequilibrium in the Korean population

Lee KA, Kim JW

  • KMID: 1115944
  • Exp Mol Med.
  • 2006 Dec;38(6):662-667.
Suitability of a specific population for linkage disequilibrium mapping studies of complex traits may be assessed by investigating the background linkage disequilibrium (BLD). We are unaware of studies for quantifying...
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Marker Chromosomes in Korean Patients: Incidence, Identification and Diagnostic Approach

Woo HY, Cho HJ, Kong SY, Kim HJ, Jeon HB, Kim EC, Park H, Kim YJ, Kim SH

The identification of marker chromosomes is important for genetic counseling. However, the origin or composition can rarely be defined with conventional cytogenetic technique alone. In this study, we investigated the...
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