- Differentiation induction of dendritic cell phenotypes from human leukemic cell lines
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Lee DH, Park JS, Eo WK, Kim WM, Kang K
- KMID: 1606842
- Korean J Physiol Pharmacol.
- 2001 Feb;5(1):79-86.
Recent clinical studies have shown that a high proportion of patients with acute promyelocytic leukemia (APL) achieve complete remission after treatment with all-trans retinoic acid (ATRA). However, most patients who receive continuous treatment... -
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- Prognostic Significance of FLT3 Internal Tandem Duplication in Acute Myeloid Leukemia with Normal Karyotype
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Lee JY, Joo YD, Oh SH, Shin JH, Kim HR, Lee SM, Lee JN
- KMID: 2252151
- Korean J Hematol.
- 2009 Jun;44(2):74-81.
- doi: 10.5045/kjh.2009.44.2.74
BACKGROUND: Activating mutations of the fms-like tyrosine kinase 3 gene (FLT3) by internal tandem duplication (ITD) in the juxtamembrane region are found in 20~30% of the adults with acute myeloid... -
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- Prevalence of FLT3 Internal Tandem Duplication in Adult Acute Myelogenous Leukemia
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Lee JN, Kim HR, Shin JH, Joo YD
- KMID: 1781490
- Korean J Lab Med.
- 2007 Aug;27(4):237-243.
- doi: 10.3343/kjlm.2007.27.4.237
BACKGROUND: fms-like tyrosine kinase (FLT3), a member of the class III receptor tyrosine kinases, regulates the proliferation and differentiation of hematopoietic stem cells. An internal tandem duplication of the... -
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- Annual Report on External Quality Assessment in Diagnostic Genetics in Korea (2009)
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Kim SH, Ki CS, Kim S, Kwon MJ, Kim JW, Park SS, Kim JS, Lee YK, Kong SY, Ki SJ, Han SH, Seo EJ, CHo HC, Kim EJ, Kim PW
- KMID: 2200555
- J Lab Med Qual Assur.
- 2010 Jun;32(1):147-170.
BACKGROUND: The quality control for genetic tests would be of great importance as the test volume and clinical demands increase dramatically. Diagnostic genetics subcommittee of KSQACL performed two trials for... -
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- Annual Report on the External Quality Assessment of Diagnostic Genetics in Korea (2015)
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Kim HY, Park CH, Lee SJ, Cho SI, Seong MW, Park SS, Kim SH, Diagnostic Genetics Subcommittee, Korean Association of External Quality Assessment Service
- KMID: 2162120
- J Lab Med Qual Assur.
- 2016 Mar;38(1):22-42.
- doi: 10.15263/jlmqa.2016.38.1.22
The Diagnostic Genetics Subcommittee of Korean Association of External Quality Assessment Service conducted two trials in 2015 based on cytogenetics and molecular genetics surveys. A total of 43 laboratories participated... -
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- Annual Report on the External Quality Assessment Scheme for Diagnostic Genetics in Korea (2014)
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Park CH, Shin SY, Park H, Cho SI, Seong MW, Park SS, Kim SH, Diagnostic Genetics Subcommittee, The Korean Association of External Quality Assessment Service
- KMID: 2200370
- J Lab Med Qual Assur.
- 2015 Jun;37(2):64-83.
- doi: 10.15263/jlmqa.2015.37.2.64
Quality control for genetic tests has become more important as testing volume and clinical demands have increased dramatically. The diagnostic genetics subcommittee of Korean Association of External Quality Assessment Service... -
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- Correlation of NPM1 Type A Mutation Burden With Clinical Status and Outcomes in Acute Myeloid Leukemia Patients With Mutated NPM1 Type A
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Jo SY, Park SH, Kim IS, Yi J, Kim HH, Chang CL, Lee EY, Cho YU, Jang S, Park CJ, Chi HS
- KMID: 2373568
- Ann Lab Med.
- 2016 Sep;36(5):399-404.
- doi: 10.3343/alm.2016.36.5.399
BACKGROUND: Nucleophosmin gene (NPM1) mutation may be a good molecular marker for assessing the clinical status and predicting the outcomes in AML patients. We evaluated the applicability of NPM1 type... -
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- Low Frequency and Variability of FLT3 Mutations in Korean Patients with Acute Myeloid Leukemia
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Bang SM, Ahn JY, Park J, Park SH, Park J, Cho EK, Shin DB, Lee JH, Yoo SJ, Jeon IS, Kim YK, Kim HJ, Kim HN, Lee IK, Kang HJ, Shin HY, Ahn HS
- KMID: 1783069
- J Korean Med Sci.
- 2008 Oct;23(5):833-837.
- doi: 10.3346/jkms.2008.23.5.833
FLT3 mutations are common genetic changes, and are reported to have prognostic significance in acute myeloid leukemia (AML). The FLT3 internal tandem duplication (ITD) and the D835 activating mutation in... -
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