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Analysis of Cooperation Project for Early Diagnosis of Leprosy from 2009 to 2018

Park JM, Kim HJ, Kim JP

  • KMID: 2526763
  • Korean J Dermatol.
  • 2022 Feb;60(2):75-81.
Background: Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae. As leprosy has a long disease course, various dermatoses must be considered in the differential diagnosis. Objective: In Korea, due...
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The optimal anti-phospholipase A2 receptor cutoff for the diagnosis of idiopathic membranous nephropathy: a single-center retrospective study

Li C, Li P, Guo W, Chen L, Li J, Wang R, Chen B

Background/Aims: Anti-phospholipase A2 receptor (PLA2R) autoantibody is the main biomarker of idiopathic membranous nephropathy (IMN). We aimed to find a new cutoff value of anti-PLA2R for patients with IMN and...
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Can reactogenicity predict immunogenicity after COVID-19 vaccination?

Hwang YH, Song KH, Choi Y, Go S, Choi SJ, Jung J, Kang CK, Choe PG, Kim NJ, Park WB, Oh Md

Background/Aims: This study aimed to assess the association between local and systemic reactogenicity and humoral immunogenicity after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. Methods: Adverse events were prospectively evaluated...
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Safety and Effectiveness of Cytomegalovirus Specific Antigen Induced Interferon-Gamma ELISPOT/ELISA: A Systematic Review

Choi W, Hahn J, Lee W, Shin C

Background: This study evaluated the safety and effectiveness of the cytomegalovirus (CMV) Specific Antigen Induced Interferon-Gamma ELISPOT (enzyme-linked immunosorbent spot)/ELISA (enzyme-linked immunosorbent assay) procedure in predicting the risk of CMV...
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Association Between Elevated Serum Macrophage Colony-Stimulating Factor Levels and Clinicopathological Features in B-cell Lymphoma Patients

Choi HW, So HJ, Kim H, Oh Ac, Lee JK, Hong YJ, Hong SI, Chang YH

Background: Macrophage colony-stimulating factor (M-CSF) regulates the proliferation and supports the viability of monocytes, macrophages, and their bone marrow progenitors. M-CSF is found in high concentrations in the serum of...
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Evaluation of serum immunoglobulin G4 concentrations in canine pancreatitis

Moon MY, Kim J, Kim HJ

The goal of this study was to measure immunoglobulin G4 (IgG4) concentrations and to evaluate the significance of these values in the management of canine pancreatitis. The medical records of...
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Diagnostic model for pancreatic cancer using a multi-biomarker panel

Choi YJ, Yoon W, Lee A, Han Y, Byun Y, Kang JS, Kim H, Kwon W, Suh YA, Kim Y, Lee S, Namkung J, Han S, Choi Y, Heo JS, Park JO, Park JK, Kim SC, Kang CM, Lee WJ, Park T, Jang JY

Purpose: Diagnostic biomarkers of pancreatic ductal adenocarcinoma (PDAC) have been used for early detection to reduce its dismal survival rate. However, clinically feasible biomarkers are still rare. Therefore, in this...
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Comparative analysis of serological tests and fecal detection in the diagnosis of Mycobacterium avium subspecies paratuberculosis infection

Park HT, Ha S, Park HE, Shim S, Hur TY, Yoo HS

Abstract: Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a chronic, wasting infectious disease in ruminants that causes enormous economic losses to the dairy and beef cattle...
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Inhibitory effect of pomegranate extract powder on periodontitis in rat

Kim JH, Lee KH, Sung SJ, Kang KM, Lim YK, Kook JK, Lee WP, Kim BO, Yu SJ

This study aimed to investigate the effect of pomegranate extract (PE) on the progression of periodontal disease in an experimental rat model of periodontitis. Periodontitis was induced in rats by...
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A Comparison of Accuracy between IMMULITE2000® and GENEDIA® for Helicobacter pylori Infection

Lim SH, Kim N, Kim SE, Baik GH, Lee JY, Park KS, Shin JE, Song HJ, Myung DS, Choi SC, Kim HJ

Background/Aims: In serological tests for Helicobacter pylori (H. pylori), an enzyme-linked immunosorbent assay (GENEDIA®) and a solid-phase, two-step chemiluminescent enzyme immunoassay (IMMULITE®), which are easy to perform, inexpensive, and widely...
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Immunological measurement of aspartate/alanine aminotransferase in predicting liver fibrosis and inflammation

Kim HJ, Kim SY, Shin SP, Yang YJ, Bang CS, Baik GH, Kim DJ, Ham YL, Choi EY, Suk KT

Background/Aims: Enzymatic analysis of aspartate/alanine aminotransferase (AST/ALT) does not exactly represent the progression of liver fibrosis or inflammation. Immunoassay for AST (cytoplasmic [c] AST/mitochondrial [m] AST) and ALT (ALT1/ALT2) has...
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Correlation between Salivary Mucin Concentration and Viscosity -An Exploratory Study in Healthy People

Kim S, Jeon H, Choi JS, Oh BM, Seo HG, Yoo B, Han TR

Objective: To analyze the rheological and biochemical properties of saliva in healthy adults. Methods: The subjects were seven healthy young adults (20-39 years). The whole saliva was collected by the spitting...
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Age-specific variations in hematological and biochemical parameters in middle- and large-sized of dogs

Lee SH, Kim JW, Lee BC, Oh HJ

Aging triggers cellular and molecular alterations, including genomic instability and organ dysfunction, which increases the risk of disease in mammals. Recently, due to the markedly growing number of aging dogs...
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Detection of Anti-Extractable Nuclear Antigens in Patients with Systemic Rheumatic Disease via Fluorescence Enzyme Immunoassay and Its Clinical Utility

Oh J, Park Y, Lee KA, Kim HS

PURPOSE: Testing for autoantibodies to extractable nuclear antigens (ENAs) plays an important role in the diagnosis and management of systemic rheumatic disease. Currently, no gold standard tests are available for...
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The correlation between serum vascular endothelial growth factor (VEGF) and tumor VEGF receptor 3 in colorectal cancer

Goulart A, Ferreira C, Rodrigues , Coimbra B, Sousa N, Leão P

PURPOSE: Despite plasma biomarkers offering a number of advantages over tissue-based markers, the relationship between serum vascular endothelial growth factor (VEGF) and VEGF receptor (VEGF-R) tumor expression in colorectal cancer...
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The usefulness of fecal calprotectin in assessing inflammatory bowel disease activity

Lee YW, Lee KM, Lee JM, Chung YY, Kim DB, Kim YJ, Chung WC, Paik CN

BACKGROUND/AIMS: Fecal calprotectin (FC) is known to correlate with disease activity and can be used as a predictor for relapse or treatment response in inflammatory bowel disease (IBD). We evaluated...
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Development of a HA1-specific enzyme-linked immunosorbent assay against pandemic influenza virus A H1N1

Shim DH, Kim MJ, Cha HR, Park ES, Kim AR, Park JH, Park HC, Song D, Lee JM

PURPOSE: Enzyme-linked immunosorbent assay (ELISA) has been used in the diverse field to evaluate influenza virus infection; for the surveillance, diagnosis, efficacy evaluation, and development of the vaccine. The aim...
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Enzyme-linked immunosorbent assay for detecting anti-pertussis toxin antibody in mouse

Choi GS, Huh DH, Han SB, Ahn DH, Kang KR, Kim JA, Choi BM, Kim HR, Kang JH

PURPOSE: Although the DTaP and Tdap vaccines used to prevent pertussis have been used for a long time, there is no standard method for measuring pertussis antigens. Therefore, this preliminary...
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Development and implementation of standardized method for detecting immunogenicity of acellular pertussis vaccines in Korea

Park C, Huh DH, Han SB, Choi GS, Kang KR, Kim JA, Kang JH

PURPOSE: There is no standard method for confirming the immunogenicity of acellular pertussis vaccines. We tried to develop a local standard method for evaluating the immunogenicity of the three-component of...
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Expression and serological application of recombinant epitope-repeat protein carrying an immunodominant epitope of Newcastle disease virus nucleoprotein

Gaikwad SS, Lee HJ, Kim JY, Choi KS

PURPOSE: The aim of the present study was to develop a serodiagnostic test for differentiation infected from vaccinated animal (DIVA) strategy accompanying the marker vaccine lacking an immunodominant epitope (IDE)...
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