- Sirtinol Supresses Trophozoites Proliferation and Encystation of Acanthamoeba via Inhibition of Sirtuin Family Protein
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Joo SY, Aung JM, Shin M, Moon EK, Kong HH, Goo YK, Chung DI, Hong Y
- KMID: 2526668
- Korean J Parasitol.
- 2022 Feb;60(1):1-6.
- doi: 10.3347/kjp.2022.60.1.1
The encystation of Acanthamoeba leads to the development of metabolically inactive and dormant cysts from vegetative trophozoites under unfavorable conditions. These cysts are highly resistant to anti-Acanthamoeba drugs and biocides.... -
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- Transcriptomic Features of Echinococcus granulosus Protoscolex during the Encystation Process
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Fan J, Wu H, Li K, Liu X, Tan Q, Cao W, Liang B, Ye B
- KMID: 2505096
- Korean J Parasitol.
- 2020 Jun;58(3):287-299.
- doi: 10.3347/kjp.2020.58.3.287
Cystic echinococcosis (CE) is a zoonotic infection caused by Echinococcus granulosus larvae. It seriously affects the development of animal husbandry and endangers human health. Due to a poor understanding of... -
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- Efficient Liquid Media for Encystation of Pathogenic Free-Living Amoebae
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Sohn HJ, Kang H, Seo GE, Kim JH, Jung SY, Shin HJ
- KMID: 2387178
- Korean J Parasitol.
- 2017 Jun;55(3):233-238.
- doi: 10.3347/kjp.2017.55.3.233
Pathogenic Naegleria fowleri, Acanthamoeba castellanii, and Acanthamoeba polyphaga, are distributed worldwide. They are causative agents of primary amoebic meningoencephalitis or acanthamoebic keratitis in humans, respectively. Trophozoites encyst in unfavorable environments,... -
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- DNA Methylation of Gene Expression in Acanthamoeba castellanii Encystation
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Moon EK, Hong Y, Lee HA, Quan FS, Kong HH
- KMID: 2379412
- Korean J Parasitol.
- 2017 Apr;55(2):115-120.
- doi: 10.3347/kjp.2017.55.2.115
Encystation mediating cyst specific cysteine proteinase (CSCP) of Acanthamoeba castellanii is expressed remarkably during encystation. However, the molecular mechanism involved in the regulation of CSCP gene expression remains unclear. In... -
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- Identification and Characterization of Protein Arginine Methyltransferase 1 in Acanthamoeba castellanii
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Moon EK, Kong HH, Hong Y, Lee HA, Quan FS
- KMID: 2379411
- Korean J Parasitol.
- 2017 Apr;55(2):109-114.
- doi: 10.3347/kjp.2017.55.2.109
Protein arginine methyltransferase (PRMT) is an important epigenetic regulator in eukaryotic cells. During encystation, an essential process for Acanthamoeba survival, the expression of a lot of genes involved in the... -
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- Identification of Protein Arginine Methyltransferase 5 as a Regulator for Encystation of Acanthamoeba
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Moon EK, Hong Y, Chung DI, Goo YK, Kong HH
- KMID: 2164009
- Korean J Parasitol.
- 2016 Apr;54(2):133-138.
- doi: 10.3347/kjp.2016.54.2.133
Encystation is an essential process for Acanthamoeba survival under nutrient-limiting conditions and exposure to drugs. The expression of several genes has been observed to increase or decrease during encystation. Epigenetic... -
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- Down-Regulation of Cellulose Synthase Inhibits the Formation of Endocysts in Acanthamoeba
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Moon EK, Hong Y, Chung DI, Goo YK, Kong HH
- KMID: 1792159
- Korean J Parasitol.
- 2014 Apr;52(2):131-135.
Acanthamoeba cysts are resistant to unfavorable physiological conditions and various disinfectants. Acanthamoeba cysts have 2 walls containing various sugar moieties, and in particular, one third of the inner wall is... -
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- Identification of Atg8 Isoform in Encysting Acanthamoeba
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Moon EK, Hong Y, Chung DI, Kong HH
- KMID: 1792139
- Korean J Parasitol.
- 2013 Oct;51(5):497-502.
Autophagy-related protein 8 (Atg8) is an essential component of autophagy formation and encystment of cyst-forming parasites, and some protozoa, such as, Acanthamoeba, Entamoeba, and Dictyostelium, have been reported to possess... -
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- Short-Cut Pathway to Synthesize Cellulose of Encysting Acanthamoeba
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Moon EK, Kong HH
- KMID: 1792132
- Korean J Parasitol.
- 2012 Dec;50(4):361-364.
The mature cyst of Acanthamoeba is highly resistant to various antibiotics and therapeutic agents. Cyst wall of Acanthamoeba are composed of cellulose, acid-resistant proteins, lipids, and unidentified materials. Because cellulose... -
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- Microarray Analysis of Differentially Expressed Genes between Cysts and Trophozoites of Acanthamoeba castellanii
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Moon EK, Xuan YH, Chung DI, Hong Y, Kong HH
- KMID: 1715738
- Korean J Parasitol.
- 2011 Dec;49(4):341-347.
- doi: 10.3347/kjp.2011.49.4.341
Acanthamoeba infection is difficult to treat because of the resistance property of Acanthamoeba cyst against the host immune system, diverse antibiotics, and therapeutic agents. To identify encystation mediating factors of... -
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- Atg3-Mediated Lipidation of Atg8 Is Involved in Encystation of Acanthamoeba
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Moon EK, Chung DI, Hong Y, Kong HH
- KMID: 1090608
- Korean J Parasitol.
- 2011 Jun;49(2):103-108.
- doi: 10.3347/kjp.2011.49.2.103
Autophagy is a catabolic process involved in the degradation of a cell's own components for cell growth, development, homeostasis, and the recycling of cellular products. Autophagosome is an essential component... -
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- Construction of EST Database for Comparative Gene Studies of Acanthamoeba
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Moon EK, Kim JO, Xuan YH, Yun YS, Kang SW, Lee YS, Ahn TI, Hong YC, Chung DI, Kong HH
- KMID: 1720618
- Korean J Parasitol.
- 2009 Jun;47(2):103-107.
- doi: 10.3347/kjp.2009.47.2.103
The genus Acanthamoeba can cause severe infections such as granulomatous amebic encephalitis and amebic keratitis in humans. However, little genomic information of Acanthamoeba has been reported. Here, we constructed Acanthamoeba... -
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- Differentially expressed genes of Acanthamoeba castellanii during encystation
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Moon EK, Chung DI, Hong YC, Kong HH
- KMID: 1089949
- Korean J Parasitol.
- 2007 Dec;45(4):283-285.
- doi: 10.3347/kjp.2007.45.4.283
To examine the expressed gene profile during encystation of Acanthamoeba castellanii Castellani, we used differentially expressed gene (DGE) screening by RT-PCR with 20 sets of random primers. From this analysis,... -
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- In vivo determination of the gap2 gene promoter activity in Giardia lamblia
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Yang HW, Kim J, Yong TS, Park SJ
- KMID: 1091832
- Korean J Parasitol.
- 2006 Mar;44(1):21-26.
- doi: 10.3347/kjp.2006.44.1.21
A shuttle vector for Escherichia coli and Giardia lamblia was modified to produce a reporter plasmid, which monitors the expression of prescribed gene in G. lamblia by measuring its luciferase... -
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