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The Impact of Masticatory Function on Cognitive Impairment in Older Patients: A Population-Based Matched Case-Control Study

Ko KA, Park JY, Lee JS, Ye BS, Jung UW, Choi SH, Cha JK

Purpose: The aim of this study was to investigate the association between the changes in masticatory function and cognitive impairment by analyzing longitudinal data of older Korean patients. Materials and Methods:...
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Factors Affecting Pressure Ulcer among Inpatients in Long Term Care Facilities: Adults with Cognitive Impairment

Do UH, Park M, Kim SH, Moon KJ

Purpose: The aim of this study was to identify factors affecting pressure ulcers among cognitive impairment inpatients with long term care facilities. Methods: In this secondary data analysis of the...
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Accuracy of Machine Learning Using the Montreal Cognitive Assessment for the Diagnosis of Cognitive Impairment in Parkinson’s Disease

Jeon J, Kim K, Baek K, Chung SJ, Yoon J, Kim YJ

Objective The Montreal Cognitive Assessment (MoCA) is recommended for assessing general cognition in Parkinson’s disease (PD). Several cutoffs of MoCA scores for diagnosing PD with cognitive impairment (PD-CI) have been...
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A Single Baseline Amyloid Positron Emission Tomography Could Be Sufficient for Predicting Alzheimer’s Disease Conversion in Mild Cognitive Impairment

Choo IH, Chong A, Chung JY, Ha JM, Choi YY, Kim H

Objective Baseline amyloid burden in mild cognitive impairment (MCI) has been linked to conversion to Alzheimer’s disease (AD), but the comparison of baseline and longitudinal changes in amyloid burden for...
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The Experience of Chemotherapy Related Cognitive Impairment in Patients with Cancer

Oh PJ, Kim JH

Purpose: This study was conducted to explore the experiences of adult cancer patients living with Chemotherapy-Related Cognitive Impairment (CRCI). Methods: Data were collected by using in-depth and audio-recorded interviews with...
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18F-THK5351 PET Positivity and Longitudinal Changes in Cognitive Function in β-Amyloid-Negative Amnestic Mild Cognitive Impairment

Chun MY, Lee J, Jeong JH, Roh JH, Oh SJ, Oh M, Oh JS, Kim JS, Moon SH, Woo Sy, Kim YJ, Choe YS, Kim HJ, Na DL, Jang H, Seo SW

Purpose: Neuroinflammation is considered an important pathway associated with several diseases that result in cognitive decline. 18F-THK5351 positron emission tomography (PET) signals might indicate the presence of neuroinflammation, as well...
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A Systematic Review on Cognitive Effects of Electroconvulsive Therapy in Asian Patients

Ong Y, Chan LG

Objective: Electroconvulsive therapy (ECT) is the most efficacious treatment for many major mental illnesses but is limited by cognitive side effects. However, research on the pattern and severity of ECT-related...
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Baseline Clinical and Biomarker Characteristics of Biobank Innovations for Chronic Cerebrovascular Disease With Alzheimer’s Disease Study: BICWALZS

Roh HW, Kim NR, Lee Dg, Cheong JY, Seo SW, Choi SH, Kim EJ, Cho SH, Kim BC, Kim SY, Kim EY, Chang J, Lee SY, Yoon D, Choi JW, An YS, Kang HY, Shin H, Park B, Son SJ, Hong CH

Objective We aimed to present the study design and baseline cross-sectional participant characteristics of biobank innovations for chronic cerebrovascular disease with Alzheimer’s disease study (BICWALZS) participants. Methods A total of 1,013...
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Association Between Body Mass Index and Cognitive Function in Mild Cognitive Impairment Regardless of APOE ε4 Status

Mun YS, Park HK, Kim J, Yeom J, Kim GH, Chun MY, Lee HA, Yoon SJ, Park KW, Kim EJ, Yoon B, Jang JW, Hong JY, Choi SH, Jeong JH

Background and Purpose: In this study we aimed to find the association between neuropsychological performance and body mass index (BMI) in patients with mild cognitive impairment (MCI). In addition, we...
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A Comparison Between the Performances of Verbal and Nonverbal Fluency Tests in Discriminating Between Mild Cognitive Impairments and Alzheimer’s Disease Patients and Their Brain Morphological Correlates

Kwak S, Shin SA, Ko H, Kim H, Oh DJ, Youn JH, Lee JY, Kim YK

Background and Purpose: Verbal and nonverbal fluency tests are the conventional methods for examining executive function in the elderly population. However, differences in impairments result in fluency tests in patients...
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Prediction of Cognitive Progression in Individuals with Mild Cognitive Impairment Using Radiomics as an Improvement of the ATN System: A Five-Year Follow-Up Study

Song R, Wu X, Liu H, Guo D, Tang L, Zhang W, Feng J, Li C

Objective: To improve the N biomarker in the amyloid/tau/neurodegeneration system by radiomics and study its value for predicting cognitive progression in individuals with mild cognitive impairment (MCI). Materials and Methods: A...
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Constipation is Associated With Mild Cognitive Impairment in Patients With de novo Parkinson’s Disease

Kang SH, Lee J, Koh SB

Objective The association between gastrointestinal (GI) symptoms and cognitive profile in patients with Parkinson’s disease (PD) at diagnosis remains unclear, although GI symptoms and cognitive impairment are highly prevalent in...
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Decreased Cortical Thickness and Local Gyrification in Individuals with Subjective Cognitive Impairment

Youn H, Choi M, Lee S, Kim D, Suh S, Han CE, Jeong HG

Objective: Subjective cognitive impairment (SCI) is associated with future cognitive decline. This study aimed to compare cortical thickness and local gyrification index (LGI) between individuals with SCI and normal control...
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Amyloid Burden in Alzheimer's Disease Patients Is Associated with Alterations in Circadian Rhythm

Kang J, Choi HJ, Isaacs GD, Sung W, Kim HJ

Background and Purpose: In this study we evaluated the relationship between amyloid-beta (Aβ) deposition and 3 aspects of sleep quality in a group of clinically diagnosed Alzheimer's disease (AD) patients. Methods:...
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Changes in Speech Range Profile Are Associated with Cognitive Impairment

Stefano AD, Giovanni PD, Kulamarva G, Fonzo FD, Massaro T, Contini A, Dispenza F, Cazzato C

Background and Purpose: The aim of this study was to describe the variations in the speech range profile (SRP) of patients affected by cognitive decline. Methods: We collected the data of...
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Comparison of RCF Scoring System to Clinical Decision for the Rey Complex Figure Using Machine-Learning Algorithm

Simfukwe C, An SS, Youn YC

Background and Purpose: Interpreting the Rey complex figure (RCF) requires a standard RCF scoring system and clinical decision by clinicians. The interpretation of RCF using clinical decision by clinicians might...
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Effect of Lifetime Cognitive Reserve on Functional Connectivity in the Default Mode Network at the Predementia Stage

Woo SK, Kang JM, Kim N, Lee SY, Kim S, Kim DJ, Kang CK, Lee JY, Cho SJ

Objective: Cognitive reserve (CR) protects against cognitive decline by utilizing functional connectivity (FC) in the brain, such as the default mode network (DMN). We studied whether CR in individuals with...
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A Comparison of the Performance between the 60- and 120-Second Conditions of the Korean-Color Word Stroop Test: Color Reading (K-CWST: CR)

Lee SH, Kang Y, Song M, Kim GH, Jeong JH

Background and Purpose: The Korean-Color Word Stroop Test: Color Reading (K-CWST: CR) included in the Seoul Neuropsychological Screening Battery, 2nd Edition (SNSB-II) examines inhibitory control deficit. It provides normative data for...
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A Comparison of Speech Features between Mild Cognitive Impairment and Healthy Aging Groups

Kim KW, Na SH, Chung YC, Shin BS

Background and Purpose: Language dysfunction is a symptom common to patients with Alzheimer's disease (AD). Speech feature analysis may be a patient-friendly screening test for early-stage AD. We aimed to...
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Assessment of Mild Cognitive Impairment in Elderly Subjects Using a Fully Automated Brain Segmentation Software

Kwon C, Kang KM, Byun MS, Yi D, Song H, Lee JY, Hwang I, Yoo RE, Yun TJ, Choi SH, Kim Jh, Sohn CH, Lee DY, for the KBASE Research Group

Purpose: Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Brain atrophy in this disease spectrum begins in the medial temporal lobe structure, which can be recognized...
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